first line of defense (innate immunity) Flashcards
what are the physical and mechanical barriers of innate immunity that are the 1st line defense
skin
hair
mucous membrane
coughing/sneezing/vomiting
what do the biochemical barriers that are apart of the first line of defense do
synthesize & secrete substances to trap or
destroy microorganisms via antibacterial peptides
where do the biochemical barriers of the first line of defense trap, destroy microorganisms via antibacterial peptides
Mucous secretions
Perspiration
Saliva
Tears
Earwax
what are the 2 classes of antimicrobial peptides produced by epithelial cells
Cathelicidins & defensins
what does the normal microbiome do
provides protection by inhibiting colonization and
multiplication of pathogens and by releasing chemicals that prevent
infection