Final Exam Flashcards

1
Q

Conformer (Exam 1)

A

an animal whose internal conditions match the external environment

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2
Q

Homeostasis (Exam 1)

A

Regulation of the internal environment to maintain stability

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3
Q

Hormone (Exam 1)

A

are secreted by the endocrine system. They are involved in regulating stress, metabolism, growth, reproduction, etc.

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4
Q

Negative Feedback (Exam 1)

A

The regulatory process that helps maintain the levels of some product by functioning to cycle back and essentially shut down a stimulus upstream.

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5
Q

Acclimation/Acclimatization (Exam 1)

A

Types of phenotypic plasticity associated with the chronic physiological timescale. The only difference between them is that acclimation is phenotypic plasticity occurring in a more controlled/lab setting and acclimatization occurs in nature/wild settings

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6
Q

The term “______” refers to the physiological components of animals that enable them to perform as they do. (Exam 1)

A

mechanism

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7
Q

Assuming the relationship depicted above is isometric, you can likely infer that the type of units being compared are the following (Hint: think about the dimensions being compared) (Exam 1)

A

y=mass
x length

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8
Q

Given the graph above, what feature would indicate a positively allometric relationship? (Exam 1)

A

b>2.98

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9
Q

A change in a synapse that would be categorized as synaptic plasticity includes: ______ (Exam 1)

A

long-term potentiation

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10
Q

Sweating in response to heat is an example of a(n) (Exam 1)

A

acute change

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11
Q

The electrochemical ion gradient, differential permeability to different ions, and the operation of sodium-potassium ATPase pumps together determine… (Exam 1)

A

the resting membrane potential

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12
Q

______ channels are responsible for the brief period of hyperpolarization at the end of an action potential (Exam 1)

A

voltage-gated potassium

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13
Q

The iodothyronines include hormones such as (Exam 1)

A

thyroxine

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14
Q

In a chemical synapse, the main component responsible for transmission of an impulse from presynaptic to postsynaptic cell is _____ (Exam 1)

A

any generic excitatory neurotransmitter

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15
Q

Which of the following could NOT be the postsynaptic membrane mechanism during an inhibitory postsynaptic potential? (Exam 1)

A

Increase in the permeability to Na+

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16
Q

In a neuromuscular junction, which ion enters the axon terminal in response to a presynaptic action potential? (Exam 1)

A

Ca2+

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17
Q

The glial cells forming myelin sheaths in the CNS are ________ (Exam 1)

A

Oligodendrocytes

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18
Q

Receptors for steroid hormones are typically found _______ because these hormones are _______ (Exam 1)

A

inside cells; lipid soluble

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19
Q

The time period during which a second action potential cannot be generated at a location on a cell membrane is referred to as the… (Exam 1)

A

absolute refractory period

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20
Q

Inhibitory post-synaptic potentials can be caused by the influx of which ion? (Exam 1)

A

chloride

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21
Q

Physiology is an integrative discipline. What does this mean? Explain how a physiologist must be an integrative biologist. What are the important considerations one must make when attempting a study of animal physiology? Pose a potential research question aimed at understanding animal physiology and explain how and which different biological subdisciplines would be used to answer the question. (Exam 1)

A

It means that not only does physiology integrate multiple disciplines (Bio, Chem, Physics, Ecology, Evolution), but it also integrated all levels of biological organization. When studying animal physiology it is important to acknowledge the levels of organizations you are interested in as well as the other scientific disciplines that will aid in answering the proposed question.
Q: How do different habitat types impact metabolic function?
For this question, it may be important to understand biology and chemistry as they work hand in hand to accomplish metabolic functions.

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22
Q

Synaptic plasticity is involved in the development of long-term memory and learning. Describe what we mean when we say synaptic plasticity, explain with examples the different ways that synaptic plasticity occurs, and describe two mechanisms through which synaptic plasticity operates. (Exam 1)

A

Synaptic plasticity describes when synaptic properties change with time and activity.

In sea slugs forms of learning, like habituation and sensitization were explored, showing real-life examples of synaptic plasticity.

