Final Exam - All Drugs Flashcards

1
Q

Acetaminophen

A

fever, pain
Hepatotoxic, OD

Antidote= Acetylcysteine

<4g / day
avoid other Hepatotoxic meds

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2
Q

Anti Migraine

A

Ergotamine, Sumatriptan
aborts migraines

“DEV-T”
Dizzy
Ergotism/toxicity
Vasospasm
Teratogenic

Avoid CNS depressants, dependence

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3
Q

BETA 2 AGONIST

A

“BAM” - bronchodilator

Albuterol - short acting - rescue inhaler
T= tremor, toss/turn, tachycardia – dry mouth
use before exercise, rinse mouth

Formoterol - long acting
T, muscle cramp

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4
Q

anticholinergic

A

“BAM” - bronchodilator
Ipratropium
“Dry = can’t see, pee, spit, poop”
Hydrate

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5
Q

Methylxanthine

A

“BAM” - Bronchodilator
Theophylline “old school albuterol”
T= tremor, toss/turn, tachycardia
Toxicity: Seizures, arrhythmia, vomiting
monitor blood levels

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6
Q

CorticoSTEROIDS

A

“SLM” - anti inflammatory
Beclomethasone, Fluticasone (inhaled)
oral thrush, hoarse
rinse mouth

Prednisone (PO)
“ROIDS”
Rmbr to take w/ food
Oral thrush, Osteoporosis
Immunosuppress- taper (Cushing’s)
Die by hyperglycemia (3 P’s)
So many ulcers

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7
Q

Leukotriene Modifier

A

“SLM” - anti inflammatory
Montelukast
Mood, ABD pain
take PM, avoid NSAIDs

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8
Q

NSAID

A

pain, fever, inflammation

“NSAIDDS”
Not good for the body
Sticky clot
Asthma/bronchospasm
Increase bleeding
Don’t take on empty stomach
Dmg kidneys
Swelling heart (no HTN, heart disease)

“ASPIRIN”
ABD pain
Salicylate toxicity
Peptic ulcer
Increase bleed
Reyes
Itchy rash
Noise/Tinnitus

“NSIK”
Naproxen, Salicylate/ASA, Ibuprofen, Ketorolac (IV)

Antidote = Activated charcoal, gastric lavage

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9
Q

opioid agonist

A

Morphine
pain, sedation.
NARCSU, orthostatic hypotension
OD (pinpoint pupils, RR <12, vomit)
OD antidote = Naloxone
Avoid alcohol and CNS depressants; ↑ fiber and exercise.

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10
Q

PPI

A

-prazole
↓ acid
“PRONE”
Pneumonia
Rebound acid - taper
Osteoporosis
Never w/ NSAIDs
Eat AM before meals

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11
Q

H2 blockers

A

blocks aldosterone
↓ acid
“DINE*”
Dont drink, smoke, cafe
Increase liver dmg
Night med
Elderly - CNS
*GI Bleed

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12
Q

Bismuth

A

Coats stomach lining (to ↓ irritation, inflammation)
black tongue / stool = norm
Reyes, salicylism (tinnitus, dizzy)

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13
Q

Promethazine

A

For N/V
Sedation, OD (esp kids)
IV - Extravasation
Extra Pyramidal → Stop & Benadryl
Pt Ed: avoid other CNS depressants, don’t drive

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14
Q

ARBS / Angiotensin 2 blocker

A

“ARTAN”
Anti HTN
Rly high K+
Test pregnancy
Angioedema
No ACE or renal stenosis

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15
Q

direct renin blocker

A

Aliskiren
“BLAATH”
Blocks renin to ↓ BP
Low fat meals
Angioedema
Avoid ACE & ARB
Take same time daily
Hyperkalemia

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16
Q

beta blocker

A

“-LOL”
“Lull heart to Sleep”
“1 heart, 2 Lungs”
↓ HR and BP
Cardioselective= blocks BB in heart
non-Cardioselective= blocks BB in heart AND lungs

“RAT HM”
Rebound HTN- taper
Asthma / bronchospasm
Tachycardia
Hold if HR <60 / BP <90
Mask hyperglycemia

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17
Q

Thiazide diuretic

A

Hydrochlorothiazide
↓ BP
“RIGHT”
Review BP before
Increase Na+ and water excretion
Got hypokalemia
Hyperkalemia
Try avoiding anuria, sulfa allergy

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18
Q

ACE inhibitor

A

“-PRIL”
blocks angiotensin 1→2
“ACH”
Angioedema
Cough
Hyperkalemia

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19
Q

cardiac glycoside

A

Digoxin
↑ cardiac contraction, ↓ HR.
“DICA”
Digoxin toxicity (N/V, bradycardia, vision- halos)
Intake same time daily
Consistent K+
Apical HR- hold if <60

*Digoxin immune fab = antidote

20
Q

loop diuretic

A

Furosemide
“FOREST”
For ↓ BP
Ototoxic (tinnitus, hearing)
Review BP before
Electrolyte and K+ depletion
Stops sodium reabsorption
Take AM - nocturia

21
Q

Calcium Channel Blocker

A

Amlodipine
“-PINE”
stops calcium influx to ↓ BP
“CHANNER”
Cardiosuppression
Hypotension- hold BP <90
Avoid grapefruit
No digoxin
No Beta blocker
Edema- peripheral
Rebound HTN

