Final exam study guide Flashcards
What does IACUC stand for?
Institutional Animal Care and Use Committee
What task is NOT a function of the IACUC?
Assist with writing the basic science portions of a grant application
What organization is responsible for monitoring institutional compliance with PHS Policy?
Office of Laboratory Animal Welfare
Which of the following institutions must follow PHS guidelines for animal research?
All institutions that accept PHS funding
Which of the following is the role of the AAALAC?
To conduct voluntary evaluations of institutional animal care and use programs
Which of the following is helpful to the IACUC when reviewing an animal protocol?
Use of a flowchart to illustrate complex experimental designs
Which of the following statements concerning selection of species for research is FALSE?
vertebrate species should be used instead of invertebrates whenever possible
Which of the following statements about using a statistical analysis to justify animal numbers is TRUE?
a statistical analysis should be used whenever possible
The three R’s of Russell and Burch stand for what?
replacement, reduction, refinement
Which of the following is NOT an example of reduction?
The use of a new anesthetic that provides better induction and a shorter recovery period
Which of the following is an example of refinement?
the use of a new blood collection technique that causes less pain and distress
The Animal Welfare Regulations require the IACUC to do what two things regarding alternatives?
ensure that the PI has considered alternatives to painful or distressing procedures, and review a written assurance that alternatives are not available
What is the primary mission of the Animal Welfare Information Center (AWIC), a part of USDA?
to provide assistance with alternatives and database searches
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area?
performing or sponsoring research into alternatives to animal use for research and testing
Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments?
unnessecary duplication is not allowed
What is the basis for pain/distress classification system used by most institutions?
USDA pain/distress categories
Which of the following activities would exclude an animal from USDA category B?
blood collection
USDA pain/distress categories
B no pain distress—> E unrelieved pain/distress
Which of the following activities would exclude an animal from USDA category D?
studies in which animals are allowed to die without pain relief
