Final Exam Flashcards

1
Q

Toxic Vs. Hazardous

A

Hazardous refers to a dangerous physical or chemical agent. toxic refers to a substance with the potential to have adverse effects at certain concentrations.

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2
Q

Define “toxin”

A

Poison produced by living things

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3
Q

Define “Toxicant”

A

poison manufactured by humans or released by human activities

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4
Q

Define “Xenobiotic”

A

Substances “strange to” the organism

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5
Q

Define “toxicity”

A

Property of being poisonous

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6
Q

Define “Xenoestrogen”

A

A substance that imitates estrogen

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7
Q

Irritants

A

Corrosives, caustics, and other substances that damage tissue on contact

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8
Q

Asphyxiants

A

Any substance, especially a gas, that restricts or causes a reduced intake of oxygen into the body, leading to unconsciousness or death

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9
Q

Canarys in the coal mine

A

they were used to indicate when gas levels elevated to warn the miners to get out

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10
Q

Neurotoxin

A

Something that specifically attacks nerve cells

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11
Q

Respiratory fibrotic agent

A

cause formation of scar tissue o lungs which leads to reduced respiratory capacity

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12
Q

Allergens

A

Activate immune system response directly as antigens or indirectly by turning other substances into antigens

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13
Q

Endocrine Disruptors

A

Substances that interfere with or mimic the normal action of hormones (Example: BisPhenol A)

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14
Q

Carcinogens

A

Cancer causing agents

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15
Q

Teratogens

A

Results in birth defects by altering normal cellular differentiation or growth processes

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16
Q

Mutagens

A

Change the structure of genetic material

17
Q

Major routes of exposure of toxicants

A

-inhalation
-skin contact/dermal absorption
-ingestion

18
Q

Environmental factors affecting toxicity

A

1)Extrinsic
2)Intrinsic

19
Q

Extrinsic factors affecting toxicity

A

1)Biotic: factors resulting from the activities of a living things or any living component in an environment
2)Abiotic: non-living factors that effect the living organism community, air, water, soil, temperature, and climate

20
Q

Intrinsic factors affecting toxicity

A

1) Effects of previous exposure to toxicants
2)genetics
3)sex, age, life stage, activity level
4)nutritional status
5)disease status
6)stress

21
Q

what are the four steps to toxicity?

A

1)delivery
2)reaction
3)cellular dysfunction and resultant toxicity
4)repair and adaptation

22
Q

Modes of cellular dysfunction

A

Chemicals that causes DNA adducts, protein adducts, oxidative stress, and chemicals that specifically interact with protein targets

23
Q

Red tide

A

common name used for a harmful algal bloom. High concentrations of karenia brevis, a microscopic marine algae. can cause death in aquatic life and respiratory issues in humans

24
Q

Types of mutations

A

1)point mutation
2)chromosomal mutations
3)Genomic Mutations

25
Q

How are mutagens detected?

A

1)Human exposures using historical data
2)animal tests
3)bacterial tests