Two mechanisms in which synaptic plasticity operates:
Presynaptically: changes in the rate of NT synthesis, storage, and release
Postsynaptically: sensitivity to NT can be increased or decreased under different circumstances

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23
Q

Physiological changes to the external environment occur over varying timescales. Compare and contrast each. Provide an example that demonstrates changes across different time frames. (Exam 1)

A

Acute: Immediate response (smallest scale)
Ex: sweating in response to heat

Chronic: Physiological changes occur after a longer time period (days, weeks, seasons); acclimation/acclimatization
Ex: an animal’s body insulation changes

Both chronic and acute are reversible and can affect individuals

Evolutionary: Associated with adaptations that come about usually via natural selection (largest scale). It is irreversible and rather than affecting individuals it affects populations over generations
Ex: Bird beak size

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24
Q

We know that temperature and body size influence virtually all physiological functions. Explain how scientists study physiological function as it relates to body size. Include in your answer a discussion of how they study allometry. (Exam 1)

A

Body size and scaling are considered when studying physiology because more often than not there is a (+) relationship between the two. Allometry allows us to view proportional relationships. If a relation is isometric then we know that growth is 1:1 and proportions are constant. This means during development dimensions will scale up and down with each other. in allometric growth, organism proportions change in with body size and depend on SA, V, and other physical parameters. The allometric equation (Y=aX^b) gives us insight into the scales exponent (b) when plotted and derived. This can give us insight into proportions and growth rates.
b>1 (not always 1): growth is (+) allometric (Y increases faster than X)
b< 1( not always 1): growth is (-) allometric (X increases faster than Y)
b=1 (not always 1): growth is isometric
Scaling is important when studying physiological function because it refers to the structural and functional consequences that come with changes in body size in otherwise similar organisms.

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25
Q

We know that unmyelinated axons conduct action potentials without decrement. However, some known diseases cause demyelination (the breakdown of myelin sheaths). When this happens, the conduction of action potentials is severely inhibited. Why do you think conduction is inhibited in these cases? Here I want you to speculate on the mechanism. Once you have identified the mechanism, speculate on the potential effects of such a demyelinating disease. (Exam 1)

A

The conductivity of APs is very dependent on myelination. Myelination is important in preventing ion leakage, insulation, and enhancing AP conductivity speed. The presence of myelin sheaths around axons also allows for saltatory conductivity, meaning the AP can jump from node to node. Myelin sheaths allow APs to travel further and faster. Without myelination, the conductivity of the AP is greatly diminished so APs may not be able to get to the next target. AP responses diminish with increased distance from the stimulation due to leaky channels. Leaky channels are not present in sheath areas so the AP occurs over longer distances. Conduction is inhibited in unmyelinated axons due to the presence of more leaky channels, counteracting the membrane potential. Diseases, like MS, in which myelination is diminished, will eventually cause neuronal function to diminish. This can cause physical movement ability to decrease, making a person wheelchair-bound. It will also cause NT signals to not be transmitted efficiently.

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26
Q

Osmoconformer (Exam 2)

A

an aquatic animal that allows its blood osmotic pressure to match and vary with the environmental osmotic pressure

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27
Q

Sarcomere (Exam 2)

A

are composed of contractile proteins (myosin & actin) which are responsible for muscle contraction. The arrangement of these proteins gives a striated appearance in skeletal muscle.

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28
Q

Cooperativity (Exam 2)

A

a behavior that occurs in protein molecules. The binding site of any one site to its ligand may facilitate or inhibit the binding of other sites on the same molecule to their ligands.

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29
Q

Sliding Filament Theory (Exam 2)

A

is the force of generation caused by the cross-bridges of thick filaments attaching to thin filaments & actively pulling them toward the center of the sarcomere.

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30
Q

Tidal Ventilation (Exam 2)

A

is when air from the environment flows into a passageway (ex. lungs) and mixes with stale air. Oxygen then diffuses into the blood.

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31
Q

In the body, water is found in the largest quantity in the… (Exam 2)

A

intracellular fluid

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32
Q

Which of the following scenarios will result in dissolved gas coming out of solution? (Exam 2)

A
  1. Collecting cold creek water, sealing the container, and allowing the solution to warm.
  2. Collecting cold creek water, adding salt, sealing the container, and allowing the solution to warm.
  3. Collecting cold creek water, adding salt, sealing the container, and keeping the solution at the original temperature
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33
Q

_____ is the law that relates partial pressure and concentration in aqueous solutions. (Exam 2)

A

Henry’s Law

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34
Q

Cutaneous water loss is primarily dependent on the permeability of the skin and _______ (Exam 2)

A

difference in vapor pressure inside and outside the body.

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35
Q

The blood of a freshwater teleost fish is ______ with respect to ambient conditions. (Exam 2)

A

hyperosmotic

36
Q

A vertebrate motor unit consists of… (Exam 2)

A

a single motor neuron and all of the muscle fibers that it innervates.

37
Q

The diagram is referring to what physiological process? (Exam 2)

A

Cross-current gas exchange

38
Q

At letter A in the diagram, O2 partial pressures are ______ the corresponding medium values and _____ from left to right (Exam 2)

A

lower than; decrease

39
Q

Which of the following animals is likely to have the highest O2 and CO2 exchange percentage via the skin? (Exam 2)

A

Lungless Salamander

40
Q

Which of the following denotes the correct sequence of blood movement through the human heart? (Exam 2)

A

Systemic vein —> right atrium —> right ventricle —> pulmonary artery —> pulmonary vein —> left atrium —> left ventricle —> aorta

41
Q

A muscle can produce maximal tension when it… (Exam 2)

A

starts from resting (intermediate) length

42
Q

Variation among species in the height of an oxygen equilibrium curve generally is a consequence of ________ (Exam 2)

A

differences in the quantity of respiratory pigment per unit blood volume.

43
Q

Diffusion of gases is dependent on ____ (Exam 2)

A

the difference in gas partial pressure

44
Q

The O2 partial pressure at which the blood is 50% saturated with O2 is known as the ______ (Exam 2)

A

O2 affinity

45
Q

Myoglobin has a higher oxygen affinity than hemoglobin. True or False (Exam 2)

A

True

46
Q

Relative to body size, respiratory surface area is greatest in… (Exam 2)

A

endotherms

47
Q

_______________ is the achievement of maximal muscle tension without muscle shortening (Exam 2)

A

Isometric contraction

48
Q

An ionic U/P ratio that is greater than 1 indicates that the urine contains _____ sodium compared to the plasma. (Exam 2)

A

more

49
Q

The surface area of the gas exchange membrane in birds is ______ than in amphibians (Exam 2)

A

larger

50
Q

Which biochemical mechanisms provide the majority of the ATP for short duration, powerful activities? (Exam 2)

A

Glycolysis and phosphogen

51
Q

Gases are exchanged in the fish gill via a process called _________ (Exam 2)

A

counter-current

52
Q

The shape of O2 equilibrium curves among species are different because ________________ (Exam 2)

A

of different protein globins present

53
Q

Briefly explain the Bohr Effect and its significance. (Exam 2)

A

The Bohr Effect describes the relationship between pH & oxygen affinity & temperature & oxygen affinity. As pH increases, oxygen affinity increases. As pH decreases, oxygen affinity decreases. As temperature increases, oxygen affinity decreases & vice versa. When there is a high P50 you have low oxygen affinity & vice versa. P50 is the point where 50% of oxygen is saturated. The Bohr Effect is a right shift in the curve. It’s significant when thinking about oxygen being picked up and released so it can be used for exercise & distribution through tissues.

54
Q

In a series of short statements, describe the excitation-contraction coupling process. (Exam 2)

A

An action potential causes Ach to enter the synaptic cleft from the presynaptic neuron and bind to a ligand-gated channel on the muscle. The channel opens & Na+ flows in the cell. This causes depolarization of the T tubules & the DHPR. The DHPR has a conformational change & the RyR Ca2+ channel opens, Ca2+ flows out & binds to troponin which causes tropomyosin to move & expose the myosin binding site & then myosin binds & starts contracting the muscle. Ach then needs to leave the synapse so AchE hydrolyzes it & choline is brought back into the cell to be used again.

55
Q

Compare & contrast co-current & counter-current gas exchange. Include in your answer a discussion of changes in O2 partial pressure in the blood & external medium.

A

Counter-current exchange is where media (air) & blood flow in the opposite direction. The air has a greater O2 partial pressure than the blood & oxygen flows from high to low PO2. The flow in opposite direction “allows oxygen to be distributed more evenly throughout the blood”. Counter-current is more efficient than co-current exchange
Co-current exchange is where blood & media (air) flow in the same direction which then makes it to where they reach equilibrium. Both exchanges are unidirectional & both exchanges work well for the organisms that have them

56
Q

Compare & contrast osmoregulation in freshwater & marine teleost fish. (Exam 2)

A

Freshwater teleost fish are hyperosmotic. They have active uptake of salt through their gills. They lose salt by diffusion through their gills.
Marine teleost fish are hyposmotic. They have an active loss of salt through their gills. They gain salt by diffusion through their gills.
Both secrete salt through their feces & intake salt from food.

57
Q

Briefly explain adaptations & physiological changes that take place during extended dives in diving mammals. (Exam 2)

A

The first adaptation is the collapse of the lung (thorax is highly compressible). If the lung wasn’t compressible, the mammal wouldn’t be able to dive because of buoyancy. The second adaptation or physiological change is bradycardia which is a decline in heart rate. The third adaptation is peripheral vasoconstriction which only allows blood flow to vital organs like the brain, lungs, and heart.

58
Q

2nd law of thermodynamics (Exam 3)

A

if an isolated system undergoes an internal change, the direction of that change always goes towards disorder.

59
Q

Thermal performance breadth (Exam 3)

A

the range at which organisms perform well as temperature as temperature increases. The range is in between CTmin & CTmax

60
Q

Indirect calorimetry (Exam 3)

A

is a measurement of metabolic rates by quantifying respiratory gas exchange or some other property besides heat and external work.

