Final Exam Resp (pgs. 77-83) Flashcards
1
Q
% of O2 dissolved in blood
A
1.5%
2
Q
% of O2 bound to Hb
A
98.5%
3
Q
what contributes to Po2?
A
only unbound O2
4
Q
What is at the center of Hemoglobin?
A
- Iron
5
Q
Color difference of blood when lots of O2 bound vs little O2 bound
A
- More –> bright red
- Less –> dark red
6
Q
how many binding sites for O2 on Hb?
A
4
7
Q
Why does the hemoglobin dissociation curve have a steep region?
A
-cooperative binding makes it so once one O2 binds, easier for the next O2 to bind
8
Q
point of plateau region in hemoglobin disassociation curve?
A
- reserve of O2, if Po2 goes way down (not breathing as much), still at almost 100% hemoglobin saturation
9
Q
Sleeping and Po2
A
- when sleeping we don’t ventilate as well, plateau protects Hb saturation
10
Q
O2 pickup in lungs
A
- from alveolus to dissolved O2 into RBC then binds to Hb
11
Q
O2 delivery in tissues
A
- O2 unbound from Hb, into RBC, into plasma, into interstitial fluid into cells
12
Q
what O2 moves into cells first?
A
- dissolved O2
13
Q
Effect of temp on O2 transport
A
- less bound Hb at higher temps, allows for easier unloading at active tissues (higher temp)
14
Q
What shift of Hb curve occurs when temp increases?
A
- right shift
15
Q
effect of change in pH on O2
A
- right shift: higher acidity (lower pH)
- affinity for O2 down at lower pH, unloads O2 easier
