Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Final Year - Rheum > final tutorial > Flashcards

final tutorial Flashcards

1
Q

Septic

A

septic arthritis - one joint
gout -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Management of acute gout

A

NSAID - naproxen
Hx of alcohol disease, CVD, renal failure, peptic ulcer disease or if 65

If no NSAID possible
Colcichine - SE = diarrhoea, so don’t give elderly patient,
Steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What do you give for prevention of gout?

A

Allopurinol - xanthine oxidase inhibitor - give lifelong, but can trigger an attack of gout so give 3 months of colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

RA management - name four drugs. When would you use biologics>

A

Methotrexate - use double contraception
Sulfasalazine - reduces sperm count
Leflunamide
Hydroxychloroquine

If 2 of these don’t work over 6 months, consider a biologic add on and then reduce

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is azathioprine? What is it used for?

A

Azathioprine - steroid sparing agent - lupus and connective tissue diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Management of osteoporosis, side effects and how to use

A

Alendronic acid - SE - oesphageal/GI ulcers or GORD
Or give zolendronate infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Granulomatosis polyangiitis

A

Wegener’s
Middle aged/elederly men

Upper respitatory tract
Sinusitis
Saddle shaped nose
Lower respitaroty tract
CXR - pulmonary nodules

pulmonary haemorrahge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Granulomatosis polyangitis antibody

A

c-ANCA, proteinase 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
A

Churgs strause - MYPO - myeloperoxindase - p ANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HLA B27 features

A

Crohns, IBD, enthesitis, uveitis, dactylitis, psoriasis,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most common organism for reactive arthritis

A

Chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When you would suspect gonorrhoea

A

Rash on hands and feet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Investigation work up for reactive arthritis picture

A

ESR/CRP
Serology RF, CCP, ANA
Urate level to exlude gout
Refer to GUM
Aspirate joint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Management of reactive arthritis

A

NSAIDs, rest, splinting
Steroid injection
DMARDs if more than 3 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When does ESR go up?

A

ESR - infection, inflammation, malignancy, anaemia, renal failure, pregnancy

Ca - 2.84

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

High calcium, high ESR up, what might you see on x ray of spine

A

Vertebral compression fracture

17
Q

Differentials for vertebral fracture

A

Multiple myeloma - send of bloods for electrophoresis, urine for

18
Q

when do you give hydroxychloroquine

A

hydroxylchol - for connectiv tissue disaees

19
Q

what do you give to treat ankylospondylitis

A

NSAIDs, if they don’t work, give biologics - anti-TNF, or anti-IL17 - secucinumab

20
Q

give an example of anti-TNF

A

infliximab = anti-TNF

21
Q

What is arthralgia

A

Pain and stiffness without swelling

22
Q

First line drug for SLE

A

Hydroxychloroquine

23
Q

Three key tests for SLE

A

dsDNA
ESR
c3/c4

24
Q

What are the symptoms of SLE in mild, moderate and severe disease?

A

mild - rash, arthritis, lymphadenopathy
moderate - pleurisy, pericarditis, cytopenias
severe - CNS lupus, glomerulonephritis

25
Q

SLE antibodies

A

Always ANA positive

Anti-SM specific for SLE

26
Q

Ro antibody - pregnancy consequence

A

2 percent risk of neonatal heart block

27
Q

Tx of SLE

A

Hydroxychloroquine for skin/joints
Prednisolone - for flares
Azathioprine - for long term
Mycophenolate
Rituximabl/cyclphosphamide for worse diseaes

28
Q

how do you diagnose psoriatic arthritis

A

Psoriasis - not symmetrical
Dactylitis
Nail oncholysis

29
Q

How much prednisolone do you give for steroids?

A

visual disturbance - give 60mg
no visual disturbance - give 40mg

GCA - large vessel vasculitis, systemic unwellness, fever, malaise, fatigue, myalgias etc

30
Q
A

Over 50s,
Rare in asians, more in caucasians
associated PMR
Temporal artery biopsy
US temporal
CT PET scan to screen for other parts of the body

always do dexa scan and bisphonate alongside steroids

weight gain
cetnarl obesity
htn
diabetes
cataracts
poor wound healing
bruising
thin skin

31
Q
A

weight gain
cetnarl obesity
htn
diabetes
cataracts
poor wound healing
bruising
thin skin

32
Q

Which antibody should you never give with methotrexate and why?

A

Trimethorprim - never give with methotrexate as it depletes folate levels and causes a pancytopenia

33
Q
A

Chest xray - to exlude pulmonary fibrosis, interstitutional pneumonitis

34
Q

What symptoms does sacroiliitis cause

A

sacral
pain and stiffness
no numbness in leg, impingement etc

35
Q
A
36
Q
A

Final Year - Rheum (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions