Final Exam Questions Flashcards
Name the species Most commonly affected by white nose syndrome in bats
Little brown bats Northern Long eared bats Tricolored bats
Which blood factor triggers anthrax spore germination?
L – alanine in serum
In which cells do anthrax bacteria grow?
Macrophages
In primates, where the gross findings associated with measles infections?
Facial edema Rash
Lyssaviruses. Which glycoprotein is responsible for attachment and pathogenicity?
G glycoprotein
Which genotype causes rabies in North America
Genotype one
Which species in North America is most commonly found positive for rabies virus?
Big brown bats
Which species is responsible for the majority of the Zoomotic rabies transmission in North America?
Silver haired Bats
In carnivores infected by canine distemper virus, what is the most common secondary infection?
Toxoplasma
Which type of virus causes Aleutian disease in ferrets and mink?
Parvovirus
What are the two major diseases caused by pesti virus infection?
BVD Classical swine fever
In black footed ferrets infected with canine distemper virus, what is the most common secondary infection?
Coccidiosis
Which mineral is necessary for anthrax spore dormancy and survival
Calcium
In dogs infected with canine distemper virus, what is the most common secondary infection?
Pneumocystis carnii
What are the four broad disease syndromes associated with retroviruses?
- Malignant tumors 2. Wasting disease 3. Neuro disease 4. Immunodeficiency
Important hosts of Tularemia
Lagomorphs, rodents including voles, muskrats, lemmings, hamsters, beavers
What are the two important avian paramyxovirus
Newcastle’s disease Avian influenza
Which avian diseases are associated with birdfeeders?
Avian pox Salmonella
Differential diagnoses for multifocal, small white spots on liver in mammals
Tyzzer’s disease – Clostridium piliforme Yersiniosis – Yersinia pseudorubedculosis Tularemia - Francisella tularensis Less common salmonella/E. coli septicemia
Describe the pathogenesis resulting ultimately in death from rabies
Decrease nerve input + apoptosis = organ dysfunction = death
What key feature distinguishes Tyzzer’s Disease from Tularemia and Yersiniosis?
No splenic lesions
Name the molecular typing used for Mycobacterium
Spoligotyping PCR of 43 conserved segments
Why are birds resistant anthrax?
Body temperature is too high for replication
Describe anthrax bacteria morphology
Gram-positive Long rod in short chains
What triggers anthrax sporulation?
Decreased nutrients Decreased water
Why do anthrax spores congregate after flooding?
Hydrophobic surface layers – increased buoyancy – moves up the water table and from water onto vegetation
How many known neurotoxins are there for avian botulism? Which are most common?
7 Type C Type E
CWD – how does dose affect incubation period?
Increased dose = decreased incubation.
What species is responsible for the majority of Canadian zoonotic cases of Tularemia?
Snowshoe hare – hunters
Differential diagnoses for 1. myocardial necrosis/infarct
- Hemorrhage
- Lead poisoning West Nile virus
- Duck Plague & Avian cholera