61
Q

Aerobic scope (Exam 3)

A

is the difference between maximal metabolic rate & basal metabolic rate

62
Q

Maximal aerobic speed (Exam 3)

A

is the speed at which VO2 (max) is reached. An organism can go the greatest possible distance with the least amount of energy used

63
Q

In mammals, the length of the loop of henle in nephrons is correlated with the… (Exam 3)

A

thickness of the renal medulla

64
Q

In mammals, the nonurea solutes are trapped in the collecting duct because the… (Exam 3)

A

collecting duct is impermeable to nonurea solutes but permeable to water.

65
Q

In mammals, the medullary interstitial fluid is _____ to the fluid in the collecting duct (Exam 3)

A

hyperosmotic

66
Q

During active transport NaCl in the ascending limb of the loop of Henle, the concentration of NaCl in inside the tubule… (Exam 3)

A

decreases

67
Q

Animals need energy to… (Exam 3)

A

create & maintain internal organization
maintain ion gradients
pump blood

68
Q

Suppose an animal is oxidizing food according to the following reaction: C16H32O2 + 23 O2 –> 16 CO2 + 6 H2) + 10,042 kJ/mol. what’s the respiratory quotient? (Exam 3)

A

16/23

69
Q

Which of the following is a factor that exerts a particularly large effect on metabolic rates?

A

Environmental temperature

70
Q

A measure of thermal tolerance. The body temperature where animals can no longer remove themselves from stressful conditions

A

CTmax

71
Q

Mechanism of heat exchange via contact with a surface.

A

Conduction

72
Q

An increase in endurance can be attained via conditioning. A primary mechanism facilitating this increase is

A

a change in aerobic enzyme production

73
Q

Mechanism of heat exchange associated with movement of the external medium

A

convection

74
Q

mass-specific metabolic rate is expected to be greatest in

A

birds

75
Q

if the basal metabolic rate was proportional to the mass of metabolically important organs (e.g. liver) then the scaling exponent would equal

A

1

76
Q

the primary site of filtration in the nephron is in the

A

glomerulus

77
Q

____ _____ is the temperature at which performance is maximized

A

thermal optimum

78
Q

for effective urine filtration, the blood pressure must _____ the sum of the colloid osmotic pressure and the capsular hydrostatic pressure

A

greater

79
Q

mass-specific metabolic rate _____ with increasing body weight

A

decreases

80
Q

The energy cost of moving a given distance that is independent of time and speed is called _________________.

A

net cost of transport

81
Q

The minimal cost of transport in swimming and flying organisms is attained at _______ speeds

A

intermediate

82
Q

increased metabolic rate due to activation of digestive processes is known as _________________.

A

system dynamic action

83
Q

Draw the relationship between metabolic rate and speed during terrestrial locomotion (left graph). Draw and explain how total cost of transport varies with locomotor speed and indicate the speed at which locomotion is most economical (right graph) LABEL AXES

A

TCOT decreases exponentially as locomotor speed increases. The speed at which locomotion is most economical is at maximal aerobic speed

84
Q

Explain a mechanism resulting in extreme freeze tolerance in some amphibians

A

Low molecular weight carbohydrates (glucose and glycerol) serve anti-freeze and cryoprotectant functions. They will mobilize glucose and show a pattern of enzyme activation during freezing

85
Q

describe the difference in the relative medullary thickness of mammals inhabiting arid, mesic, and aquatic habitats. Include in your answer an explanation of why this difference exists

A

Mammals inhabiting aquatic habitats don’t have a very thick medullary. This is because they live in water so they don’t have to worry about dehydration. Mammals inhabiting arid habitats will have a thicker medullary because they live in hot, dry environments so they have a thicker medullary to be able to hold onto water inside. Mammals inhabiting mesic habitats will have an intermediately thick medullary because they live in “tropical” environments so their medullary doesn’t need to be too thick or thin

86
Q

Using the graph below, explain how the thermal sensitivity of O2 consumption responds to temperature in two different time frames.

A

For the chronic response, 16 acclimated lizards had a higher metabolic rate than the 33 lizards. This is indicated by the increase in O2 consumption at each point on the 16 acclimated line. The acclimation increased the thermal sensitivity of O2 consumption for the 16 acclimated lizards.
For the acute response the 16 acclimated lizard had a higher metabolic rate than the 33 acclimated lizards.

87
Q

Explain why indirect calorimetry does not always provide a perfect measurement of metabolic rate.

A

There is a fixed O2:CO2 ratio when carbohydrates are being catabolized. The problem is, organisms don’t just consume carbohydrates so the ratio calculations would be inaccurate. We can figure out what foods are being metabolized by using the RQ