Final Deck #2

Question 1

When there is strong recognition of MHC in the thymus what happens to the maturing T cell?

Answer 1

Negative. Selection (apoptosis)

Question 2

What happens when a developing T cell has weak recognition of MHC and peptide in the thymus?

Answer 2

Positive selection (becomes single positive- either cd4+ or cd8+)

Question 3

What happens when a developing t cell in the thymus has no recognition of. MHC?

Answer 3

Apoptosis (death by neglect)

Question 4

What is the. Generative organ. For a. T cell?

Answer 4

Thymus

Question 5

Naive t cells are activated by what kind of cells before they begin proliferating

Answer 5

Dendritic cells

Question 6

Where. Does t cell activation by dendritic cell occur?

Answer 6

Lymph node

Question 7

Langerhans cells are immature DCs which do not express which receptor

Answer 7

B7

Question 8

Where does an Ag (carried by a DC) enter the lymph node

Answer 8

Afferent lymph vessel

Question 9

DC loaded with an Ag moves into the T cell zone which is located in which area of the lymph node?

Answer 9

Parafollicular cortex

Question 10

How do naive T cells enter the lymph node?

Answer 10

Blood stream