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P&T ID > First Generation Cephalosporins > Flashcards

First Generation Cephalosporins Flashcards

1
Q

List of 1st Generation Cephalosporins

A

Cefazolin

Cephalexin

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2
Q

Whats Mechanism of Action 1st Generation Cephalosporins?

A

Bata-lactam inhibits cross-linking of peptidoglycan in the cell wall, leading to autolysis and cell death.

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3
Q

Spectrum of 1st Generation Cephalosporins?

A

MSSA, Streptococci

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4
Q

can 1st Generation Cephalosporins be used for CNS infections?

A

No. they do not cross the blood brain barrier

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5
Q

Whats the most important indication for 1st Generation Cephalosporins?

A

Surgical prophylaxis

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P&T ID (9 decks)

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