Fluid Balance Flashcards
2 basic functions of fluid
- Provide transportation of nutrients to cell and waste from cell
- Provides medium for chemical reactions
Composition of water in the body
Adult male 60%
Adult female 50%
Infants (under 2) 60-80%
Elderly (over 45) 45-55%
Why do females have lower body composition of water than males?
females have higher composition of body fat and fat cells contain very little water
Why do the elderly have a lower composition of water?
muscle atrophy
How does the body lose fluid?
kidneys, GI tract, lungs, skin
How much fluid is lost through the kidneys daily?
about 1500 cc daily
How much fluid is lost through the GI tract daily?
150-200 cc daily
8-10 liters is secreted but most is reabsorbed
How much fluid is lost through the lungs daily?
300-400 cc daily
How much fluid is lost through the skin daily?
400-500 cc daily
Sensible & insensible
What is sensible fluid loss through the skin?
sweating
What is insensible fluid loss through the skin?
evaporation
How do we replenish fluids?
liquids & fluids
How much fluid do we need in 24 hours?
30 cc/kg
How is food replenished via food?
Meats, fruits and veggies contain 60-97% water
Oxidation of carbohydrates, fats or proteins via TCA (Krebs) Cycle–10 cc of water for every 100 calories
Where is the majority of water in children?
interstitial space
Do adults of children have a greater metabolic rate?
children
daily fluid needs for children
Premature 50-70 ml/kg Newborn 80-100 ml/kg Newborn-1 year 150 ml/kg 1-2 years 100 ml/kg 2-4 years 90ml/kg 4-10 years 50-70 ml/kg > 10 years 40 ml/kg
Volume of fluid in intracellular fluid compartments
25 liters
Volume of fluid in extracellular fluid compartments
15 liters
3 extracellular fluid compartments
interstitial
intravascular
transcellular
What is interstitial fluid?
fluid surrounding the cell
Volume of interstitial fluid
8 liters
What is intravascular fluid?
fluid within blood vessels
Volume of intravascular fluid
5-6 liters
What is transcellular fluid?
fluid secreted by epithelial cells
examples of transcellular fluid
CSF, pericardial fluid, pleural fluid, synovial fluid, intraocular fluid, digestive secretions
Volume of transcellular fluid
1 liter
first spacing
normal fluid distribution
second spacing
interstitial edema
third spacing
fluid in areas with little or no fluid normally
examples of third spacing
ascites, pleural effusion, pericardial effusion
transport processes that effect movement of water and solutes
diffusion
active transport
flitration
osmosis
examples of solutes that move by facilitated diffusion
insulin
glucose
example of active transport
Na+/K+ pump
what type of transport id dependent on hydrostatic pressure?
filtration
Why are diabetics constantly thirsty and frequently urinate?
glucose has strong osmotic pull
Osmolarity of water
280-294 mOsm/kg
tonicity
ability of particles to affect the movement of water
fluid movement in isotonic solutions
no net movement
fluid movement in hypotonic solutions
fluid moves into cell (cells can burst)
fluid movement in hypertonic solutions
fluid moves out of cell (cells can shrivel)
locations of volume receptors (baroreceptors)
carotid sinuses, aortic arch, cardiac atria & renal vessles
what type of IV fluids can diffuse through the capillary wall
crystalloid solutions
what type of IV fluids cannnot pass through capillary wall
colloid solutions
what are colloid solutions used to treat
severe deficit or shock
what type of IV fluids increase osmotic pressure in vascular space
colloid solutions
what type of IV fluids are plasma or volume expanders
colloid solutions
what compartment(s) expand with hypotonic solutions?
