Final Flashcards
What are 3 weight loss strategies? (Behaviours and attitudes)
1) cognitive skills — problem solving — replacing negative thoughts 2) personal attitude — understand personal relationship with food — sound emotional health 3) social support
What does reaching a plateau mean in terms of weight loss
It is the body readjusting to new weight, it is not failure
To keep the weight off, what must an overweight/obese individual do
Eat less and move more than someone else at that weight
True or false: it takes more effort to prevent weight regain than to prevent weight gain
TRUE
Capacity to make large scale changes to promote healthy behaviours is largely dependant on _______?
Political will
What three environments are more controversial national policies, give examples of each
— physical environment, e.g. protection of natural resources, and agricultural policies
— economic environment, e.g. social inequities and distribution of income
— consumer environment, e.g. protect consumers, and advertising restrictions
In terms of fat cell development, which is larger? Energy in or energy out
Energy in is greater than energy out
Where is energy stored in terms of fat cell development
In fat cells of adipose tissue
How is body fat reflected?
In the number of size and fat cells.
What happens when enlargement of the fat cells becomes to much for adipose tissue
Fat may accumulate in other areas of the body (e.g. visceral compartment)
What does an accumulation of the visceral compartment lead to
Metabolic disturbances such as insulin resistance and inflammation
What happens when energy out is greater than energy in in terms of fat cell development
— Fat cell size decreases; no change in number of fat cells
— ectopic fat likely decreased initially
During fat cell metabolism, what activity does LPL do?
— weight loss increases activity
— higher in obese people
— gender dependent
What is the relationship of fat oxidation and obese individuals
Fat oxidation is lower in obese individuals
Describe the set-point theory
- body likes to maintain homeostasis
- during weight gain, the body increases metabolism to burn excess calories
- during weight less, the body will store more fuel to prevent fat stores from decreasing
_______ may determine predisposition to obesity
Genetics
What can minimize the genetic influence on body weight
Physical activity
What is the obesity gene in adipose tissue
Leptin
What does leptin do
HORMONE
- maintains homeostasis
- suppresses appetite
- increases energy expenditure
- when obese people lose weight, their leptin levels drop, and they feel more hungry
What is leptin resistance
- levels increase with BMI
- fails to suppress appetite or enhance energy expenditure
- excessive fructose consumption introduces leptin resistance and accelerate fat storage
What is ghrelin
- a protein synthesized in the stomach
- acts as a hormone
- stimulates appetite
- increases after weight loss
What affect does lack of sleep have on ghrelin and leptin
Lack of sleep increases ghrelin and decreases leptin
What is peptide YY
- protein produced in the GI tract after a meal
- decreases appetite
- obese people have lower levels when fasting and have less released after a meal than non-obese
Describe physical inactivity
Requires little energy beyond RMR
Watching tv influences food choices and snacking
What are the physical activity recomendations to prevent weight gain, and for health canada
To prevent weight gain - 60 minutes per DAY
For health canada - 150 minutes per WEEK
What is food?
- essential for life
- symbol of culture
- ritual object
- product to be purchased
- can cause pleasure
- cause guilt and shame
What are some of the physiological influences of food
Sight, smell, sound, texture
What prompts us to eat
Hunger
What sends signals to eat or to feel full?
The hypothalamus
Humans are born with unlearned preferences for _____ taste and rejecting ____ and _____
Sweet, sour, bitter
What is anorexia of aging
Reduced smell and taste of food
Explain what is meant by “food preference and acceptance is a learned behaviour”
- finish your plate, meat and potatoes
- dessert with dinner
- positive and negative associations
Name two ways of social conditioning in terms of food
Food role models and peers
Food as a reward or punishment
- you can have dessert if you eat your broccoli
What are some non-nutritional elements of perceptions of healthy eating
Freshness
Organic
Unprocessed
Home-made
What is considered “environment”
All circumstances that we encourager daily
What are some social and cultural cues that may lead to weight gain
Birthday parties Holidays Sleepovers Movie theatres Baseball games
What is the most important barrier to healthy eating
Poverty
What is the poverty obesity paradox
- food insecurity leads to both under or over nutrition.
