Final Test Flashcards

1
Q

Cancer

A

Diseases in which certain cells undergo uncontrolled growth.

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2
Q

Metastasis

A

Cancer cells leaving their place of origin, acquire the ability to get into blood vessels/pass through lymphatic wall and then find a comfortable home to establish a new cancer colony.

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3
Q

What process helps us determine whether cancer is malignant or benign?

A

Metastasis. Benign cancer will not metastasize.

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4
Q

Stage 0 cancer

A

Early form of cancer characterized by the cells being present only in the location where they had initially formed.

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5
Q

Stage 1 cancer

A

Localized to a single part of the body and have not grown into nearby tissues.

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6
Q

Stage 2 cancer

A

Still local, but more advanced

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7
Q

Stage 3 cancer

A

Locally advanced but involved lymph nodes being affected

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8
Q

Stage 4 cancer

A

Cancer that has metastasized

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9
Q

Treatments against cancer

A
  • Surgery to remove cancerous mass
  • Chemotherapy and radiation (causes damage to cancer cell DNA and inhibit enzymes needed for their growth)
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10
Q

Immune surveillance hypothesis

A

Immune system is on the alert for pathogens, when it finds something bad it goes into action

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11
Q

Sinoatrial node

A

Natural heart pacemaker - sets rate and timing for cardiac muscle cells to contract

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12
Q

Right atrium

A

Collection of de-oxygenated blood pumped from periphery (via the superior and inferior vena cavae) into right ventricle then to the lungs where CO2 is removed and O2 is added.

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13
Q

Left atrium

A

Receives oxygenated blood from lungs, pumps into left ventricle which then drives it to the body via the aorta.

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14
Q

Blood pressure

A

systolic bp/diastolic bp (typically 120/80)

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15
Q

Systolic bp

A

peak pressure in arteries when ventricles are contracting, pushing blood to the rest of body

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16
Q

Diastolic bp

A

Minimum pressure present when ventricles are filled with blood, before pressure of the heart is applied

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17
Q

Arteries

A

carries o2 blood to organs

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18
Q

veins

A

carries co2 blood to heart

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19
Q

stage 1 hypertension

A

bp = 140-159 over 90-99

20
Q

stage 2 hypertension

A

bp = 160/100

21
Q

secondary hypertension

A

hypertension caused by medical condition

22
Q

essential hypertension

A

hypertension caused by unknown condition

23
Q

hypertension

A

increased bp because of artery size constriction

24
Q

Coronary artery disease

A

buildup of plaque in coronary arteries.
- plaque made up of fat, cholesterol, calcium, waste products and fibrin (clotting factor)

25
Q

artherosclerosis

A

thickening/hardening of the arteries

26
Q

stable angina

A

myocardial ischemia is transient and resolves upon discontinuation of behaviour that places load on the heart (exercise)

27
Q

unstable angina

A

angina present with minimum energy output/at rest

28
Q

True or false: depression is highly predictive of CAD

A

True

29
Q

Why is depression and CAD comorbid?

A

–> Could be a combo of chronic stress or internalized coping strats that instigate changes in physiological processes that promote heart disease.
–> cardiovascular reactivity view: vascular alterations arise in depressed individuals because they are highly reactive to stressful stimuli.
–> ** stressful experiences that accompany/lead to depression give rise to circulating inflammatory factors taht increase vulnerability to heart disease

30
Q

Heart rate variability (HRV)

A

variation in the time between heart beats controlled by sympathetic and parasympathetic NS functioning

31
Q

In response to stressors, HRV is ________

A

decreased

32
Q

In response to diminished stress, HRV is _________

A

increased/normal

33
Q

Treatments for hypertension

A

–> calcium channel blockers: dilate coronary artery to increase blood flow
–> angiotensin converting enzyme inhbitors/angiotesin2 receptor blockers: block angiotensin from being produced/binding to receptor which limits blood vessel constriction to improve blood flow.

34
Q

Common elements of depression

A
  • presence of poor mood or anhedonia
  • need to show 3-4 additional symptoms on top of poor mood and anhedonia to be diagnosed
35
Q

major depression with typical features

A
  • eat less, sleep less, lots of rumination
36
Q

major depression with atypical features

A
  • reversed symptoms of typical: eat more, sleep more, reactive to environmental cues
37
Q

melancholy depression

A

extreme version of typical depression (typical only)

38
Q

Dysthymia

A

-chronic low grade depression which is neither severe nor intense.
- disrupts social functioning
- often goes with personality disorders

39
Q

double depression

A

-depression occurs but then an event happens that makes their depression worse which makes depression hard to modify/treat.

40
Q

3 classes of personality disorders associated with dysthymia

A

avoidant type, narcissistic type, and type in between

41
Q

seasonal affective disorder

A

typical or atypical depression tied to circadian rhythms

42
Q

Recurrent brief depression

A

intense depression that lasts a couple of days, occurs on average even 30-40 days but is not tied to any kind of cycle (menstrual for ex).
- associated with high impulsivity

43
Q

Beck theoretical approach to depression

A
  • challenged the idea that depression is learned, but rather people have different views of the worlds - some being very negative which causes hopelessness. they have a screwed up cognitive function and to fix their depression they need to fix their outlook on life (CBT therapy)
44
Q

Hopelessness

A

believing that no one can change your scenario/make it better

45
Q

Helplessness

A

believing that you cannot control your own situation

46
Q
A