first line of defense (innate immunity) Flashcards

1
Q

what are the physical and mechanical barriers of innate immunity that are the 1st line defense

A

skin
hair
mucous membrane
coughing/sneezing/vomiting

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2
Q

what do the biochemical barriers that are apart of the first line of defense do

A

synthesize & secrete substances to trap or
destroy microorganisms via antibacterial peptides

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3
Q

where do the biochemical barriers of the first line of defense trap, destroy microorganisms via antibacterial peptides

A

Mucous secretions
 Perspiration
 Saliva
 Tears
 Earwax

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4
Q

what are the 2 classes of antimicrobial peptides produced by epithelial cells

A

Cathelicidins & defensins

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5
Q

what does the normal microbiome do

A

provides protection by inhibiting colonization and
multiplication of pathogens and by releasing chemicals that prevent
infection

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