Final Exam Review Flashcards
Vitamins
Organic molecules
Two types of vitamins
Water and fat soluble
Water-soluble vitamins examples
C and D
Fat soluble vitamin examples
ADEK
Water-soluble vitamins characteristics
- absorbed best in the stomach
- transported to intestinal cells via facilitated diffusion or active transport
- transported to the body by binding to blood bound proteins
- too much of it gets excreted in pee
Fat-soluble vitamins characteristics
- absorbed with the help of fat
- absorbed in intestinal cells with the help of chylomicrons w/ lipids
- transported around the body through lipoproteins/transport proteins
- too much of it gets stored in the body
Vitamin Bs
- involved in enzyme activity (coenzymes)
- burns CHO, proteins and fat
B1
thiamin
B2
riboflavin
B3
niacin
B5
pantothenic acid
B6
pyridoxine
B7
biotin
B9
folate/folic acid
B12
cobalamin
Grains
B1 B2 B3 B6
Fruits and Veggies
B2 B6 Folate
Milk
B2 B12
Meats
B1 B2 B3 B12 folate
Flour
Iron, folic acid, thiamin, riboflavin, niacin
Fortification
adding nutrients to foods that generally don’t have that nutrient
Enrichment
adding nutrients back to food in which they have lost from processing
examples of fortified foods
iodine w/ salt
calcium in oj
milk w/ vitamin D
Thiamin (B1)
- burns glucose for energy
- carbs metabolism
- enriches grains
Example of thiamin
pork
Not enough thiamin
beriberi - nerve damage, lethargy, depression, CVD, fatigue
Wernike-korsakoff syndrome
caused by a combo of absorption problems and poor quality diet
folic acid
synthetic form of folate used to fortify foods
Vitamin C
“ascorbic acid”
- water soluble and travels around freely in the blood
- coenzyme that makes collagen
- protects DNA and lipids
- an antioxidant
Collagen
- makes up connective tissue
Bile Acid
- neurotransmitters, hormones
Why can’t humans make vitamin C?
we don’t have the right enzymes to make it out of glucose
Oxidation
taking of electrons by free radicals
- product of metabolism
- oxygen burned turns free radicals during the process of energy metabolism
what can be oxidized?
cell membrane phospholipids, DNA, LDL, proteins
more oxidation increases the risk of
heart disease, cancer, diabetes, arthritis, cataracts, alzheimers, kidney disease
antioxidants
chemicals that decrease the adverse effects of free radicals by donating their electrons and neutralizing them into less harmful substances
What can destroy Vitamin C
Baking and oxygen, boiling water
What can retain VC?
steaming, roasting, stir-frying
Scurvy
Little or no VC
- bleeding gums, lose teeth, hemorrhaging, impaired wound healing, swelling, bone pain
Where is Vitamin A absorbed?
small intestine with fat
Vitamin A roles
night vision, cell differentiation, growth regulation, maintenance of epithelial tissues, immune system, development of embryo
Where is Vitamin A found?
preformed from animal products/supplements
precursor form from plant foods
Precursor to Vitamin A
cartenoid
Preformed Vitamin A compound
Retinoid
Beta-carotene
yellow, orange and red pigments
- a carotenoid
- precursor
- an antioxidant
- prevents cancer, heart disease, macular degeneration, cataracts
RDA Vitamin A
900 men, 700 women
Where does most of our Vitamin A come from?
PREFORMED!
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Vitamin A deficiency
can cause night blindness, dry eyes, blindness, poor growth
Too much Vitamin A
loss of appetite, blurred vision, pain, nausea, liver/organ damage, birth defects
Vitamin E
- antioxidant
The more PUFA you eat…
the more antioxidants you will need to protect the fats from oxidation
What is Vitamin E destroyed by?
Oxygen, light, metals, heat
Why is Vitamin E deficiency rare?
Our body stores it
Vitamin E deficiency
- high risk of CVD
- nerve damage
- hemolytic anemia
Vitamin E and CVD
- reduced oxidation LDL
- reduced inflammation of the blood vessels which can lead to plaque flaking off
- reduces platelet stickiness
Fluid
molecules are far enough apart that they can slide past each other
What % fluid is our body
60
Where is fluid in our body?
blood, GI tract, lining organs, intracellular, extracellular
What are fluids made of
electrolytes
What are electrolytes
dissolved minerals (ions) +/- charge
Major electrolytes
magnesium, sodium, potassium, chloride, phosphorus, calcium
What do fluids do?
- Transports nutrients and waste
- dissolves substances like carbs, AA, water soluble vitamins, minerals, meds
- water insoluble substances are transported with the help of chylomicrons
- moistens us (saliva, tears, mucus)
- maintains body temperature
- chemical reaction
- protects
cerebrospinal fluid
cushions the brain
amnionic fluid
protects the fetus
hydrolysis
water needed to break 2 molecules
condensation
water released when 2 molecules join
where do we get our water?
75-80% comes from beverages
20-25% comes from foods
some comes from metabolism ‘
making triglycerides and peptide bonds
how do we lose water?
pee, poo, sweat, breath
Thirst
hypothalamus signals it
stimulus of thirst - high concentrations of solute in blood, low blood volume/pressure, dryness in mouth
problem with thirst mechanisms
gets worse as we age
Regulation of water losses
- you don’t pee
- antidiuretic hormone gets released and tells kidneys to keep as much water as possible from being lost in the urine
How much fluid do we need
women 2.7 L
men 3.7 L
Dehydration
excreting more water than you take in
how is dehydration measured?
change in body weight
when do symptoms of dehydration appear
1-2% decrease in body weight
- loss of appetite, crankiness, headache, faintness, tiredness, dry eyes and mouth, dark urine
Moderate to severe dehydration % of water loss
3-5%
Moderate to severe dehydration results in
dizziness, sleepiness, nausea, headaches, decreased concentration
- greater than 7% can lead to delirium
10-20% can cause death
who’s susceptible to dehydration
athletes, children, older athletes
overhydration also know as
water intoxication
what is overhydration caused by?
too much fluid without enough sodium
what can overhydration lead to?
seizures, coma and death
define electrolytes
helps regulate fluid balance through osmosis