final questions Flashcards

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1
Q

1-Regarding Bortonella henseloe , which of the following is most accurate ?

A. Bartonella henselae is an anaerobic , spare - forming , gram - positive rod

B. The natural habitat of Bartonella henselae is the cat’s mouth

C. Bartonella henseloe causes cellulitis in immunocompromised patients such as AIDS patients

D. Goats and sheep are natural reservoirs of Bartonello henselae

A

B. The natural habitat of Bartonella henselae is the cat’s mouth

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2
Q

2-Different Salmonella serotypes use different mechanisms to invade the host cell ; which Salmonella serotype uses T3SS for invade the host cell

A. Salmonella enterica
B. Typhoidal serotype
C. Non - Typhoidal serotype
D. All of them

A

B. Typhoidal serotype

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3
Q
3-Which pathotype of E.coli cause non - toxin mediated watery diarrhea 
A. Diffusely adherent E. coli ( DAEC ) 
B. Enteroaggregative E. coll ( EAEC ) 
C. Enteropathogenic E. coli ( EPEC ) 
D. enterohemorrhagic E. coll ( EHEC ) 
E. Enteroinvasive E. coli ( EIEC )
A

C. Enteropathogenic E. coli ( EPEC )

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4
Q

4-Which bacterial pathogen is causative agent of neonatal meningitis and sepsis :
A. a - Hemolytic Streptococci - Streptococcus pneumoniae
B. Viridance group Streptococcl C
C.Group A Streptococci - Streptococcus pyogenes
D. Group B Streptococci - Streptococcus agalactiae

A

D. Group B Streptococci - Streptococcus agalactiae

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5
Q

5-select the pair of bacteria which produces exotoxins with protease activity cleave proteins involved in mediator release from the neurons?

A- Bacillus and Rocillus cereus
B- Clostrichum perfringens and Staphylococeus aureus
C- Clastridium tetoni and Bacillus anthracis
D- Clostridium botulinum and Clostridium tetani

A

D-Clostridium botulinum and Clostridium tetani

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6
Q

6-Select Incorrect statement

A- Actinomys israelii is an anaerobic rod found as part of the normal flora in the mouth.

B- Both Actinomyces and Nocardia are branching , filamentous tods.

C- Actinomyces and Nocardia Infections are usually diagnosed by detecting a significant rise in antibody titer.

D- Nocardio osteroides are weakly acid fast and causes infections primarily in immunocompromised patients.

A

C- Actinomyces and Nocardia Infections are usually diagnosed by detecting a significant rise in antibody titer.

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7
Q

7- Among the causative agents of brucellosis which statement is correct ?

A. The natural reservoirs of Brucellae are small rodents

B. Brucellae are obligate intracellular parasites that are usually identified by growth in human cell culture

C. Brucellae infect reticuloendothelial cells in the liver , spleen , and bone marrow

D. Brucellae are transmitted primarily by tick bite

A

C. Brucellae infect reticuloendothelial cells in the liver , spleen , and bone marrow

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8
Q

8-From the following statements select incorrect one :

A. Peptidoglycan has a backbone composed of alternating units of muramic acid and acetylglucosamine

B. Peptidoglycan is thinner in gram - positive than in gram - negative cells

C. Peptidoglycan can be degraded by lysozyme

D. Peptidoglycan has Cross - links between the tetrapeptides involve d-alanine .

A

B. Peptidoglycan is thinner in gram - positive than in gram - negative cells

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9
Q

9-Each of the following statements concerning Corynebacterium
diphtheriae is correct EXCEPT:
(A) Corynebacterium diphtheriae is a gram-positive rod that does
not form spores.
(B) Toxin production is dependent on the organism’s being
lysogenized by a bacteriophage.
(C) Diphtheria toxoid should not be given to children younger
than 3 years because the incidence of complications is too
high.
(D) Antitoxin should be used to treat patients with diphtheria

A

(C) Diphtheria toxoid should not be given to children younger
than 3 years because the incidence of complications is too
high.

