Final Exam

Question 1

Acetazolamide

Answer 1

carbonic anhydrase inhibitor that promotes EXCRETION of bicarbonate (HCO3-)

used for acid-base balances i.e. high altitude climbing

Question 2

Furosemide/bumetanide/Enthacrynic acid

Answer 2

Brand name Lasix

acts on the ascending limb of the Loop of Henle
- regulates ability of water and sodium exchange by blocking specific cotransporter — ALTERING ability of fluid reabsorption

used to decrease Blood Pressure (indirectly)

Question 3

Amiloride and chlorothiazide

Answer 3

both act on distal tubule

amiloride promotes removal of fluid w/o removing K+ (by blocking Na channel) – important for people that need K+ retention

Question 4

p-aminohippurate (PAH)

Answer 4

solute that is completely removed by the kidney if infused into the blood

Question 5

thiazide

Answer 5

diuretic that inhibits Na/Cl cotransporter in early distal tubule (furosemide can not bind here even though there is a Cl receptor site — the shape is the main cause)