ECF and ICF
what compartment(s) expand with isotonic solutions
ECF only
what tonicity is best for patients with extracellular fluid deficit?
isotonic solutions
how do hypertonic solutions work?
by raising osmolarity of ECF and expanding it; draw water out of cell into ECF
what is the danger of hypertonic solutions?
intravascular fluid volume excess
What is tonicity of D5%W?
isotonic (278)
What is tonicity of D10%W?
hypertonic (556)
What is tonicity of 0.45% saline?
hypotonic (154)
What is tonicity of 0.9% saline (NS)?
isotonic (308)
What is tonicity of 3% NaCl?
hypertonic (1026)
What is tonicity of D5% 0.225% (D5 1/4)?
isotonic (355)
What is tonicity of D5% 0.45% (D5 1/2)?
hypertonic (432)
What is tonicity of D5% 0.9% (D5NS)?
hypertonic (586)
What is tonicity of Ringer’s Solution?
isotonic (309)
What is tonicity of Lactated Ringers?
isotonic (274)
What is Ringer’s Solution?
similar to plasma, excess Cl, no Mg, no HCO3
What is Lactated Ringers?
contains Na K, Cl, Ca, lactate in same proportion as ECF
What type of solution is blood?
colloid
When is whole blood given?
emergency situations
What is PRBC?
red blood cells in 20% plasma
What does giving as a split unit mean?
giving over 8 hours instead of 4 hours
When are platelets given?
thrombocytopenia
What as the opposite effect of warfarin (coumadin)?
fresh frozen plasma
What proportion of fresh frozen plasma is given compared to PRBCs?
1 unit of FFP per 6 units PRBCs
What is fresh frozen plasma?
clotting factors
What is cryoprecipitate?
specialized clotting factors
When volume receptors sense change, what 4 things can change?
cardiac output
vascular resistance
thirst
renal handling of sodium and water
What systems/steroids/hormones regulate fluid?
sympathetic nervous system renin-angiotensin I/II system aldosterone atrial natriuretic factor antidiuretic hormone thirst (osmoreceptors)
What does aldosterone do?
holds onto sodium
What does atrial natriuretic factor (ANF) do?
reduces blood pressure and circulating volume
inhibits secretion and effects of ADH
What do ADH do?
hangs onto water
What is the earliest symptom of a water deficit?
thirst
What patient assessments should be done when looking at fluid volume?
history daily weights (1 kg = 1 L fluid) integument mucous membranes intake and output vital signs cardiovascular system (hemodynamic monitoring) nervous system (mentation) GI system (anorexia, nausea, constipation, diarrhea, thirst) Chemistry (H&H, electrolytes)
What should normal urine output be?
0.5cc/kg/hr
how does water affect body temperature?
water cools body
What is capillary hydrostatic pressure?
pressure exerted by fluid inside capillary outward against capillary membrane
How does capillary hydrostatic pressure work?
filtration
What is capillary hydrostatic pressure on arterial end?
32 mm Hg
What is capillary hydrostatic pressure on venous end?
12 mm Hg
What is Interstitial Fluid Pressure?
pressure exerted by fluid outside capillary against capillary membrane–about 1 mm Hg
What does Interstitial Fluid Pressure do?
maintains integrity of interstitial space
What is plasma colloidal oncotic pressure?
pressure exerted by osmotic pull of proteins inside the blood vessels
What does plasma colloidal oncotic pressure do?
pulls fluid from interstitial space into blood vessel
What is plasma colloidal oncotic pressure on arterial end?
22 mm Hg
What is plasma colloidal oncotic pressure on venous end?
22 mm Hg
What can affect plasma colloidal oncotic pressure?
change in the amount of protein in the plasma
What is tissue colloidal osmotic pressure?
pressure exerted by osmotic pull of proteins in interstitial space–about 1 mm Hg
What can affect tissue colloidal osmotic pressure?
increase in protein in interstitial space
What 2 pressures maintain interstitial space?
tissue colloidal osmotic pressure
interstitial fluid pressure
Where is the excess fluid in vascular hypervolemia?
vascular space
Where is the excess fluid when edema occurs?
interstitial space
Where is the excess fluid in water intoxication?
intracellular space
Where is the excess fluid in third spacing?
transcellular space
How does vascular hypervolemia affect blood pressure?
increases blood pressure
What will the pulse of a patient with vascular hypervolemia?
full and bounding
What are the clinical findings in a patient with vascular hypervolemia?
increase in blood pressure full, bounding pulses distended peripheral veins increased JVD increase in central venous pressure signs and symptoms of pulmonary edema
What interventions should a nurse take with a patient with vascular hypervolemia?
decrease IV to KVO elevate head of bed with legs in dependent position (decreases venous return) decrease anxiety morphine IV (decrease preload and afterload) diuretics via IV or PO oxygen via nasal cannula measure I/O daily weights rotating tourniquets (rare) nitroprusside (dilates blood vessels)
Why does morphine decrease preload and afterload?
