FINAL check Flashcards

1
Q

Classes of Contouring Tools

A
  • Manual
  • Image greyscale interrogation
  • Body atlas based methods
  • Statistical Shape modelling
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2
Q

ART Limitations

A

• Time and resource intensive process – financial burden
• More clinical outcome studies needed
• Appropriate patient selection
• What is the optimal number of replans? – Clinical benefit vs time and resources spent
• Consensus guidelines lacking
o Online vs Offline vs Hybrid
o Technical and QA considerations
• Patient-specific margins
• Plan of the day (multiply planning and staff training & education intensive)
• Extensive re-contouring required (more automation)

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3
Q

Speciality Image Sets

A
  • feature that combines 2 or more image sets to make a specialty image:

Maximum Intensity Projection
Minimum Intensity Projection
Average Intensity Projection

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4
Q

What is MIP?

A
  • maximum image projectory
  • displays the max no. of all pixels at the same locatin over the respiratory cycle
  • shows entire extent of tumour motion
  • caution for tumour close to diaphragm and chest wall
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5
Q

What is MinIP?

A
  • minimum image projectory
  • displays the min no. of all pixels at the same sptial location over the respiratory cycle
  • shows where some of the tumour always is
  • useful for liver tumours that present at low density
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6
Q

What is AvgIP?

A
  • average image projectory
  • displays the avg no. of all pixels at the same sptial location over the respiratory cycle
  • considered appropriate for planning which reduces the need for additional scan and thus dose
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7
Q

Define sterotactic

A
  • high precision image guided dose delivery (1mm, 1 degree)
  • highly conformal dose with steep dose drop off
  • intrafraction motion management
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8
Q

What is SBRT?

A
  • sterotactic body radiotherapy
  • dose escalation for targets close to OAR (extracranial e.g. spine, prostate)
  • 1 to 5 #
  • > 8Gy per fraction
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9
Q

What is SABR?

A
  • sterotactic ablative body radiotherapy
  • for ablation (extracranial e.g. liver, lung, renal)
  • 1 to 5 #
  • > 8Gy per fraction
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10
Q

What is SRS?

A
  • sterotacitc radiosurgery
  • historically intracranial but can be extracranial
  • single fraction
  • 12 to 90+ Gy per fraction
  • can use gamma, cyber or linac
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11
Q

What is SRT?

A
  • stereotactic radiotherapy
  • for large cranial lesions not suited for SRS (e.g. post operative cavities)
  • 2 to 5 #
  • lower BED then SRS
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12
Q

What does conventional dose fractionation allow?

A
  • normal cell repair
  • re-population after RT
  • re-distribution in cell cycle
  • re-oxygenation
  • radiosensitivity
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13
Q

What body areas move?

A
  • skeletal/muscle: stabilisation
  • respiratory (lungs, ribs, abdomen): 4DCT, breath hold or gating
  • cardiac: remains
  • peristalsis: compression
  • bladder and bowel: preparation or catherisation
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14
Q

Abscopal effect?

A

Localised irradiation perturbs the organism as a whole with consequences that can either be beneficial or detrimental

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15
Q

Motion Management strategies?

A
  • Breath hold – DIBH / EEBH (end expiratory breath hold)
  • Elekta BodyFix
  • Compression Belt
  • Compression Plate
  • Gating
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16
Q

Dose Response graph?

A

draw graph

17
Q

Rapidly proliferating cells, high a/b?

A
  • Not very sensitive to changes in fraction size or dose rate
  • True for most types of tumour
  • Evidence now that this is not true for prostate tumours
18
Q

Slowly proliferating cells, with low a/b?

A
  • Plenty of repair capability
  • Very sensitive to dose/fractionation
  • Late responding normal tissues are therefore sensitive to large dose / fraction
19
Q

Advantages of Brachy

A
  • Outpatient treatment
  • Dose optimisation - adaptive B/T planning
  • Reduced radiation exposure for staff under normal situations
  • More stable positioning
  • Smaller applicators
  • High dose rate = short treatment time
20
Q

Disadvantages of Brachy

A
  • More complex treatment and planning techniques
  • Compressed time frame for planning
  • Greater potential for error due to a much higher dose being delivered over a short timeframe
  • Potential for high radiation dose to staff and patient with source failure