Final Exam Flashcards
History of Cocaine: Who First used it
Andean regions of Bolivia, Ecuador, northern Argentina, and Peru.
Spanish Attitude towards cocaine
–The religious use of the drug was inconsistent with Catholicism.
–The Spanish ultimately controlled the Incas’ access to the coca leaf.
•It became a form of payment.
How did cocaine get to Europe
European naturalists began to explore Peru and experiment with coca
Freud and cocaine
–He believed he had come upon a miracle drug.
–He advocated cocaine as a local anesthetic and as a treatment for depression, asthma, and other problems.
–He also thought cocaine was an aphrodisiac.
Medical uses for cocaine now
•Cocaine was prescribed by physicians as a topical medication.
•It became an application for eye surgery and
dental work.
Coca cola
Dr. John Stith Pemberton
•He invented Coca-Cola.
–It was advertised as containing the “tonic and nerve stimulant properties of the coca plant.”
Mariani
French chemist
•He used an extract from coca leaves in various patented products to cure common ailments.
-His most famous marketing of cocaine was sold as a popular wine: Mariani’s Coca Wine
History of cocaine restriction in Canada
- Opium and Other Drugs Act in Canada; 1911
- Opium and Narcotic Drug Act; 1929
- The main drug policy for the next 40 years
Attitude towards cocaine in 70’s
- Cocaine began to re-emerge in the 1970’s but it was fairly difficult to obtain and it was expensive
- Earned a reputation as the “champagne” of stimulants
Legal status of cocaine today
-Today Cocaine is a Schedule I drug under the Controlled Drugs and Substances Act
Crack - how it’s made
•A freebase cocaine produced by mixing cocaine salt with baking soda and water.
–The solution is heated, resulting in brittle sheets of cocaine that are “cracked” into smokable chunks or “rocks.”
History of amphetamines
-Use of cocaine in Canada declined during the years after the Opium and Other Drugs Act was enacted but new stimulants soon entered the scene: The Amphetamines (ATSs)
• -ATSs are a class of drugs first synthesized in the late 19th century that include: amphetamine, dextroamphetamine, and methamphetamine.
• -The first medical applications were developed in the 1920s and were patented in 1932.
Effects of long term use of stimulants
Stimulant Psychosis
-Paranoid delusions and disorientation resembling the symptoms of paranoid schizophrenia.
What are stimulant drugs used for medically today
-Treatment of ADHD (Ritalin)
Why meth production is problematic
- The chemicals used to produce meth are highly flammable
- The process requires the ingredients to be heated.
- A significant risk of explosion and fire exists.
Effects of Stimulants
- heart rate is up
- blood pressure is up
- respiratory rate is up
- and sweating increases
- blood flow decreases to the internal organs and extremities but increases to the large muscle groups and the brain
- body temperature is elevated and pupils dilated
- appetite suppressant
Stimulant withdrawl
-The primary symptoms are depression, anxiety, changes in appetite, sleeping disturbances, and craving for the drug.
Cannabis and what it’s used for medically
- Used in the Middle Stone Age
- 2800 BCE earliest known
- Used for sedation, treating pain and illness, countering the influences of evil spirits
How long cannabis was used in western countries
- 19th century
- 1840-1900 used medically in North America
what hemp is used for
- Staple crop
- Government’s first subsidized agricultural crop (abandoned for cotton)
why medical use of cannabis declined
- Inconsistent potency levels
- Increased use of opiates
- Development of other drugs (Aspirin)
growth of recreational cannabis use
- Began to grow in the 1920s along with public concern
- Canada did not use recreationally until mid 20th century
Country with highest usage rate of cannabis use
-2007 Canada (4x higher than the global rate of use)
what a vapourizer is and how it works
- Most efficient and healthy way of gaining the most levels of THC
- Marijuana is heated, hot vapor rises (THC), vapor is inhaled
Where does cannabis act in the body
-Psychotropic Effects (brain)
How THC is stored
- THC is carried through the bloodstream and deposited through the organs
- THC is the metabolized to less active products over time (Happens primarily in the liver)
- Metabolites are slowly excreted through the feces and urine
Physiological effects of cannabis
Acute Effects
- Bloodshot eyes, dilation of pupil, increase in heart rate, decrease in motor activity
Behavioural Effects
- Generalized decrease in psychomotor activity (dose-related), relaxation, excitement and restlessness
Cognitive Effects
- Impaired short-term memory, perception that time is passing by slowly
Emotional Effects
- Positive emotional changes (happy, excited, carefree), Some negative feelings (anxiety increased)
Social and Environmental Effects
- The role of marijuana in enhancing interpersonal skills
- The effects of cannabis on aggression and violence
- The role of marijuana in “amotivational syndrome”