- because of this it is possible to be undernourished and obese
What is organized tricking
- food marketing
- advertising
What is the key to weight loss success
Motivation
When is weight loss recommended for overweight or obese individuals
- when a life threatening disease is present
- two or more risk factors for disease exist
Willpower is a _______ _________
Fixed commodity
What are some of the social consequences of obesity
- discrimination
- judgement
- laziness
What is the psychological problem circle for overweight individuals
I am fat and unhappy
I want to be happy
If i lose weight i will be happy
I try too hard to reach an unrealistic goal
I lose a little weight but then regain it
What are 3 aggressive treatment of obesity
- Drugs
- gastric bypass
- attaching jejunum to the stomach, by passing most of the stomach. Malabsorption and low failure rate. 30-60ml - gastric sleeve
- portion of stomach, top to bottom is removed. 100-150ml. Performed laparoscopically
What are the three things to do if you want to lose weight and keep it off
- Food record
- Walk 150 minutes every week
- Self weigh periodically
What are the guidelines for reasonable goals for weight loss
- small changes
- modest weight loss (5-10%) per 6 months
- incorporation of healthy eating ad physical activity into daily living
What are some weight loss strategies for eating plans
- realistic energy intake
- emphasize nutritional adequacy
- eat small portions
- water
What percent of the body is water
60%
In lean tissue, what fraction of weight is water
3/4
In fat tissue what fraction of weight is water
<1/4
What groups have the lowest proportion of water
Females, obese, elderly
What are the functions of water
- carries nutrients and waste products
- lubricant
- solvent
- hypothalamus
- structure
Water intake is controlled by _____
Hypothalamus
What are the symptoms of dehydration and water intoxication
Dehydration: thirst, weakness, exhaustion, delirium
Water intoxication: confusion, convulsions, death, hyonatremia
Name the sources of water from highest to lowest
Liquids
Foods
Metabolic water
Name the losses of water from highest to lowest
Kidneys
Skin
Lungs
GI tract
What fraction of water is inside and outside cells
Inside cells: 2/3
Outside cells: 1/3
What are the electrolytes inside the cell
Potassium phosphorus
What electrolytes are outside the cell
Na cl
What regulates fluid movement
Proteins
How to proteins regulate fluid movement
Attract water
Transport proteins: sodium potassium
Where does regulation of fluid and electrolyte balance occur
- GI tract
- kidneys
What are some causes of electrolyte imbalances
- prolonged vomiting or diarrhea
- heavy sweating
- burns/wounds
- medications
Fluids and electrolytes help maintain ____
PH
What is pH buffered by
Blood
Kidneys
Lungs
What are the roles of sodium in the body
- fluid balance
- acid-base balance
- nerve transmission
- muscle contraction
What are two food additives used to prolong shelf life
Salt and sugar
What can sodium cause if UL is crossed
High blood pressure
Hypertension
What diet is recommended for sodium control
DASH
What symptoms are due to sodium deficiency
Vomiting, heavy sweating, diarrhea, hyponatremia
- rare
Chloride is involved in ____________
Fluid and electrolyte balance
What is chloride associated with
Sodium outside the cell and potassium inside the cells
— moves passively through membrane channels
What is potassium
A cation found inside cells
What are the roles of potassium in the body
- fluid and electrolyte balance
- nerve transmission and muscle contraction
- steady heartbeat
- sodium and potassium trade places
What is the UL for potassium
There is no UL
What is the 2nd most abundant mineral in the body
Phosphorus
Where is the majority of phosphorus in the body
85% in the bones
What are the roles of phosphorus
- part of DNA or RNA
- lipid bilayer and lipoproteins
- ATP
- regulates enzymes
What are heat cramps
Subtle twitches to painful spasms
Excessive loss of water and sodium
Strenuous activity in hot environments
What is heat exhaustion
Result of exertional activities in a hot environment
Increased body heat, less water
What are the symptoms of heat illnesses
Headache Nausea Vertigo Weakness Rapid breathing Thirst Loss of consciousness
What is heat stroke
- serious
- sweating stops
- body temp increases
- hyperventilation, confusion, death
What is the term for water intoxication
Hyper hydration
Why is thirst a poor indication of hydration status
- some people don’t feel thirsty
- some people forget
What is the role of an antioxidant
To protect cells from oxidative damage
Vitamins eliminate what
Free radicals
Minerals act as ______ for enzymes
Cofactors
Antioxidants ______ free radicals
Neutralize free radicals
Where are Epithelial cells found inside and outside of the body
- outside (skin)
- inside (mucous membranes)
What is the job of vitamin A in the body
- promotes skin differentiation of epithelial and goblet cells
- protects skin from sun damage and integrity of mucous membranes
What is the job of vitamin A in preproduction and growth
- sperm development in men
- fetal development in women
- bone remodelling
- failure of growth in children
Describe vitamin A deficiency
- Can take 1-2 years
- night blindness
- lack of rhodopsin
- inability to recover from changes in light
- xerophthalmia (total blindness)
- drying and softening of cornea
- keratinization
What are the consequences of vitamin A toxicity
Birth defects
Bone defects
What happens during vitamin A toxicity
Binding proteins become swamped
Free vitamin A causes damage
What foods are high in vitamin A
Broccoli Carrots Tomatoes Milk Soy Egg Beef liver
What vitamin is the primary defender against free radicals
Vitamin E
What is the job of vitamin E in terms of antioxidants
Prevents free radicals from producing more free radicals
Which vitamin lowers the risk of CVD
Vitamin E: it oxidizes LDL
What happens in vitamin E deficiency
Fat malabsorption
Red blood cells break open
- erythrocyte hemolysis in premies
What is the primary source of vitamin E
Vegetable oils
What is the role of vitamin c as an antioxidant in the body
Gives up electron to stop free radical damage
Enhances iron absorption
When stressed, where is vitamin c secreted from
Adrenal glands
Excess vitamin C is secreted by the ___
Kidneys
Who needs more vitamin C
Smokers
What is the name of a vitamin C deficiency disease
Scurvy
What symptoms arise due to vitamin C deficiency
Inadequate collagen, wound healing ceases, teeth become loose, skin becomes dry, rough and scaly
What symptoms arise from vitamin C toxicity
GI disease, diarrhea, iron overload
What foods are high in vitamin C
Broccoli Tomato Blueberries Kiwi Citrus
Which vitamin is associated with heart disease and cancer?
