Finals Drug List Flashcards
cetirizine
allergy (H1 antagonist)
fingolimod
multiple sclerosis (S1P agonist)
formorterol
asthma (b2 agonist)
montelukast
asthma (LTD4 antagonist)
phenylephrine
nasal decongestant (a1 agonist)
penicillin
antibiotic (ADR: anaphylaxis)
NSAIDs
ibuprofen (ADR: nephrotoxicity)
corticosteroids
ADR: hypothalamus-pituitary-adrenal (HPA) axis insufficiency crisis
antihistamines
ADR: drowsiness, impaired coordination and alertness
codeine
opiates (ADR: flushing, urticaria, red man syndrome)
cetirizine
2nd gen antihistamine
loratadine
2nd gen antihistamine
fexofenadine
2nd gen antihistamine
diphenhydramine
1st gen antihistamine
promethazine
1st gen antihistamine
chlorpheniramine
1st gen antihistamine
aspirin
COX-1 selective inhibitor (ADR: bleeding, asthma, reye’s syndrome)
ibuprofen
COX-1 selective inhibitor
naproxen
COX-1 selective inhibitor
celecoxib
COX-2 selective inhibitor
paracetamol
COX-3 selective inhibitor (CNS)
prednisone
cortisone + 1,2 db (high DOA, low water retention)
prednisolone
hydrocortisone (cortisol) + 1,2 db (high DOA, low water retention)
methylprednisolone
prednisolone + 6-methyl (high DOA, no water retention)
dexamethasone
triamcinolone (methylprednisolone + 9-F) + 16-methyl
(highest DOA, very potent, no water retention)
ciclosporin
calcineurin inhibitor
sirolimus
mTOR inhibitor
azathioprine
cytotoxic agent
mycophenolate mofetil (MMF)
cytotoxic agent
fingolimod
S1P receptor agonist (multiple sclerosis)
formorterol
LABA (bronchodilator)
salbutamol
SABA (bronchodilator)
ipratropium bromide
SAMA (bronchodilator) muscarinic antagonist
tiotropium bromide
LAMA (bronchodilator)
theophylline
Oral-SR (inhibit PDE + block Adenosine receptor)
fluticasone
ICS (anti-inflammatory)
montelukast
LTRA (anti-inflammatory)
sildenafil citrate
PDE 5 inhibitor
tadalafil
PDE 5 inhibitor
roflumilast
PDE 4 inhibitor (COPD)
nitroglycerine
PDE 5 inhibitor (angina)
nitroprusside
PDE 5 inhibitor (anti-hypertensive)
hemicholinium
inhibit choline uptake, reduce ACh synthesis
vesamicol
VAChT inhibitor (block transport of ACh into vesicles)
botulinum toxin (botox)
prevent ACh release (dystonia, cosmetics)
pralidoxime
cholinesterase (AChE) reactivators (reduce ACh)
atropine
non-selective muscarinic antagonist (blocks all muscarinic receptors)
bethanecol
urinary retention, GI hypotonia
pilocarpine
glaucoma
succinylcholine
muscle relaxant (rapid endotracheal intubation, depolarizing blocker)
pancuronium
muscle relaxant, paralysis (non-depolarizing competitive blockers)
anticholinerases
AChE inhibitors, increase ACh
Erdophonium (SA), Neostigmine (IA), Pyridostigmine (IA), Parathion (LA)
norepineprhine/epinephrine
a/b agonist (anaphylactic shock, cardiac arrest)
salbutamol
b2 agonist (bronchodilator, asthma, premature labour)
phenylephrine
a1 agonist (vasoconstriction, nasal decongestant)
clonidine
a2 partial agonist (hypertension, migraine)
propanolol
non-selective b antagonist (angina, hypertension, cardiac dysrythmia)
a-methyl-p-tyrosine
tyrosine hydroxylase inhibitor (phaechromocytoma)
reserpine
VMAT inhibitor,reduce NA - block vesicular uptake of NA, remain in cytoplasm>degraded (hypertension, schizophrenia)
amphetamine/ephedrine/tyramine
increase NA release without depolarizing membrane
cocaine
reduce reuptake of NA into cytoplasm
moclobemide
MAO inhibitor- reduce NA breakdown (antidepressant)