Final Review Flashcards
What is the status of the
Nucleic Acid
Polymerase
and reason why in
picornavirus, norwalk, corona, togavirus, flavivirus
plus-stranded RNA
no pol
virion RNA serves as mRNA to make the polymerase in infected cells
Note: pico (non-enveloped) Norwalk (non-enveloped) Corona (enveloped) Flavi and Toga (enveloped)
What is the status of the
Nucleic Acid
Polymerase
and reason why in
orthomyxovirus
segmented minus-stranded RNA
RNA-dependent- RNA polymerase
virion RNA cannot serve as mRNA
enveloped
What is the status of the
Nucleic Acid
Polymerase
and reason why in
reovirus
segmented double-stranded RNA
RNA-dependent- RNA polymerase
virion RNA cannot serve as mRNA
non-enveloped
What is the status of the
Nucleic Acid
Polymerase
and reason why in
retrovirus
two identical +single-stranded RNA
RNA-dependent DNA polymerase (reverse trans- criptase)
to make a DNA transcript of virion RNA
Enveloped
What is the status of the Nucleic Acid Polymerase and reason why in adenovirus herpes virus
linear double- stranded DNA
no pol
uses host enzyme to make mRNA
adeno is non-enveloped
herpes is enveloped
What is the status of the
Nucleic Acid
Polymerase
and reason why in
poxvirus
linear double- stranded DNA
DNA-dependent- RNA polymerase
cannot use host cell mRNA synthesizing enzymes because it replicates in the cyto- plasm
Pox: non-enveloped and enveloped
What is the status of the
Nucleic Acid
Polymerase
and reason why in
hepatitis B virus
circular double- stranded DNA with some single- stranded patches
reverse tran- scriptase (generally misnamed “DNA polymerase”)
must insert into host DNA
Enveloped
What is the status of the
Nucleic Acid
Polymerase
and reason why in
parvovirus
single-stranded DNA No pol uses host enzymes to make single- stranded genome into double-stranded DNA and to make mRNA Non-enveloped
What are the viruses with a
Respiratory route of infection?
rhinoviruses (often finger-to-nose) influenza viruses parainfluenza viruses mumps virus measles virus rubella virus varicella-zoster virus smallpox virus adenovirus parvovirus B-19
What are the viruses with GI route of infection?
polioviruses Coxsackie viruses ECHO viruses hepatitis A virus hepatitis E virus Enteric adenovirus Norwalk virus rotaviruses that cause diarrhea in infants enteric adenoviruses
What are the virus with skin contact route of infection?
papilloma viruses that cause cutaneous warts
herpes simplex virus type 1 molluscum contagiousum virus
What are the virus with venereal route of infection?
hepatitis B virus hepatitis C virus (probably) hepatitis D virus herpes simplex virus type 2 HIV -1 papilloma viruses that cause genital warts (at least you got something out of it)
What are viruses with transplacental route of infection?
rubella virus cytomegalovirus HIV -1 parvovirus B-19 varicella-zoster virus lymphocytic choriomeningitis virus (LCMV)
What are viruses with perinatal route of infection?
herpes simplex
hepatitis B virus
hepatitis C virus (probably) hepatitis D virus
HIV -1
What are viruses with breast milk route of infection?
HIV cytomegalovirus
