Final Exam Flashcards
Pure Food and Drug Act
1906
Opium Exclusion Act
1909
Harrison Narcotic Act
1914
Prohibition of Alcohol
1920
Cannabis Statue Act
1937
Controlled Substance Act
1970
5 Schedules (I, II, III, IV, V)
Based on:
Potential for Abuse
Current accepted medical issues
Potential for physical and/or psychological dependence
Drug Dependence
When an individual becomes strongly attached to a drug
Dependency
Is subdivided into physiological and psychological
Physiological dependence
When there is a need by the body to have the drug present
The body accepts it into its makeup
A person experiences sickness if they stop taking the drug-withdrawal
Think caffeine, nicotine, codeine
Psychological Dependence
When a person develops an uncontrollable “craving” (mental or emotional) for a drug
May be more difficult to overcome
No sickness if they stop taking the drug
CRS
Colorado Revised Statuses
Schedule I
(worst)
High potential for abuse
No Current medical use in treatment in the USA
Lack accepted safety for use under medical supervision
LSD, MDMA, Psilocyn Mushrooms, Heroin, BZP
Schedule II
High Potential for use
Has current accepted medical use in treatment in the USA with severe restrictions
Abuse may lead to severe physical and/or psychological dependence
Morphine, Opium, Cocaine, Methamphetamine, PCP
Schedule III
Has potential for abuse less than those in sch. I and II
Has current medical use in the USA
Abuse may lead to low to moderate physical dependence or high psychological dependence
Amobarbital, Phenobarbital, anabolic steroids, ketamine
Schedule IV
Has low potential for abuse
Has current medical use in the USA
Abuse may cause limited (moderate) physical and/or psychological dependence
diazepam (valium) most benzondiazepines
Schedule V
Low potential for abuse
Current accepted medical use in the USA
Abuse may lead to limited physical and/or psychological dependency relative to substances in sch. IV
Various codeine solutions (not more than 200 mg/100 mL)
Penalties
2 classes of offenses
3 classes of misdemeanor offenses
6 classes of felonies
Drugs of Abuse
Stimulants Depressants/Hypnotics Hallucinogens Narcotics/Opioids Steroids
Stimulants
Amphetamine Methamphetamine Cocaine/Crack Benzylpiperazine Caffeine Ephedrine/pseudoephedrine
Stimulants
Amphetamine Methamphetamine Cocaine/Crack Benzylpiperazine Caffeine Ephedrine/pseudoephedrine
Amphetamine/Metamphetamine
created in 1887 trying to synthesize ephedrine to help with asthma
Effects of Amphetamine
Impaired speech, dizziness, insomnia, uncontrollable movements, psychotic episodes, impotence, dry, itch dry skill, increased aggressiveness, paranoia, headache, dry mouth, increased heart rate, increased breathing rate, increased blood pressure, rise in body temperature, fever and sweating
Cocaine
Schedule II
History: American Indians for thousands of years, Spanish conquerors, American companies 1890’s provided workers with cocaine for better production
Effect: Rush, Euphoria
Pharmacology: Cocaine is both a central nervous system stimulant and topical anesthetic
Class: CNS Stimulant
Cocaine
Varies with dose and tolerance of the user.
Increases alertness, wakefulness, elevates the mood, mild to high degree of euphoria, decreases fatigue, increases energy, insomnia restlessness
With high doses may exhibit a pattern of psychosis with confused and disorganized behavior, irritability, fear, paranoia, hallucinations, may become extremely antisocial and aggressive
BZP (benzylpiperazine)
Stimulant which gained popularity in the early 2000’s as a legal alternative to amphetamine, methamphetamine, and MDMA
Very similar to amphetamine and that clinicals would be ill-advised
200 BZP added to sch. 1
Stimulants with hallucinogenic properties
Depressants/ Hypnotics
Alcohol Barbiturates Benzodiazepines Opiates GHB/ GBL Rohypnol/Flunitrazepam Ketamine
Depressants/ Hynotics
There are numerous CNS depressants; most act on the brain by affecting the neurotransmitter gammaaminobutyric acid (GABA)
Neurotransmitters are brain chemicals that facilitate communication between brain cells
GABA
works by decreasing brain activity
Although the different classes of CNS depressants work in unique ways- it is through their ability to increase GABA activity that they produce a drowsy or calming effect