22
Q

HMG-CoA Reductase Inhibitor

A

STATIN
↓ cholesterol
“HMG COA”
Hepatotoxic
Myopathy, rhabdo
GI
CAD, cholesterol
Overly dark urine
Avoid grapefruit

23
Q

Heparin

A

Enoxaparin
anti-coag to prevent clots
“ENOX-HP”
Examine aPTT
No bleeding pts
Osteoporosis
Xa and thrombin blocker
HIT (thrombocytopenia)
Protamine sulfate = antidote

24
Q

Warfarin

A

anti-coag to prevent clots
“VIT K”
Vit K blocker
INR (2-3)
Teratogenic
Killer necrosis
*antidote = Vit K

25
Penicillin / PCN
abx cell wall - bacteriacidal "-CILLIN" x Cef "NAAG" Nephrotoxic Anaphylaxis Abx teaching GI
26
Aminoglycoside
abx protein synthesis - bactericidal Gentamicin "Gents are NNEAT" "NNEAT" Nephrotoxic Neuromuscular blockade → OD, weak muscles Ears Abx teaching Trough - draw before next dose
27
Tetracycline
"-cycline" abx protein synthesis - bacteriostatic teeth → preg, <8y x dairy, iron "PHAG" Photosensitivity Hepatotoxic Abx teaching GI
28
Ketoconazole
anti fungal x ergosterol - cell membrane "QT WIG Hepato!" QT W/food Irregular period, gynecomastia GI Hepatotoxic
29
Antimicrobial Teaching
* Supra-Infections (oral thrush, c.diff, yeast) * non-hormonal Contraceptives * Complete Entire Course
30
fluoroquinolone
"flox" Ciprofloxacin x DNA gyrase "QT PAT X" QT Photosensitivity Abx teaching Tendon rupture! X preg, <18y
31
levothyroxine
for hypothyroidism "OH WAIT" Osteoporosis Hyperthyroidism Wait few hrs to eat Avoid pregnancy, kids (cancer), anti-coags, steroids, grapefruit Infertility Take on empty stomach, w/water, same time daily
32
Sx Hyperglycemia
"3 P's" Polyuria Polydipsia Polyphagia Dry mouth Blurred vision
33
sx Fluid Vol Overload / Hypervolemia
"WET LUNG" W — Weight gain E — Edema T — Tight skin (from swelling) L — Lung crackles U — Unable to breathe (SOB) N — Neck vein distension (JVD) G — Gurgling cough (pink frothy sputum)
34
HYPERTONIC dehydration
* Water loss > Electrolyte loss Causes: * Fever— increased RR → increased water loss; sweating * Polyuria— DM, diabetes insipidus, diuretic use * Drinking urine or seawater for survival If dehydration is not corrected, leads to renal injury from muscle breakdown and lactic acidosis
35
HYPERTONIC solution
* Fluid moves out of cells into ECF – cells shrink * “I need to get the fluid out of my soaked SOCK” * Severe hyponatremia: Pulls water and sodium back into ECF, where it belongs. * Overload of fluid in spaces where it doesn’t belong—pulls fluid out of cells, into ECF * Cerebral edema: Pulls fluid from brain cells to prevent herniation * Ketosis
36
Hyperkalemia
“PISO = Potassium inside, Sodium outside” * Major cation in ICF "K= Kardiac" * transmits nerve impulses—esp. in the HEART “MURDER” * Muscle weakness, ↓ Urine, Resp. Depression, cardiac contractility, EKG (wide PR, QRS / asystole, v-fib), ↓ reflex Avoid salt substitutes & blood transfusions
37
IV potassium safety
* Never IV bolus potassium → cardiac arrest! (on pump only) * Always verify that IV potassium is diluted never give as an IVP or fast bolus! * If pt has any potassium problems, must be on continuous EKG monitoring.
38
Angina: Stable vs. unstable
myocardial ischemia due to ↓ coronary blood flow Stable -short duration -pattern -better w/ rest and meds Unstable -long duration -unpredictable -not better w/ rest or meds Emergency!
39
Atherosclerosis
buildup of plaque in arteries, leading to ↓ blood flow and risk of MI or stroke
40
Chronic Kidney Disease
Decreased kidney function causes accumulation of waste products (urea, toxins) Leads to metabolic acidosis, hyperkalemia Electrolyte imbalance causes heart disease and fluid overload
41
pneumonia
Fluid build up in alveoli impairs gas exchange.
42
sildenafil
flushing vision GI muscle aches priapism (lasts > 4h) congestion *never use w/ NTG
43
Erectile dysfunction
trapped blood in penis
44
Asthma & sx
airway inflammation, bronchoconstriction, and mucus Triggers: Allergens, infections, exercise, cold air, irritants Wheezing, SOB, cough, tight chest, nocturnal
45
cystic fibrosis & sx
genetic disorder affecting lungs and GI mutations in a gene that controls mvmnt of salt and water in / out of cells. cause buildup of thick, sticky mucus. Persistent cough, freq lung infections, wheezing, poor wt gain, salty skin, GI issues.
46
Colchicine
treat and prevent gout attacks GI, Bone marrow suppression, muscle dmg, kidney or liver issues very precise dosing—too much is toxic avoid grapefruit, statins, NSAID, azoles, macrolides