Final Review Flashcards
MC ADR with interferons
HA in 75%
Depression in 60%
Ribavirin can be used to treat Hepatitis ___
C
Timeline for protease inhibitors in treatment of Hep C
Telaprevir (Incivek) first 12 wks then stopped
Bocepravir (Victrelis) week 4 and onward
*always with ribavirin * peginterferon
recommended regimen for treatment of HIV/AIDS
viread +emtriva= Truvada
Isentress
What herpres medication can be PO, topical, or IV?
Acyclovir
Prevention of RSV with
Palivizumab (Synagis)
Prevention of rotavirus with
RotaTeq
live, oral pentavalent vaccine
3 dose regimen given 6-32weeks
multidrug resistant TB can use
Bedaquin (Sirturo)
What TB drug carries risk of optic neuritis?
Ethambutol
Active TB treatment profile
Rifampin x9m
Isoniazide x9m
Pyrazinamide x8w
Ethambutol x8w
Chloroquine is a
4-Aminoquinoline
Quinine sulfate & mefloquine are
4-Methanolquinolones
Primaquine is an
8-Aminoquinolone
Malarone is a
anti-folate
Antimicrobials that can be used as antimalarials
Tetracycline
Doxycycline
Clindamycin
MOA of metronidazole
interacts with DNA and loss of helical structure
What should be done when using Amphotericin B
pretreat with acetaminophen and corticosteroid
Mineralcorticoids include
Deoxycorticosterone (Percoten V)
Fludrocortisone (Florinef)
Only notable s/e of adrenergic agonists
Mirabegron (Myrebetriq)
HTN
watch for QTC elongation in pts with hx
antimuscarinics/anticholinergics worsen what type of urinary incontinence
over flow
Don’t use antimuscarinics in
GI obstruction
peptic ulcer disease
asthma
parkinsons
….ateride
5 alpha reductase inhibitor
….nafil
Tadalafil (Cialis)
Phosphodiesterase 5 inhibitor
blue vision associated with Viagra and phosphodiesterase 5 inhibitor class is dt
PDE5 Inhibitor
Tamoxifen (Nolvadex) is a
selective estrogen receptor modulator
Anastrozole (Arimidex) is a
aromatase inhibitor
Name an anti-HER2 agent
Tratuzumab (Herceptin)
Lapatinib (Tykerb)
Pertuzumab (Perjeta)
who is a candidate for aromatase inhibitor
not if intact ovaries!
good for post-menopausal women
notable ADR of ribavirin/ribasphere
hemolytic anemia
name an neuraminidase inhibitor for PO and inhalation routes respectively
PO: Oseltamivir (Tamiflu)
Inhalation: Zanamivir (Relenza)
Black box warning for Telaprevir (Incivek)
what would you be treating?
SJS
Hep C, first 12 weeks in combo with peginterferon & ribavirin
In general HIV/AIDS drugs commonly interact with other drugs via
CYP3A(4)
Generally best vehicle for derm
ointments
-oil in water emulsions MC
Dermatologic topical corticosteroid affects
antiinflam
immunosupression of humoral factors
Antiproliferative
Vasconstriction
Most potent corticosteroids
Class 1:
Clobetasol proprionate
Diflorasone diacetate
Halobetasol proprionate
What diseases are highly responsive to corticosteroids
Psoriasis (intertriginous)
atopic dermatitis (esp kids)
seborrheic dermatitis
Intertrigo
Adapalene cream is a
retinoid
First line treatment for acne
Benzoyl peroxide
ADRs of benzoyl peroxide
Peeling Stinging Dryness Erythema Contact dermatitis
Antibiotics for treatment of burns
Mafenide
*Silver sulfadiazine
