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Semester 2 > Final > Flashcards

Final Flashcards

0
Q

What is the max O2 that 1g of Hb will bind?

A

1.36ml

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1
Q

At what value plasma ppO2 is Hb normally fully saturated?

A

10.6kPa

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2
Q

What are the usual PCO2 in arterial and mixed blood?

A

A - 5.3kPa, m- 6.1kPa

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3
Q

At what level is the sternal angle?

A

T4-5

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4
Q

At sea level what is the inspired PO2?

A

19.9 kPa

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5
Q

What inhibits endogenous overproduction of cortisol?

A

Metyrapone

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6
Q

In hypoxaemia, at what PaO2 do symptoms start?

A

<6.7kPa

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7
Q

Which two CD molecules on dendritic cells interact with Cd28 on Th cells?

A

80 and 86

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8
Q

What does lysozyme do?

A

Hydrolyses peptidoglycan from gram +ve walls

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9
Q

Which kinase is stimulated by insulin binding and causes vesicle translocation?

A

PKB

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10
Q

Which enzyme is diciest in Von Gierkes?

A

Glucose 6 Phosphatase

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11
Q

What do peroxisomes do?

A

Long chain FA -> shorter chain

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12
Q

Which transporters determine BBB permeability?

A

Monocarboxylic acid

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13
Q

Which enzyme is missing in MSUD?

A

a-ketoacid dehydrogenase

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14
Q

Which enzyme is missing in phenylketonuria?

A

Phenylalanine hydroxylase

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15
Q

Which enzyme is missing in alkaptonuria?

A

Homogentisate oxidase

16
Q

Which enzyme is missing in albinism.?

A

Tyrosinase

17
Q

Give 4 possible complications of sub endothelial MI

A

Ventricular rupture, papillary muscle rupture, chronic pump failure, arrhythmia

18
Q

Which prostaglandin type is prostacyclin?

A

PGI2

19
Q

What are the four lateral paired branches of the abdominal aorta?

A

Inferior phrenic,
Nal,
Suprarenal,
Gonadal

20
Q

What are the special lymphatic capillaries that carry fat from small intestine called?

A

Lacteals

21
Q

What type of epithelium is found in the bronchioles?

A

Ciliated simple columnar with goblet cells

22
Q

Approx how much O2 is bound to Hb in g/100ml?

A

16

23
Q

What embryonic structure becomes the diaphragm?

A

Septum transversum

24
Q

In which week does craniocaudal folding occur?

A

4th

25
Q

In which week does lateral folding occur?

A

3rd

26
Q

What do activated platelets release to promote more aggregation?

A

Thromboxane and ADP

27
Q

What is release from the liver when damaged and is therefore measured clinically?

A

Alanine transaminase ALT

28
Q

What is Conns syndrome?

A

Hyperaldosteronism

29
Q

What is the name of the lesion produced in TB?

A

Ghon focus

30
Q

What are examples of the four types of hypersensitivity reaction?

A

1- asthma
2- goodpastures
3- SLE GN
4- TB

31
Q

What does increased anion gap indicate?

A

Metabolic acidosis

32
Q

What causes diabetes insipidus?

A

Lack of ADH leading to dilute urine

33
Q

How is albumin moved through tubule epithelium?

A

Pinocytosis - endocytotic vesicles - digested - AAs released

34
Q

What are the three types of proteinuria

A

Glomerular, tubular and overflow

35
Q

What effect does prostaglandin E2 have on afferent arteriole?

A

Dilates

Semester 2 (6 decks)

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