FINAL EXAM REVISIONS - LEARNING OBJECTIVE Flashcards
What does Haematoxylin stain? What Colour?
Stains the Nucleus (Nuclei and Lymph node) dark blue or Purple
What does Eosin stain? What Colour?
Stains the Cytoplasm (Proteins - Muscle or cytoplasm with little nucleus) pink
Define Cellular Differentiation
- Features in cell that show it has a function and structure
- It is a specialised Cell
What is a specialised Cell?
A Nucleus that contains microvilli attached
What is an undifferentiated cell?
- A cell that does not have a function
- It is an Unspecialised cell
What is an unspecialised cell
- It is a Stem Cell
- Just a Nucleus
What is a Gastrula made up of?
Ectoderm, Germ Cells, Mesoderm, Endoderm
Does a change in Environment cause a change in a cell?
Yes, in each cell there is DNA and specific strands can be turned on and turned off based on the surrounding environment
Environment is a determinant in what a cell can become.
Cell considered Epithelial?
Skin Cells GIT cells Reproductive Cells Urinary Tract Cells Lining of Exocrine ducts Liver Cells Kidney Cells Respiratory cells Pancreas Cells Glandular Epithelial Cells
Types of Epithelial Cells? There’s 7…
Simple Squamous Stratified Squamous Simple Cuboidal Simple Columnar Pseudo Stratified Transitional Stratified Cuboidal/Columnar
Feature of a Simple Squamous Epithelium:
- Single Layer
- Cytoplasm usually appears thinner than Nuclei
- Allows gases, ions and small molecules to pass through
What are the 3 types of cells:
Labile
Stable
Permanent
What are Labile Cells
Continuously Dividing
Epithelial
Haemopoietic Stem Cells
What are Stable Cells
Divide only when required - growing tissue back
Epithelial
Smooth Muscle Cells, Fibroblasts and endothelial Cells
What are Permanent Cells?
Non-Dividing Cells
Cardiac Cells
Skeletal Myocytes
CNS Neurons
What is proliferation? Explain the process
The rapid division of a cell
DNA is unwined and replicated during the cell cycle if stimulated - G0 is cell cycle arrest - stable cells
Stages of the Cell Cycle
During the cell cycle, cells become labile
Stages: G1, S, G2, Mitosis, Cytokinesis
What do tissues need?
Nerve Innovation Blood and Lymphatic Supply and removal: - Gases, Hormones and Growth Factors Defence against invasions: - Skin/Epidermis (fat) - GIT - Urogenital - Respiratory
What do Cells Need?
Functional Plasma Membrane (Skin) Ability to make RNA and Proteins Ability to Copy and repair DNA Functional cytoskeletal proteins Energy (ATP) Antioxidant Defences Ability to remove waste including proteins Ability to repair or destroy redundant and damaged organelles The correct temperature, pH, etc.
How do cells communicate?
Through distant cells using chemicals released into the blood such as hormones
Through Neighbouring cells and connecting tissue (Acting in a paracrine matter)
- Epithelial Cells like to be attached to their neighbours and membranes beneath them
What is a Paracrine process?
Communication with neighbouring cells directly
What is an Autocrine process?
The cell communicates with itself
What is an Endocrine process?
The cells communicates over distance through blood
Mitochondria
Surrounded by a double membrane Generate ATP Full of Oxidative Enzymes Induces cell death Possibly drives differentiation