Fluid Balance & Intravenous Therapy Lecture Flashcards
What percent of fluid in the body is water?
Why is fluid in the body important? (3)
What is it affected by?
60% of body fluid is water
1.Transports nutrients & oxygen to cells
2.Removes wastes from cells
3.Regulates body temperature
Affected: Age, Gender, Body Fat
What is the most accurate way to measure fluid status in a pt?
Daily Weights
(Homeostatic Mechanisms)
Hydro-static pressure: 1
Filtration: 2
Diffusion: 3
Osmosis: 4
1.generated by the
cardiovascular system as blood is pumped through the body’s blood vessels
2.occurs when water and solutes are transported across the cell membrane
as a result of this pressure
3.solutes (particles) move from an area of higher concentration to an area of lower concentration
4.fluid moves from areas with more fluid concentration (and fewer solutes) to areas with less fluid concentration (and more solutes)
Normal movement of fluids through the capillary wall into the tissues depends on 2 forces:
- Hydrostatic Pressure:(exerted by pumping of the HEART) :pushing fluid out of capillaries (vessel into tissue) (THINK HEART)
- Oncotic Pressure: the ‘pulling force’ pulling fluids from the surrounding tissue into the capillaries. ( THINK ALBUMIN)
The relationship between Hydrostatic pressure and Oncotic pressure needs to remain?
hydrostatic and oncotic needs to be balanced!!
HOMEOSTATIC MECHANISM
What is third spacing?
a condition where fluid accumulates in a pocket that isn’t serving a purpose (ascites )– fluids in abdominal cavity – peritonitis.
Is edema the same as third spacing?
causes of edema:
Not necessarily
1.Long periods of standing or sitting
2.Venous insufficiency
3.Chronic (long-term) lung diseases (Crackles:base of lung caused by edema)
4.CHF
5.Pregnancy
6.Malnutrition low protein
What is Anasarca?
severe swelling in the entire body… very swollen towards the end of life… due to organ failure
What is the sodium potassium pump?
(Maintain Homeostasis)
Sodium & Potassium use ATP to move in & out of cells in a form of active transport.
Body Fluid is divided into 2 components:
Fluid found inside the cells = intracellular – 2/3 of fluid
Fluid found outside the cells = extracellular – 1/3 of fluid Vascular vein interstitial tissues trans-cellular surrounding.
*To maintain balance or homeostasis fluids inside the cell must be balanced with extracellular fluid. Fluids outside the cell must be balanced with intracellular fluid
Osmolarity & Osmolality:
concentration of solutes in a fluid.
Looking at the osmolality between the intracellular and extracellular fluids:
- extracellular fluids increase by 2-3% osmolality increase is going to increase thirst our solutes in extracellular are higher = makes us want to drink more
- intracellular 10-15% change in blood volume loss
cellular dehydration
Fluid Concentrations and their solutions for fluid replacement:
- Isotonic – remain intravascular – I so perfect – don’t need a change so doesn’t cause any change
Normal Saline (0.9%NaCl)
2.Hypotonic fluids – hippo; fluids moving into cells like a hippo: ½ Normal Saline - Hypertonic – hyper = energy; make cells skinny; fluid escaping from cell
D5 Normal Saline
Maintaining Balance/Fluid Balance: (7)
Kidneys, ADH, Renin-angiotensis-aldosterone system (RAAS), Aldosterone, Atrial Natiuretic peptide, THIRST, Lymphatic system
Kidneys are the King of fluid balance, how ?
Removes excess waste from the body
Sodium & potassium are also either filtered or reabsorbed
How do the kidneys regulate fluid and electrolyte balance?
by adjusting urine volume and the excretion of electrolytes
How does ADH restore blood volume?
Reducing Diuresis
Increasing water retention
Vasoconstriction
What is the medication form of ADH?
Vasopressin (Desmopressin)
Where is ADH stored and produced?
Produced by hypothalamus & stored in pituitary
ADH Vasoconstriction:
shrinks down blood vessels; helps raise blood pressure
If you lose too much fluid, how does this affect you BP?
lost to much fluid : low blood pressure
What activates RAAS?
cascade is initiated by a decrease in renal perfusion or a low sodium – low blood pressure can activate RAAS system or low extracellular fluid.
What does aldosterone do in the body?
helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body.
Too much aldosterone can cause?
high blood pressure and a build-up of fluid in body tissues.
What is the role of atrial natriuretic peptide (ANP)?
main function is to lower blood pressure by vasodilation and to control electrolyte homeostasis.
How does ANP regulate blood pressure?
When blood sodium levels and pressure are increased, ANP is secreted from the heart. It binds to its receptor in the kidney and blood vessels, and promotes salt excretion, lowers blood volume and relaxes the vessel
ANP reduces fluid volume by?
Increasing secretion of Na+ and water
What does a high BNP mean?
BNP levels go up when the heart cannot pump the way it should.
The higher the number, the more likely heart failure is present and the more severe it is.
What is the simplest method of maintaining fluid balance? where is it regulated?
THIRST
(regulated by the hypothalamus)
How is thirst stimulated?
Increase in ECF and drying of mucus membranes