Final Exam Flashcards
define compound
drug or combination of drugs prepared or compounded in a pharmacy according to a prescription
USP 795: three characteristic of compounding
DR-Patient-Pharm staff relationship
meds prepared are consistent w/ dispensing practices
limited to specific rx orders
NAPRA Standard: 1
Expertise in Drug Distribution System
NAPRA Standard: 2
Collaboration
NAPRA Standard: 3
Safety and Quality
NAPRA Standard: 4
Professionalism and Ethics
Define Pharmacy
a premise which prescriptions are compounded and dispensed for the public or sold
Define Pharmaceutical Care
provided drug therapy
Define Pharmacology
The study of the effects of drugs and the mechanisms of action on living things
Define Drug
agent intended for the use in the diagnosis/treatment of a disease
Define Pharmaceutical dosage form
type of preparation containing the drug which is administered accurately and safely by desired route
types of dosage forms
tablets/capsules
creams
suspensions
shampoos
sticks
lozenges
Define Pharmaceutical Ingredients
Active or medical ingredients
Define Route of admin
The route that the meds are given
Define dose
The amount of medication given at one time
When should you use a workplace label
When a potentially hazardous is transferred from a supplier container
Causes of sub-standard products
Lack of knowledge
Inadequate training
disregard for environment controls or procedures
calc errors
measuring errors
wrong ingredient
procedure errors
Type of water used for compounding
purified
Level A pharmacy
separate compounding area
Level B Pharmacy
dedicated room for compounding
Level C Pharmacy
Separate room with negative pressure
Simple compounding
Preparation that has a USP compounding monograph
Moderate compounding
Preparation that requires specialized calculations per individual
Complex Compounding
Preparation that requires special training and environment
Measuring volume usually refers to…
Liquids
What do you use to measure liquids
Graduated cylinders
Pipettes
Beakers
Measuring weight usually refers to…
solids or semi solids
you measure solids with…
Electronic scale, torsion balance
incorporation
mixing ingredients using mortar and pestle or ointment slab and spatula
Fusion
melting together ingredients with high melting points
Trituration
grinding a chemical into a fine powder using mortar and pestle
Levigation
reducing a chemicals particle size in a mortar or ointment pad using a liquid
Spatulation
mixing powders on an ointment slab using a spatula
Geometric dilution
Incorporation a small portion of the base into the powder
Eutectic Mixture
when two substances are mixed together they melt and solidify at a single temperature
Sizes of graduated cylinders
3 mL to 2L
Meniscus
the most curved top or bottom portion of the liquid, used to measure the amount of liquid
Largest dispensing bottle size
500mL
Largest Vial sizes
40 drams
Largest ointment pots/jars
500g
what kind of mixture is salt and ice
Eutectic
what kind of mixture is camphor and menthol
Eutectic
required temperature for a product that needs to be refrigerated
2c to 8c
describe a base
a substance when dissolved yields hydroxide ions
normal pH for blood
7.4
describe an acid
a substance wehn dissolved in water yields hydrogen ions
describe a paste
semi solid for topical application that has aqueous gels and fatty pastes
centipoise(cP) is used to measure what?
The viscosity of a liquid
describe a buffer
a compound that resists changes in pH of the solution
describe buffer capacity
measure of the resistance to change in the pH solution
Acidifying Agent
provides acid medium in liquid preparation for product stability
Alkalinizing agent
provides basic medium in a liquid preparation for product stability
Chelating agent
inactivates the catalytic activity of metal ions
Surfactants
lower surface tension between 2 liquids
Emulsifying agent
integrates two fluids that don’t generally mix
Viscostiy
the resistance to flow
name 2 viscosity increasing agents
cellulose derivatives
natural polymers
Name 2 synthetic polymers
carbomer NF
Poloxamer NF
encapsulating agents
thin shells that encase drug mixtures
Coating agents provide…
Protection, timed release
Disintegrates promote…
the break up of tablets into smaller pieces
Anti-adherants prevent…
The sticking of tablet powder or tablets to punches and dies
Binders cause…
Particles to stick together during granulation
Diluents provide…
bulk in tablets and capsules
Glidants improve…
Flow of powder in tabs and caps
Lubricants reduce…
Friction and adherence during tablet compression
Polishing agents make…
Tablets shiny
ointment base is…
semi solid dosage form
Cream base is…
Semi solid dosage form that has a fluid consistency
Gel base is…
Semi solid dosage form containing a gel agent that provides stiffness
Paste is…
Semi solid dosage form with aqueous gels and fatty pastes
Collodion is…
Semi solid dosage that is thicker
Humectant
Prevents water loss
Stiffening Agents
Increase thickness or hardness of product
Most common solvent
Water
7% alcohol acts as…
Preservative
what is considered an alcohol?
Ethanol
What is considered a ketone
Acetone
Methyl
Cyclodextrins
starch derivatives
Miscible
Two liquids that are soluble in each other
Solvent
A liquid that is capable of dissolving a substance
Spirit
Alcoholic Solution
Syrup
Oral solution that contain a high sugar level
Solution
clear liquid preparation where all ingredients are dissolved in a suitable vehicles
Lotion
Emulsion for external application to the skin
Solute
Substance that is dispersed in the solvent
Magma
Thick suspension of small inorganic solids
Most common emulsion
Oil in Water
Endodermic is…
Internal layer of skin
Elixir
Hydroalcoholic Liquid containing dissolved medicinal agents
Tincture
Contain vegetable/chemical substances in a alcoholic/hydroalcoholic solvents
Heating when preparing can…
increase the rate of solution for some substances
Stirring when preparing can…
increase the rate of dissolution
Suspension
Liquid that contains ingredients that are not soluble in the vehicle
Bottle method
Shake ingredients together in bottle
what does an emulsion require to breakup a liquid and increase surface area
Energy source
When a liquid is volatile use…
the bottle method
What is fusion
Heating slowly at low heat
Diadermic is…
going into and through the skin
Epidermic is…
External layer of the skin