Final Exam Review ---Glomerular Diseases

Question 1

The 4 glomerular disorders with decreased C3 and C4, and are they nephritic or nephrotic :

Answer 1

All nephritic

1) Post infectious GN — decreased C3, possible decreased C4
2) Proliferative Lupus Nephritis: decreased C3 and C4
3) MPGN— decreased C3, possible decreased C4

Question 2

Which GD has low C3, normal C4?

Answer 2

C3 glomerulopathy

Question 3

What is the serology for Post infectious GN?

Answer 3

Anti-DNase B

ASO

Question 4

What is the serology for Prol. Lupus Nephritis?

Answer 4

ANA
dsDNA
anti-Smith

Question 5

Serology for MPGN?

Answer 5

Hep C Ab+
CRYOGLOBULINS
SPEP
Blood cultures

Question 6

Serology of C3 glomerulopathy?

Answer 6

mutations or antibodies to complement

Question 7

3 Glomerular disorders with normal C3 and C4

Answer 7

Iga A Nephropathy
Alport Syndrome
Pauci-Immune GN