Final Exam Q&A Flashcards
What are general contraindications to vaccines?
- Severe reaction, e.g., anaphylaxis, after a previous dose or to a vaccine component
- Vaccines can be given even if egg allergy
What vaccines contraindicated in pregnant women, severe immunodeficiency (e.g., hematologic and solid tumors, chemotherapy, congenital immunodeficiency or long-term immunosuppressive therapy) and in HIV infection (CD4+ count < 200)?
- MMR
- VAR
- HZV
- HPV
- Influenza (LAIV)
- TB
Wha general approaches to management parents who refuse vaccinations for their child?
- Establishing a positive dialogue
- Identifying specific parental concerns
- Providing education targeted to those concerns
- Maintaining a relationship with the family
- Making every effort to follow the recommended immunization schedule
What are non-pharm interventions for scabies & lice?
- Removal nits using specially designed combs after pharm treatment
- Wrap hair in vinegar-soaked towel for 30-60mins
- Launder all personal belongs in hot water
- Soak combs & brushes in disinfectant solution (or rubbing alcohol) or in hot water
What is the first line treament for folliculitis and furuncles?
- Usually self-limiting
- Hot compresses and anti-septic cleaner may be beneficial
- Systemic therapy not generally required
When are live, attenuated vaccines contraindicated?
- Pregnancy
- Severe immunodeficiency (e.g., hematologic and solid tumors, chemotherapy, congenital immunodeficiency or long-term immunosuppressive therapy)
- HIV infection (CD4+ count < 200)
What is the second line treament for folliculitis and furuncles?
Topical therapy in less severe/localized cases
- Mupirocin 2% cream. Apply sparing TID
- Fusidic Acid 2% cream. Apply sparingly TID-QID. If covered with occlusive dressing, then daily or BID
Same 1st line as impetigo & bullous impetigo
What are the 1st and 2nd treament for carbuncles?
Carbuncles-Moderate-Severe (“c” for collection of furuncles and antiobiotics)
- 1st line: Cephalexin 500mg QID
- 2nd line: Cloxacillin 500mg QID OR Clindamycin 300-450mg QID
What is the 1st line and 2nd treatment for cellulitis – Uncomplicated: Mild (Adult & Child)?
- 1st line: Cephalexin 500mg QID; Children: 50-100mg/kg/day divided q6h
- 2nd line: Cloxacillin 500mg QID; Children: 50mg/kg/day divided q6h OR Clindamycin 300mg QID; Children: 25mg/kg/day
- Caused by S. aureus, Group A Strep
What does the post-exposure prophylaxis of immunocompetent persons who have not been previously immunized with rabies vaccine consists of?
- local wound treatment
- rabies immune globulin (20 IU/kg) given on day 0 with as much as possible infiltrated into and around the wound; and
- four 1.0 mL IM doses of rabies vaccine given on days 0, 3, 7 & 14
Post-exposure prophylaxis of persons previously appropriately immunized with rabies vaccine consists of:
- local wound treatment, and
- Two 1.0 mL IM doses of rabies vaccine given on days 0 and 3
- Rabies immune globulin should not be given to persons who have previously received appropriate rabies vaccinations
What are the health teaching for a patient with herpes simplex virus?
- consistent safer-sex practices
- risk of genital herpes from orogenital sex
- Identify barriers to prevention and the means to overcome them
- Genital HSV infection is not curable
- Natural history of the disease, emphasis on recurrent episodes, asymptomatic shedding & sexual transmission
- Antiviral therapy(Valacyclovir) for recurrent episodes may shorten duration of lesions, and suppressive antiviral therapy can ameliorate or prevent recurrent outbreaks
- inform their sex partner(s) that they have genital herpes.
- Have patient and sexual partner(s) get type-specific serologic testing
- Transmission of genital herpes can occur in asymptomatic shedding
- Abstain from sexual activity from the onset of prodromal symptoms until the lesions have completely healed
- Condom use
- Assess patients with genital herpes for other STIs and treat as needed.
- Discuss the risk of neonatal infection with all patients, including men.
- Genital herpes increases the risk of acquisition of HIV twofold
Treatment for herpes zoster should be initiated:
Within 24 hours of symptoms
Within 72 hours of onset of rash
Effective initiated at any time
Only effective for recurrent infections
- Within 72 hours of onset of rash
- Systemic antiviral nucleoside analogues (acyclovir, famciclovir, valacyclovir), initiated within 72 hours of rash onset, reduce the duration of viral shedding, acute pain and the appearance of new lesions
All oral antivirals are effective in reducing the time to healing of orolabial herpes simplex infection?
True
False
- False
- Valacyclovir may be more effective than acyclovir, and both are more effective than famciclovir
Which one of following is a first-line treatment of varicella zoster in an immunocompetent host?
valacyclovir 1000 mg PO TID x 7 days
valaclyclovir 500 mg PO TID x 7 days
gancyclovir 1000mg PO TID x 7 days
Zostrix 3gms topically BID
valacyclovir 1000 mg PO TID x 7 days
Which one of the following is a common side effect of the first-line agent in the treatment of herpes zoster are:
- GI upset and flatulence
- metallic taste and constipation
- rash and fatigue
- nausea and headache
nausea and headache
Which of the following products are recommended in the treatment of pain related to herpes zoster?
- Tylenol
- Ibuprofen
- Gabapentin
- Hydromorphone
- All the above
All the above
Which type of therapy is considered first line in the treatment of comedonal acne?
- Retinoic acid
- Topical retinoid therapy
- Acutane
- Clindamycine po
Topical retinoid therapy
What is the main side effect of topical retinoid therapy?
A) increase number of pimples before seeing improvement
B) greasy skin
C) skin irritation
D) scarring
C) skin irritation
What is the recommended dose of tetracycline as a systemic treatment for acne?
250 mg po daily, then 100mg daily for maintenance.
500 mg po bid, then 250 mg daily for maintenance
1000 mg po bid, then 500mg daily for maintenance
375mg po daily, continue for maintenance
500 mg po bid, then 250 mg daily for maintenance
Which of the following is contraindications of tetracycline?
comedogenic acne
age under 16 years
pregnancy
history of GI upset
pregnancy
Check all of the following that are known side effects of tetracycline:
GI irritation
photosensitivity
intracranial hypertension
rash
photosensitivity
GI irritation
intracranial hypertension
Topical clindamycin and erythromycin, used in combination with benzoyl peroxide, reduces the risk of bacterial resistance.
True or False?
True