First Year Flashcards
CAP
CURB-65 score of 0-2
Amoxicillin 1g TDS IV/PO - 5 days
CAP
CURB-65 of 0-2
Penicillin allergic
Doxycycline PO 200 mg OD (or IV Clarithromcyin if NBM)
CAP
CUBR-65 of 3-5
Co-amoxiclavIV 1.2 g TDS + Doxycycline PO 100 mg BD
CAP
CUBR-65 of 3-5
Penicillin allergic
IV Levofloxacin 500 mg
CAP
ICU/HDU or NBM
Co-amoxiclav IV 1.2g TDS + Clarithromycin IV 500 mg BD
CAP
ICU/HDU or NBM
Penicllin allergic
IV Levofloxacin 500 mg
How long should IV/PO antibiotics be given for CAP?
Total = 7 days
For al patients with severe CAP you should step down to?
Doxycycline 100 mg BD
HAP
Severe
IV Amoxicillin + Metronidazole + Gentamicin
HAP
Severe
Penicillin allergic
How many days in total?
IV Co-trimoxazole + Metronidazole +/- Gentamicin
Step down to PO Co-trimoxazole + Metronidazole
Total IV/PO = 7 days
HAP
Non-Severe
PO Amoxicillin + Metronidazole for 5 days
HAP
Non-severe
Penicillin allergic
PO Co-trimoxazole + Metronidazole
When should you seek advice about abx for HAP?
Previous ICU admission or history of MRSA
When do you give antibiotics for an acute exacerbation of COPD?
If increased sputum purulence. If not - then no antibiotics unless consolidation on CXR or signs of pneumonia
1st line
COPD exacerbation
Amoxicillin 500 mg TDS
2nd line
COPD exacerbation
Doxycycline 200 mg on day 1 then 100 mg daily
5 days
When are abx considered in acute cough/bronchitis?
Frail elderly
1st line
Acute cough/bronchitis?
Amoxicillin 500 mg TDS
2nd line
Acute cough/bronchitis
Doxycycline 200 mg on day 1 then 100 mg daily
5 days
Native valve infective endocarditis
IV Amoxicillin + IV Gentamicin
Acute severe sepsis
Native valve
Infective endocarditis
IV Flucloxacillin
Prosthetic valve or suspected MRSA
Infective endocardiits
Vancomycin IV + Gentamicin IV
Add in Rifampicin PO 3-5 days later
PWID
Infective endocarditis
Flucloxacilin IV
Then as guided by culture
Staph aureus (non-MRSA) Infective endocarditis
Flucloxacillin IV
MRSA
Infective endocarditis
Vancomycin IV + Gentamicin IV + add Rifampicin PO 3-5 days later
Strep viridans
Infective endocarditis
Benzylpenicillin IV + Gentamicin IV
Staph Epidermidis
Infective endocarditis
Vancomycin IV + Gentamicin IV + Rifampicin PO 3-5 days later
Enterococcus sp
Infective endocarditis
Amoxicillin or Vancomycin IV + Gentamicin IV
How long are antibiotics given in infective antibiotics?
Typically 4-6 weeks
What do you monitor during Infective endocarditis treatment?
Cardiac function
Temperature
CRp
How do you treat non-severe C. diff infection?
Metronidazole PO - 10 days
How do you treat severe C. diff?
Vancomycin PO/NG - 10 days
+/- Metronidazole
How do you treat peritonitis/biliary tract/intra-abominal sepsis?
IV Amoxicillin + Gentamicin + Metronidazole
Then step down to CO-trimoxazole + Metronidazole
How do you treat peritonitis/biliary tract/intra-abominal sepsis if penicillin allergic?
IV Vancomycin + Metronidazole + Gentamicin
Step down to PO Co-trimoxazole + Metronidazole
How do you treat severe proven spontaneous bacterial peritonitis?
Piperacillin/Tazobactam then step down to Co-trimoxazole PO (5-7 days)
How do you treat mild proven spontaneous bacterial peritonitis`
Co-trimoxazole PO (5-7 days)
