Finals Flashcards
Acute pancreatitis Investigations
USS abdo for cause
then CT Abdo with contrast
Which nerves are affected by vestibular schwannoma
CN V VII VIII
Vomiting ABG
High Cl, Low K, Metabolic alkalosis, raised anion gap
Difference between Fe def anaemia and chronic disease anaemia
TIBC high in Fe def, TIBC low in chronic disease
CNIII Palsy
Surgical mx if pupil unreactive –> CT head
Medical if reactive pupil
When is a GLP-1 mimetic used
T2DM when pt is obese and on dual/triple therapy
Pre-diabetic and obese
eGFR that Metformin is CI
<30, use sulfonylurea instead
Mx of inguinal hernia in infant
Surgery ASAP
Crohn’s Mx
Acute - Pred, Biologics 2nd
Maintenance - Azathioprine or Mercaptopurine
Anorexia Changes
Everything low except G and C
High GH, Glucose, Saliva Glands
High Cortisol, CHolesterol, Carotinaemia
CKD Dx
Urinary ACR –> need early morning sample
Elevating the testis - Torsion vs Epidimitis
Torsion - pain NOT relieved
Epididimitis - pain RELIEVED
Most common cause of Viral Encephalitis
HSV
Htn + ACR > 30
Ramipril / ACEi
Cirpofloxacin s/e
Lowers seizure threshold
AAA presentation
Abdo pain, ? mimic renal colic
Hypotension and shocked, + abdo guarding
Pericarditis 1st line Mx
Ibuprofen + colchicene
OGT in pregnancy
24 - 28 wks
Mesenteric Adenitis
Inflamed lymph nodes in mesentery. Similar sx to appendicitis but follows viral infection. ?enlarged lymph nodes
Neuroleptic Malignant Syndrome
Sx - Pyrexia, muscle rigidity, autonomic lability (htn, tachy HR and RR)
Raised CK
Mx: sop antipsychotic, give IV fluid and dantrolene
Trastuzumab use
HER2 positive
Monoclonal Ab targets HER2 receptors
Tamoxifen
ER/PR positive disease
SERM - 1st line in men or pre-menopausal women
Risk: clot, endometrial Ca, osteoporosis
Anastrozole / Letrozole
ER/PR positive
Aromatase Inhibitor - used 1st line in post-menopausal women
S/E - menopausal sx, osteoporosis, MSK pain
AML
Dx >75yr
Film - Auer rods, myeloid blast cells
ALL
Dx - 2-5yr
Film - Blast cells
Philadelphia chromosome
CML
Dx >65 yr
Philadelphia Chromosome
Splenomegaly
3 phases -
Chronic (last 5yrs, asymptomatic),
Accelerated (abnormal blast cells take up high proportion of blood = anaemia + thrombocytopenia),
Blast = V high proportion of blast cells = severe pancytopenia
CLL
Dx >55yr
Film - smear or smudge cells
Richter’s transformation - CLL progresses to high-grade lymphoma
Temporal lobe focal seizure
Aura, racing feeling in stomach, writhing movements