fluid balance Flashcards
how do age gender fat affect fluid balance (amount of body made up of fluid)
inc age-dec boy fluid
men have inc body fluid
overweight people have less fluid % than most people
which parts of the body (tissues have the most water)
o Muscle skin and blood have the highest amount of water
o , body fat=less fluid because fat cells contain little water
what percentage body fluids are intra/extracellular
Intracellular 30 liters
Extracellular 12 liters Interstitial 9 liters Intravascular 3 liters Fluid in body spaces negligible Transcellular spaces
causes of hypervolemia (FVE)
o HF, renal failure, cirrhosis of the liver, consumption of excessive amounts of salt
o Increased ingestion (iatrogenic- d/t incorrect IV)
o Increased retention (cardiac disease)
o Decreased excretion (liver and renal failure)
Causes Increased ingestion iatrogenic Increased retention Cardiac disease Decreased excretion Liver failure Renal failure
s/s hypervolemia FVE
o Clinical manifestations result from the expansion of the ECF and include: generalized edema, distended neck veins, pulmonary edema, dyspnea, cough, SOB, crackles, tachycardia, full bounding pulse, pulse pressure, central venous pressure, increased weight, increased urine output Acute weight gain
ascites CVS symptoms ^BP, ^HR, ^JVP, peripheral edema RS symptoms Pulmonary edema
example of interstitial fluid
Interstitial eg lymph and other fluids that surround the cell
example of transcellular fluid
Transcellular eg CSF, pericardial, synovial, intraocular, pleural
causes of third space fluid shifts
o Third space fluid shifts can occur in pts w severe liver diseases, hypocalcemia, dec iron intake, alcoholism, hypothyroidism, malabsorption, immobility, burns, CA
s/s third spacing
S/S of thrd spacing o Early evi of third space shift is dec in urine output despite adequate intake o Inc HR o Dec BP o Dec central venous pressure o Edema o Inc body weight o Imbalanced I/O
what type of body fluid are elctrolytes meas in
plasma
is an anion or a cation positively charged
what is a example of this that is plentiful
cation
sodium ions
where is sodium most concentrated
in the ECF
major electrolytes in the ICF
potassium
phosphate
what is oncotic pressure
o Oncotic P is the osmotic P exerted by proteins eg albumin
what is the inc in urine output caused by the excretion of substances such as glucose etc called?
o Osmotic diuresis
o Usual daily urine volume in adult is
1-2 litres
how much can an adut sweat in an hour in litres
1 or more
how can water be insensibly lost from a person
perspiration.. Fever and burns inc insensible water loss
o Lungs-approx 300ml of insensible water loss/day
o Gi usually lose 100-200ml daily
what is urine specific gravity
o Urine specific gravity meas kidneys ability to excrete or conserve water (its gravity gets compared to water) it is less specifc than urine osmolality. it can be done using a dipstick. inc glucose or protein in urine can cause a falsely elevated specific gravity
how are dehydration and FVD different
o Dehydration is NOT the same as FVD; dehydration is loss of water with an increase concentration of Na
how are the kidneys involved in fluid regulation
• Kidneys filter 18-L plasma every day and excrete 1-2L fluid
o Role of kidney:
Regulate ECF volume and osmolarity by selective retention and excretion of body fluids
Regulation of usual electrolyte levels in ECF by selective electrolyte retention and excretion
Regulation of pH of the ECF by retention of hydrogen ions
Excretion of metb wastes and toxic substances
how would a heart w dec CO affect water and electrolyte reg
the heart might not circ enough blood to kidneys and not allow for urine formation
how are the lungs involved in fluid balance
• Lungs
o Exhale 300mL of water a day
if hyperpnea (abnormally deep respirations) or continuous coughing then loss will inc
which glands are involved in reg of fluid balance. how?
- Hypothalamus: makes ADH, which is stored in the pituitary gland
- Adrenal Fx: aldosterone secreted by adrenal cortex; sodium (and water) retention, K loss
- Parathyroid: regulate Ca and phosphate and PTH
for interest: what are osmoreceptors
on the surface of hypothalamus. sense changes in sodiu conc. w dehydration they send signal to p. pituitary which rel ADH
creatinine
it the end product of muscle metb.
better inicator of kindy fx than BUN
serum creatinine inc when kidney fx dec
what inc and dec HCT
inc: -dehydration -polycythemia dec: -anemia -overhydration