It is a vasodilator
What is edema?
fluid in interstitial space
Where will edema first appear?
tissues poorly protected against hydrostatic pressure (ankles, sacrum if bedridden)
What causes edema?
immobility
injury
obstruction in lymphatic drainage
hypoproteinemia (low protein in blood)
What are clinical findings of a patient with edema?
puffy eyelids, bags under eyes pale, tight, shiny skin swollen ankles enlarged abdomen (liver issues) shoes, rings and belt tight shortness of breath, dyspnea, moist rales, hoarseness (if lungs are affected)
What are nursing interventions for edema?
elevate effected body part
promote activity when possible
diuretics (IV or PO)
Fluid restrictions (may have sodium restrictions too)
avoid constrictive clothing
avoid crossing legs or sitting in ways that restrict circulation
What cause water intoxication?
excess IVs (especially hypotonic solutions)
sterile water for irrigation post-TURP
tap water enema
psychogenic polydipsia (extremely thirsty)
What are the clinical findings in a patient with water intoxication?
disturbed thought and behavior (apprehension, irritability, restlessness, confusion, lethargy, coma)
decrease in serum electrolytes (hyponatremia)
pulmonary edema
will not usually see visible edema
What are nursing interventions for water intoxication?
monitor IVs to prevent too much fluid intake
monitor urinary output
assess serum Na+
administer plasma expanders (albumin, mannitol, dextran)
diuretics (increase flow through kidneys)
What is third spacing?
fluids move into inaccessible spaces and are retained there
If there is a drop in blood pressure & increase in pulse without increase in urine output or decrease in body weight, what should you suspect?
third spacing
What type of fluid excess is know as relative dehydration?
third spacing
What are some cause of third spacing?
intestinal obstruction
cellulitis
crushing injury
vascular occlusions
Where are some places third spacing can occur?
pleural space pericardial space eye synovial space CNS
What are treatments for third spacing?
IV plasma expanders
crystalloids to support vascular space
mechanical removal of fluid (thoracentesis, paracentesis)
What is one reason you should be cautious with third spacing?
fluid can move back into intravascular space at any time
What are the 3 stages of fluid deficit?
simple dehydration
advanced fluid loss
hypovolemic shock
What are the signs of simple dehydration?
dry skin
loss of skin turgor
weight loss
What are the signs of advanced fluid loss?
falling blood pressure
weak, thready, rapid pulse
What are the signs of hypovolemic shock?
signs and symptoms of renal failure
What are the clinical findings of fluid deficit?
thirst
dry skin and mucous membranes (be concerned if armpits are dry)
hollow, sunken eyes (especially in children)
shrunken wrinkled furrowed tongue (scrotal tongue)
mild temperature elevation
weight loss
orthostatic hypotension with decreased blood pressure and tachycardia
pale, cold extremities (due to peripheral vasoconstriction)
oliguria that progresses to anuria (low urine to no urine)
dark, concentrated urine with high specific gravity
increase in H & H (hemoglobin & hematocrit), Na+, serum osmolarity
apathy, fatigue, stupor, delirium (due to hyperosmolar state affecting CNS)
What are nursing interventions for fluid deficit?
Give fluids (PO or IV depending on stage)
Monitor IV fluids carefully (do not want to over hydrate)–reverse hypernatremia slowly
I/O
Daily Weight
Scrupulous oral care
adequate nutrition
What is an isotonic imbalance?
sodium and water increase or decrease together
watch for symptoms of hypovolemia and hypervolemia
What is hypotonic imbalance?
Too much water or not enough sodium
What is hypertonic imbalance
Too much sodium or not enough water