Selenium
Which element is selenium similar to
Sulphur
Which vitamins work synergistically
Vitamin E and selenium
Vitamin E and A
Vitamin E and C
What are two lines of defence against free radicals
Antioxidant enzyme defence system
Antioxidant nutrients, including photochemicals
What disease is inversely related to vegetable intake
Cancer
Oxidation of LDL leads to
Atherosclerosis
The major role of vitamin A is
Vision
What are bones composed of
65% mineral crystals
35% organic substances
What are the two types of bone tissue and how much of each is the bone made up of
Cortical: dense, outer walls 80%
Trabecular: lacy, spongy 20%
What are the functions of bone health, structurally and metabolically
- physical support
- protection
- muscles attached to bones
- storage reservoir for minerals
What years does bone growth occur
Conception to 14 years for girls, 17 years for boys
As we age, what is greater, osteoclasts or osteoblasts
Osteoclasts > osteoblasts
What age is peak bone mass
From 14-30
Bone loss occurs from the ages?
30+
What is resorption
Surface of the bones are broken down
What are osteoclasts
Cells that erode the surface of bones
What are osteoblasts
From new bones
What is the most abundant mineral in the body
Calcium
Where is calcium found in the body
99% in bones, 1% in fluids
What is DEXA
Dual energy x ray absorptiometry
What happens when a high calcium level is achieved
- thyroid gland releases calcitonin
- calcitonin functions to
- prevent calcium reabsorption from kidneys.
- limit calcium absorption from intestines
- inhibit osteoclasts from breaking down bone
What happens to the body when low calcium level
- Parathyroid hormone is released
- PTH stimulates activation if vitamin D
- PTH and vitamin D cause
- kidneys to retain more calcium
- osteoclasts to break down bone and release calcium
- stimulation of calcium absorption from intestines
What is bioavailability
The degree to which a nutrient is absorbed and used
What percentages of calcium absorption are at each stage in life
Adults: 30%
Pregnancy: 50%
Children: 50-60%
What are some factors that enhance calcium absorption
Stomach acid and vitamin D
What are some factors that inhibit vitamin c absorption
Lack of enhancers High phosphorus Phytates Oxalates Fibre
Calcium deficiency leads to?
Low bone mineral density (BMD)
- peak BMD is at 20 years
Osteoporosis
- 1/4 women and 1/8 men over 50 years
True or false: blood calcium level directly reflects calcium status
FALSE: blood calcium level does not reflect calcium status
What foods are high in calcium
Milk
Cheese
Kefir
Tofu
True or false: green veggies and cauliflower absorb MORE calcium than milk and tofu
TRUE
What happens if you consume too much calcium
- excreted from the body
- supplementation can lead to mineral imbalances
What is hypercalemia
High blood calcium caused by cancer and overproduction of PTH
What is PTH
Parathyroid hormone
What is hypocalcemia
Low blood calcium, can be caused by kinder disease or overproduction of parathyroid hormone (PTH)
Which sex consumes less calcium daily
Females
Where is excess vitamin D stored
The liver and fat tissue
Is vitamin D fat soluble?
Yes
How is vitamin D synthesized
UV light from the sun
Why is vitamin D a hormone?
Is is synthesized in one location and acts in another location
What happens when blood calcium rises
- calcitonin inhibits the activation of vitamin D
- calcitonin prevents calcium reabsorption in the kidneys
- calcitonin limits the calcium absorption in the intestines
- calcitonin inhibits osteoclasts cells from breaking down bone preventing the release of calcium
What happens when blood calcium falls
- PTH stimulates the activation of vitamin D
- vitamin D and PTH stimulate calcium reabsorption in the kidneys
- vitamin D enhances calcium absorption in the intestines
- vitamin D and PTH stimulate osteoclasts cells to break down bone releasing calcium into the blood
Describe what happens when vitamin D is absorbed into the body
Skin: 7-dehydrocholesterol + UV light from the sun
Heat from the body: previtamin D —-> vitamin D3 (calciol)
In the liver: calcidiol
In the kidneys: calcitriol
what is the sun exposure recomendation
5-10 minutes 3x/week
- skin cancer risk increases
Who is usually insuffient with vitamin D
- dark skin
- breastfeeding
- fat malabsorption
What months can Canadians NOT rely on sun exposure for vitamin D
October - April