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10
Q

10-Each of the following statements concerning resistance to antibiotics is correct EXCEPT:
(A) Resistance to aminoglycosides can be due to phosphorylating enzymes encoded by R plasmids.
(B) Resistance to sulfonamides can be due to enzymes that
hydrolyze the five-membered ring structure.
(C) Resistance to penicillins can be due to alterations in binding
proteins in the cell membrane.
(D) Resistance to cephalosporins can be due to cleavage of the
β-lactam ring

A

(B) Resistance to sulfonamides can be due to enzymes that

hydrolyze the five-membered ring structure.

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11
Q

11-Which pathogenic bacteria produce Toxic shock syndrome toxin ( TSST ) which causes the release of large amounts of interleukins : interleukin - 1 , interleukin - 2 , and TNF.

A. Bacillus anthracis 
B. Streptococcus spp . 
C. Corynebacterium diphtherio 
D. Staphylococcus aureus . 
E. Clostridium perfringens
A

D. Staphylococcus aureus .

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12
Q
  1. Select pathogenic bacteria that are anaerobic, gram-positive spore-forming rods, that produce two exotoxins, both are involved in the pathogenesis of pseudomembranous colitis?

A. Clostridium perfringens

B. Clostridium difficile

C. Bacillus cereus.

D. Corynebacterium diphtheria

E. Listeria monocytogenes

A

B. Clostridium difficile

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13
Q
  1. Select the pair of diseases that are caused by Staphylococcus aureus
    A. Pyogenic and granulomatous inflammation

B. Toxin-mediated and granulomatous inflammation

C. Pyogenic and pus-forming inflammation

D Pyogenic and Toxin mediated disease

A

D Pyogenic and Toxin mediated disease

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14
Q
  1. Regarding Mycoplasma pneumonia which one from the listed statements is not true

A. Pneumonia caused by M. pneumonia is associated with a rise in the titer of cold
agglutinins

B. Pneumonia caused by M. pneumonia occurs primarily in immunocompetent individuals

C. Pneumonia caused by M. pneumoniae is an “atypical” pneumonia

D. Mycoplasma pneumonie cannot be cultured in vitro because it has no Cell wall

A

D. Mycoplasma pneumonie cannot be cultured in vitro because it has no Cell wall

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15
Q
  1. Regarding the chlamydiae spp. which statement is not true:

A. Chlamydiae are strict intracellular parasites becaUse they cannot synthesize sufficient Atp

B. Chlamydiae possess both DNA and RNA and are bounded by a cell wall

C. Most chlamydiae are transmitted by arthropods

D. Chlamydiae are strict intracellular parasites because they cannot synthesize sufficient adenosine triphosphate (ATP)

A

C. Most chlamydiae are transmitted by arthropods

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16
Q
  1. All of the following statements concerning Clostridium perfringens is correct EXCEPT:
    A. Clostridium perfringens causes gas gangrene

B. Clostridium perfringens causes food poisoning

C. Clostridium perfringens produces an exotoxin that degrades lecithin and causes necrosis and hemolysis

D. Clostridium perfringens is a gram-negative rod that does not ferment lactose

A

D. Clostridium perfringens is a gram-negative rod that does not ferment lactose

17
Q
  1. Regarding the classification of streptococci which statement is incorrect:

A. Enterococci are group D streptococci and can be classified by their ability to grow in
6.5% sodium chloride

B. Viridans streptococci are identified by Lancefield grouping, which is based on the C carbohydrate in the cell wall

C.Although pneumococci and the viridans streptococci are a-hemolytic, they can be
differentiated by the bile solubility test and their susceptibility to optochin.

D. Pneumococci (Streptococcus pneumonia) are a-hemolytic and can be serotyped on the
basis of their polysaccharide capsules.

A

B. Viridans streptococci are identified by Lancefield grouping, which is based on the C carbohydrate in the cell wall

18
Q
  1. Regarding Gram-positive cocci select Catalase positive and Coagulase negative bacterial species:

A. Staphylococcus aureus and Staphylococcus epidermidis

B. Staphylococcus aureus and Staphylococcus saprophyticus

C. Staphylococcus epidermidis and Staphylococcus saprophyticus

D. Staphylococcus aureus and Clostridium perfringens

A

C. Staphylococcus epidermidis and Staphylococcus saprophyticus

19
Q
  1. Which pathogen produce exotoxin that kills cells by Inhibiting elongation factor-2, resulting in the inhibition of protein synthesis?

