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LSM3211 drug list > Finals Drug List > Flashcards

Finals Drug List Flashcards

1
Q

cetirizine

A

allergy (H1 antagonist)

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2
Q

fingolimod

A

multiple sclerosis (S1P agonist)

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3
Q

formorterol

A

asthma (b2 agonist)

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4
Q

montelukast

A

asthma (LTD4 antagonist)

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5
Q

phenylephrine

A

nasal decongestant (a1 agonist)

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6
Q

penicillin

A

antibiotic (ADR: anaphylaxis)

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7
Q

NSAIDs

A

ibuprofen (ADR: nephrotoxicity)

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8
Q

corticosteroids

A

ADR: hypothalamus-pituitary-adrenal (HPA) axis insufficiency crisis

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9
Q

antihistamines

A

ADR: drowsiness, impaired coordination and alertness

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10
Q

codeine

A

opiates (ADR: flushing, urticaria, red man syndrome)

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11
Q

cetirizine

A

2nd gen antihistamine

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12
Q

loratadine

A

2nd gen antihistamine

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13
Q

fexofenadine

A

2nd gen antihistamine

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14
Q

diphenhydramine

A

1st gen antihistamine

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15
Q

promethazine

A

1st gen antihistamine

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16
Q

chlorpheniramine

A

1st gen antihistamine

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17
Q

aspirin

A

COX-1 selective inhibitor (ADR: bleeding, asthma, reye’s syndrome)

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18
Q

ibuprofen

A

COX-1 selective inhibitor

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19
Q

naproxen

A

COX-1 selective inhibitor

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20
Q

celecoxib

A

COX-2 selective inhibitor

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21
Q

paracetamol

A

COX-3 selective inhibitor (CNS)

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22
Q

prednisone

A

cortisone + 1,2 db (high DOA, low water retention)

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23
Q

prednisolone

A

hydrocortisone (cortisol) + 1,2 db (high DOA, low water retention)

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24
Q

methylprednisolone

A

prednisolone + 6-methyl (high DOA, no water retention)

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25
Q

dexamethasone

A

triamcinolone (methylprednisolone + 9-F) + 16-methyl
(highest DOA, very potent, no water retention)

26
Q

ciclosporin

A

calcineurin inhibitor

27
Q

sirolimus

A

mTOR inhibitor

28
Q

azathioprine

A

cytotoxic agent

29
Q

mycophenolate mofetil (MMF)

A

cytotoxic agent

30
Q

fingolimod

A

S1P receptor agonist (multiple sclerosis)

31
Q

formorterol

A

LABA (bronchodilator)

32
Q

salbutamol

A

SABA (bronchodilator)

33
Q

ipratropium bromide

A

SAMA (bronchodilator) muscarinic antagonist

34
Q

tiotropium bromide

A

LAMA (bronchodilator)

35
Q

theophylline

A

Oral-SR (inhibit PDE + block Adenosine receptor)

36
Q

fluticasone

A

ICS (anti-inflammatory)

37
Q

montelukast

A

LTRA (anti-inflammatory)

38
Q

sildenafil citrate

A

PDE 5 inhibitor

39
Q

tadalafil

A

PDE 5 inhibitor

40
Q

roflumilast

A

PDE 4 inhibitor (COPD)

41
Q

nitroglycerine

A

PDE 5 inhibitor (angina)

42
Q

nitroprusside

A

PDE 5 inhibitor (anti-hypertensive)

43
Q

hemicholinium

A

inhibit choline uptake, reduce ACh synthesis

44
Q

vesamicol

A

VAChT inhibitor (block transport of ACh into vesicles)

45
Q

botulinum toxin (botox)

A

prevent ACh release (dystonia, cosmetics)

46
Q

pralidoxime

A

cholinesterase (AChE) reactivators (reduce ACh)

47
Q

atropine

A

non-selective muscarinic antagonist (blocks all muscarinic receptors)

48
Q

bethanecol

A

urinary retention, GI hypotonia

49
Q

pilocarpine

50
Q

succinylcholine

A

muscle relaxant (rapid endotracheal intubation, depolarizing blocker)

51
Q

pancuronium

A

muscle relaxant, paralysis (non-depolarizing competitive blockers)

52
Q

anticholinerases

A

AChE inhibitors, increase ACh
Erdophonium (SA), Neostigmine (IA), Pyridostigmine (IA), Parathion (LA)

53
Q

norepineprhine/epinephrine

A

a/b agonist (anaphylactic shock, cardiac arrest)

54
Q

salbutamol

A

b2 agonist (bronchodilator, asthma, premature labour)

55
Q

phenylephrine

A

a1 agonist (vasoconstriction, nasal decongestant)

56
Q

clonidine

A

a2 partial agonist (hypertension, migraine)

57
Q

propanolol

A

non-selective b antagonist (angina, hypertension, cardiac dysrythmia)

58
Q

a-methyl-p-tyrosine

A

tyrosine hydroxylase inhibitor (phaechromocytoma)

59
Q

reserpine

A

VMAT inhibitor,reduce NA - block vesicular uptake of NA, remain in cytoplasm>degraded (hypertension, schizophrenia)

60
Q

amphetamine/ephedrine/tyramine

A

increase NA release without depolarizing membrane

61
Q

cocaine

A

reduce reuptake of NA into cytoplasm

62
Q

moclobemide

A

MAO inhibitor- reduce NA breakdown (antidepressant)

LSM3211 drug list (1 decks)

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