Final Exam

Question 1

What is the number of mEq of Na+ in 2g of Ampicillin sodium (MW = 371 C16H18N3NaO4S)? HINT: Valence is 1.

Answer 1

5.4

Question 2

Amphojel, a commonly used antacid product, contains 320 mg of Al(OH)3 per 5 mL. What is the number of Al3+ ion contained in a 2 Tbsp dose of Amphojel? (MW of Al(OH)3 = 78)

Answer 2

73.8

Question 3

How many mEq of Chloride are in a 30 mL dose of 10% KCl solution? (MW of KCl = 74.5)

Answer 3

40

Question 4

Calcium gluconate (MW of C12H22CaO14= 430) is available in a 10 mL vial containing 0.465 mEq of calcium gluconate in each mL of solution. How many grams of calcium gluconate are in the vial? HINT: Valence of Calcium =2

Answer 4

1

Question 5

How many milliOsmoles of mannitol (FW of C6H14O6 = 182) are contained in 1000mL of 25% mannitol solution?

Answer 5

1372

Question 6

How many milliOsmoles are found in 250 mL of 2% Sodium chloride solution assuming complete dissociation

Answer 6

171

Question 7

How many grams of dextrose are required to render the solution isotonic? (E of Dextrose=0.18)
Rx: procaine HCl (E: 0.21) 1.5%
Chlorobutanol (E: 0.24) 0.5%
Purified water q.s. 60 mL

Answer 7

1.55

Question 8

How many milligram of sodium chloride will be required for the following prescription to make an isotonic solution?
Rx: ‘Something?’ HBr (MW = 356, I = 1.8)
0.9% NaCl
Make isotonic solution. Dispense 30 mL

Answer 8

219

Question 9

Papavarine hydrochloride (MW = 376) is a 2-ion electrolyte dissociating in a given concentration. Calculate its sodium chloride equivalent.

Answer 9

0.16

Question 10

**Determine the maintenance dose of tobramycin for a 72 year old female patient weighting 187 lb and measuring 5 feet 3 inches in height with a serum creatinine of 2.8 mg/dL. The maintenance dose is 1.66mg/kg of ideal body weight every 8 hours. ****

Answer 10

21.2

Question 11

You have a stock Dopamine IV bag containing 250 mg dopamine in 500 mL of D5W. Using an infusion set delivering 60 drops per mL, how many drops per minute should be administered to an 80 kg patient getting 5 mcg per kg per minute.

Answer 11

48

Question 12

how many grams of boric acid would be required for the following prescription?
Rx: Scopolamine HBr (E:0.12) 0.5%
Boric acid (E:0.52) q.s.
Make isotonic solution. Dispense 60 mL

Answer 12

0.969

Question 13

You are to mix 6% ointment and 10% ZnO ointment to make 7.5% ZnO ointment. How many grams of 10% ZnO ointment are required to prepare 4 oz of 7.5% ointment?

Answer 13

42.5

Question 14

How many grams of 3% ZnO ointment can be made from 2 lb of 10% ZnO ointment?

Answer 14

3026

Question 15

From the following formula, calculate the amount of Salicyclic acid needed to prepare 8 oz of ointment?
Salicyclic acid 0.5 parts
Precipitated Sulfur 4.5 parts
Hydrophilic ointment 45 parts

Answer 15

2.27

Question 16

How many milliliters of an 0.9% solution of sodium chloride should be used in compounding the prescription?
Rx: Phenylaphrine HCl (E: 0.32) 1%
Chlorobutanol (E:0.24) 0.5%
Sodium chloride q.s.
Purified water ad 15 mL

Answer 16

7.67

Question 17

A proper dose of methylprednisolone for pediatric patients is 2mg per kg per day, divided into 4 doses given every 6 hours. How many milliliters of a 5mg/ml stock solution should be used for each dose for a 38lb patient?

Answer 17

1.7

Question 18

In preparing a certain ointment, a pharmacist used 28.35 grams of zinc oxide instead of the 31.1 grams called for. Calculate the percentage of the error on the basis of the desired quantity.

Answer 18

8.84%

Question 19

A prescription calls for 4mg of atropine on a balance where 180mg is the least weighable quantity with the prescription desired. Which of the following choices will provide the 4mg correctly, using lactose as the diluent?

Answer 19

weigh 180mg of drug, dilute with 8820mg of lactose, and weigh 200mg of mixture

Question 20

Amertan contains 5% tannic acid and 1:5000 of merthiolate in a water-soluble jelly base. How many milligrams of merthiolate would be contained in a 1 ounce(avoir) tube of Amertan?

Answer 20

5.67 mg

Question 21

Tylenol #3 contains 30mg of codeine and 325mg of acetaminophen per tablet. How many grains of codeine will be required to manufacture 24 bottles, each containing 60 tablets per bottle?

Answer 21

665 gr

Question 22

Acyclovir(Zovirax) suspension contains 200mg of acyclovir in each 5ml. How many grams of acyclovir are contained in a quart of suspension?

Answer 22

37.8 g

Question 23

If a pharmacist adds 4.5g of hydrocortisone powder to 60 grams of 2.5% (w/w) hydrocortisone cream, what is the resultant percentage strength of hydrocortisone in the product?

Answer 23

9.3%

Question 24

How many grams of tannic acid must be added to 320ml of glycerin having a specific gravity of 1.25 to make a 20% (w/w) solution?

Answer 24

100 g

Question 25

If 50ml of a 7.5% (w/w) sodium bicarbonate injection are added to 500 ml of a 5% dextrose injection, what is the percentage strength (w/v) of sodium bicarbonate in the product?

Answer 25

0.68%