A. Clostridium botulinium

B. Clostridium tetani

C. Corynebacterium diphtherlae

D. Bacillus anthracis

E. Clostridium difficile

A

C. Corynebacterium diphtheriae

20
Q
  1. Regarding the Mycobacterium leprae which following statements is not true

A. Loss of sensation due to nerve damage is often seen in leprosy

B. The organism will grow on bacteriologic media in 3 to 6 weeks

C. In lepromatous leprosy, large numbers of organisms are usually seen in acid-fast-stained smears

D. Prolonged therapy (9 months or longer) is required to prevent recurrence

A

B. The organism will grow on bacteriologic media in 3 to 6 weeks

21
Q
  1. Which one of the listed organisms causes atypical pneumonia

A. Haemophilus influenza

B. Legionella pneumophila

C. Bordetella pertussis

D. Acinetobacter baumannil

A

B. Legionella pneumophila

22
Q
  1. Regarding gram negative rods which statement is not true

A. Disease caused by Haemophilus influenzae is most often due to strains possessing a type b polysaccharide capsule

B. Legionella pneumophila infection is acquired by inhalation of aerosols from environmental
water sources

C. Whooping cough, which is caused by Bordetella pertussis, is on the rise because changing antigenicity of the organism has made the vaccine relatively ineffective

D. Pseudomonas aeruginosa causes wound infections that are characterized by blue-green pus as a result of pyocyanin production

A

C. Whooping cough, which is caused by Bordetella pertussis, is on the rise because changing antigenicity of the organism has made the vaccine relatively ineffective

23
Q
  1. Which pathogen from the listed organisms are less likely to be transmitted during gestation or at birth ?

A. Treponema pallidum

B. Chlamydia trachomatis

C.Haemophilus influenzae

D. Neisseria gonorrhoeae

A

C.Haemophilus influenzae

24
Q
24. Choose a disease that is not zoonotic?
A. Plaque
B. Tularemia
C. Tuberculosis
D. Brucelosis
A

C. Tuberculosis

25
Q

25, Which pathogenic bacteria produce exotoxins, that causes hemolyicuremiesyndrome(HUS)

A. E, coli and Vibrio cholerae
B. Salmonella Typhi
C. Salmonella enterica
D.Shiga toxin producing E. coli 0157 serotype

A

D.Shiga toxin producing E. coli 0157 serotype

26
Q
26. Choose a zoonosis that is not transmitted by arthropod vectors?
A.Brucellosis
B. Epidemic typhus
C. Lyme disease
D. Plague
A

A.Brucellosis

27
Q
  1. Regarding Mycoplasma pneumonia which one from the listed statements is not true

A. Pneumonia caused by M. pneumoniae is associated with a rise in the titer of cold agglutinins

B Mycoplasma pneumonia cannot be cultured in vitro because it has no cell wall

C. Pneumonia caused by M. pneumoniae is an “atypical” pneumonia

D. Pneumonia caused by M. pneumoniae occurs primarily in immunocompetent individuals

A

B Mycoplasma pneumonia cannot be cultured in vitro because it has no cell wall

28
Q
  1. Regarding Neisseria meningitidis select incorrect statement

A. it has a polysaccharide capsule that is antiphagocytic

B It produces an exotoxin that stimulates adenylate cyclase

C. It is an oxidase-positive, gram-negative diplococcus

D. It contains endotoxin in its cell wall

A

B It produces an exotoxin that stimulates adenylate cyclase

29
Q
  1. Find bacterial species which produce exotoxins that act by ADP-ribosylation?

A. Escherichia coli and Streptococcus pyogenes

B. Enterococcus faecalis and Mycobacterium tuberculosis

C. Corynebacterium diphtheria and Escherichia coli

D. Clostridium perfringens and Staphylococcus aureus

E. Clostridium tetani and Bacillus anthracis

A

C. Corynebacterium diphtheria and Escherichia coli

30
Q
  1. After a cat bite, a person develops a red, hot, painful, swollen lesion at the site of the bite,
    which quickly spreads down the arm. Which pathogenic bacteria can cause this cellulite?
    A. Bartonella henselae
    B. Brucella melytensis
    C. Francisella tularensis
    D. Pasteurella multocida
A

D. Pasteurella multocida