Final Exam Flashcards

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1
Q

linear DNA

A

occurs in eukaryotes

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2
Q

circular dna

A

genetic material of prokaryotes, as well as mtDNA and cpDNA. does not have an end

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3
Q

prokaryotes vs eukaryotes

A

prokaryotes have no memebrane bound organelles and are usually unicellular

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4
Q

van der waals

A

relatively weak electric forces that attract neutral molecules to one another

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5
Q

nucleoside vs nucleotide

A

Nucleotides are simply a nucleoside with one or more phosphate groups attached

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6
Q

phosphate

A

A functional group characterized by a phosphorus atom bonded to four oxygen atoms

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7
Q

deoxyribose

A

pentose sugar with an aldehyde functional group in position 1. An aldehyde group consists of a carbon atom that is bonded to a hydrogen atom and double-bonded to an oxygen atom

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8
Q

ribose

A

Ribose is an aldopentose (a monosaccharide containing five carbon atoms) that, in its open chain form, has an aldehyde functional group at one end

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9
Q

chargaffs rule

A

there is always equality in quantity between the bases A and T and between the bases G and C.

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10
Q

chromatin, chromatids, chromosomes, and nucleosomes

A

Chromatin is a long chain of DNA. Chromosomes is rolled up DNA when it is going through cell division. Sister chromatids are the branches of the same chromosome. structure of a nucleosome consists of a segment of DNA wound around eight histone proteins

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11
Q

splicing

A

The process by which introns, the noncoding regions of genes, are excised out of the primary messenger RNA transcript, and the exons (i.e., coding regions) are joined together to generate mature messenger RNA.

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12
Q

start codon

A

ATG

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13
Q

stop codons

A

UAG, UAA, and UGA

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14
Q

exons

A

coding regions of dna

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15
Q

introns

A

non-coding regions of dna

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16
Q

point mutation

A

where one nucleotide is replaced with a different one

17
Q

transition

A

point mutation from purine to purine or pyrimidine to pyrimidine (A-G)

18
Q

transversion

A

point mutation between pyrimidine and purine (A-T)

19
Q

purine dna

A

A,G

20
Q

nonsense mutation

A

encodes stop codon prematurely

21
Q

missense mutation

A

causes change in amino acid. Conservative: properties of the amino acid remain the same

22
Q

hypomorphic

A

A type of mutation wherein the change in gene leads to the partial loss of the normal (wild-type) gene function

23
Q

hypermorphic

A

altered gene product possesses an increased level of activity, or in which the wild-type gene product is expressed at a increased level.

24
Q

heterologous

A

expression of a gene or part of a gene in a host organism which does not naturally have this gene or gene fragment.

25
Q

homologous

A

overexpression of a gene in a system from where it originates.

26
Q

BRCA1

A

tumor suppressor gene

27
Q

sickle cell amino acid changes

A

glu to val