Fluid Comp And Homeostasis Flashcards

1
Q

Name the four body fluid compartments.

A

1) Intracellular fluid (ICF)
2) Extracellular fluid (ECF)
3) Interstitial fluid
4) Plasma

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2
Q

How much of the body’s total body weight is comprised of water?

A

60%

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3
Q

Of the total body water (TBW), what is the ratio of ICF to ECF?

A

2:1

(2/3 TBW ICF)

(1/3 TBW ECF)

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4
Q

Extracellular fluid (ECF) is comprised of _______ and ________.

A

Interstitial fluid.

Plasma.

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5
Q

What % of ECF does interstitial fluid comprise?

A

80%

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6
Q

What % of ECF does plasma comprise?

A

20%

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7
Q

What separates the ICF from the ECF?

A

Cell membrane or plasma membrane.

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8
Q

What is intracellular fluid comprised of? (3 examples)

A

Sodium.

Potassium.

Protein concentrations.

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9
Q

The composition of ECF is similar to _______.

A

Seawater.

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10
Q

What separates interstitial fluid from blood plasma?

A

Capillary wall.

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11
Q

Both plasma and interstitial fluid contain similar molecules/ions (I.e. Na, Ca, K). What is the one component plasma contains that interstitial fluid contains very little of?

A

Plasma proteins.

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12
Q

What are plasma proteins important for?

A

Keeping fluid inside the cardiovascular system.

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13
Q

What is it called when there is too much interstitial fluid?

A

Edema.

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14
Q

Define homeostasis.

A

The relative constancy of the internal environment.

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15
Q

In homeostasis, variables do not stay _______ and constantly ________ around a ________ ________.

A

Constant.

Fluctuates.

Normal range.

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16
Q

Homeostasis is in a state of _______ _______.

A

Dynamic constancy.

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17
Q

At rest, the inside of a cell is what?

A

Slightly negative.

18
Q

When activated, the inside of a cell becomes what?

19
Q

When an activated cell becomes positive, it generates what?

A

An action potential (AP).

20
Q

Activation of a cell is largely dependent upon what?

A

Concentrations of various ions in the interstitial fluid.

21
Q

What does the body do in response to changes in the ECF composition? Why?

A

Initiates reactions.

To correct or minimize changes.

22
Q

Name 4 homeostatic control systems.

A

1) Ions, pH
2) Fluids
3) Blood sugar
4) Body temperature

23
Q

How can you increase body temperature when it drops?

A

1) Need a sensor or sensors
2) Need an integrating center to compare against a set point
3) Need effectors

24
Q

What continuously senses core temperature of body?

A

Thermoreceptors.

25
Where is sensor information sent?
Integrating center.
26
Where is the integrating center located and what does it do?
The hypothalamus and it compares variables to a set point. It then will produce changes in effectors to adjust for deviation from set point.
27
What are some examples of effector response to decreased body temperature?
1) Constriction of blood vessels 2) Curling up via voluntary muscles 3) Shivering (general muscle activity)
28
Define negative feedback and give an example.
Counter action of an effect by its own influence. When body temperature drops, the body will try to warm back up.
29
What is a reflex arc?
A biological control system that directly links a stimulus to its response.
30
List the steps of a homeostatic reflex arc.
1) Stimulus 2) Receptor 3) Afferent pathway 4) Integrating center 5) Efferent pathway 6) Effector 7) Response
31
What is a stimulus?
A detectable change in controlled variable.
32
What is a receptor?
The sensor on which a stimulus acts.
33
Negative feedback typically induces a lag time, therefore a ______ ______ is needed. What does this mechanism do?
Feedforward mechanism. Anticipates changes to minimize fluctuations.
34
Give an example of a feedforward mechanism.
Olfactory cues to turn on digestive system.
35
Define positive feedback and provide an example.
When a stimulus initiates an amplification of its effect by own influence. Hormonal control of uterine contractions during childbirth.
36
What do homeostatic responses rely upon?
Communication between cells to cause a response.
37
Communication between cells happens using different messengers. Name the 4 broad types.
1) Hormones 2) Neurotransmitters 3) Paracrine agents 4) Autocrine agents
38
Define a hormone and it’s location in the body.
A chemical messenger secreted by endocrine cells. Found in bloodstream.
39
Define a neurotransmitter and it’s location in the body.
A chemical messenger released by a neuron. Affects muscles, glands, and nerves. Travels synaptic cleft.
40
Define a paracrine agent.
A chemical messenger released by a cell that acts on nearby cells.
41
Define an autocrine agent.
A chemical messenger released into the interstitial fluid that acts upon the cell that secreted it.
42
What characteristic of chemical messengers determines what we call them?
Where their endpoint location is.