Fluid composition Flashcards
Solution
Any homogenous mixture
usually in liquid state
Solvent
A substance whose physical state is preserved when a solution is formed.
OR the substance present in the larger amount ex. water
Solute
A substance whose physical state is changed when a solution is formed. Ex. NaCl
Intracellular vs. extracellular environments
Intracellular- solution inside the cell
Extracellular- solution outside the cell
Breakdown of the total body water
Total body water = 60%
Intracelluar fluid (ICF) = 40%
Extracellular fluid (ECF) = 20%
ECF made up of:
Interstitial fluid (ICF) = 15%
Plasma = 5%
Transcellular fluid = varies (ex. urine in bladder)
Ion distribution in ICF and ECF
ECF: Higher levels of Na and Cl
ICF: higher levels of K
Electroneutrality
Any part of our body should always have an equal number of positive and negative charges. So if a negative charge comes in, a positive charge must go out.
Plasma concentration (solutes)
Plasma = 91% water
Solutes= 9% (2% salt, 7% proteins)
Dissociable vs. non-dissociable solutes
Dissociable- able to be separated which is why they are used in IV fluids Ex. NaCl, KCl, CaCl2, MgCl2, NaHCO3 (sodium bicarbonate)
Non-dissociable- not able to be separated.
Ex. glucose, urea, albumin
Valence charge of ions
Na+, K+, Mg2+, Ca2+, Cl-
Molarity (M)
number of moles of solute in 1L of solution
Molality (m)
Number of moles of solute in 1kg of solvent
Percent weight Volume (%w/v)
Number of grams of solute in 100mL of solution
Osmolarity (Osm)
number of osmoles (osmotically active solute) in 1L solution
Osmolality (Osm/kg)
Number of osmoles (osmotically active solute) in 1kg of solvent