finals Flashcards
Multinucleated
Originated from myoblast precursor cells
Has 3 connective tissue layers
Skeletal muscle
3 connective tissue layers in the skeletal muscle
Epymisium
Perymisium
Endomysium
outermost layer, encircle thr entire muscle
Epymisium
Surrounded by 10-100 or more fibers and separates muscles into bundles called Fascicles
Perymisium
Loacated inside the Fascicles, separating individual muscle fiber from one another
Endomysium
Bundles located in the Perymisium
Fascicles
fluid filled system of the mebranous sacs thar encircles each myofibril
Srcoplasmic Reticulum
Dilated end sacs of SR
Terminal Cisterns
Muscle fibers are relaxed:
SR stores Ca2+
Occur due to releasing Ca2+ from Terminal cisterns
Muscle contraction
2 substantial substances in the Sarcoplasm
Glycogen and Myoglobin
Also called Contractile organelles of the skeletal muscles
Myofibrils
Mainly composed of myosin
Thick filaments
Composed of mainly actin
Thin filament
True or False: both thick and think filaments are involve in contractile process
TRUE
compartment where the 2 filaments are arranged
Sarcomere
Narrow plated shaped region, Anchors the actin rich thin filaments and maintains the mechanical stability of cardiac muscles
Z disc
Dark middle part of the sarcomere, extends the entire length of the thick filament and overlaps areas between thick and thin
A band
lighter zone, contains the rest of the thin filament
I band
Narroe regiom at the Center of each A band that only contains Thick filament
H zone
Region center of the H zone, holds together the thick filament together at the center of the sarcomere
M line
Proteins in the Myofibril: Generates force during contraction
Contractile protein
Protein that helps switch the contraction process On and off
Regulatory
protein
keeps the filament in proper alignment and gives elasticitu and extendability
Structural protein
T or F: the actin and myosin and bands and Z disc in the cardiac muscles are same im the skeletal muscles
True
Unique characteristic of CM
It has intercalated disc
T or F: Cardiac muscles contain both desmosomes and gap junctions
True
True or False: Cardiac muscles does not Lack Epymisium
False, It has endomysium and perymisium but it LACKS Epymisium
Why does the comtraction rate in CM is 10-15x longer than skeletal muscles
Cuz Ca2+ enters the sarcoplasm from SR and instertitial fluids
T or F: CM contraction has its own autorythmic muscle fibers
T
T or F Mitochondria in CM are small and few
F: they are large and numerous
Walls of the small arteries and veins, uterus, urinary bladder and intestines
Visceral
Walls of larger arteries, airways and arrector pili muscles
Multi unit
T/F SM does not have 2 types
F: Visceral and multi unit
Why smooth muscles, smooth?
Its spindle shaped and Non striated
T/F SM contains a single oval and centrally located nucleus.
It contains both filaments
T
WHY SM has a small amount of SR that contains CA2+
cuz it lacks Transverse tubules
Where does the Ca2+ source in SM located
Caveolae, small pouch like invagination in the plasma membrane
Charge different across the plasma mebrane of an unstimulated cell
Resting Potential
T/ F K+ inside is lower than in the outside
F, Higher
T/F Na+ are Higher inside than outside
F, Higher outside
Which is more permeable in the PM K+ or Na+
K+
Reverse of Resting Potential, INSIDE of the PM becomes more positive
Action potential
Value where depolarizatiom changes the membrane potential
THRESHOLD
Synapse between motor neuron and SK muscles
Neuromuscular Junction
what nerves supplies the SK muscles
SOMATIC NERVES/MOTOR NEURON
T/F each Motor neurons DOES NOT branched out in the msucles fibers
Fibers called?
F, it does branch out
Terminal buttons
Organic compound that is found in the body and brain as neurotransmitter
Acetylcholine