FINAL Flashcards

1
Q
Odontogenic Keratocyst (OKC) 
managmenet
A
  •   E&C with poten7al extrac7on
  •   If larger – consider staged marsupializa7on and E&C
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2
Q

pt presents with established MRONJ

A

Consult and Refer!!!

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3
Q

allograft and xenograft have what type of potential

A

Osteoconductive

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4
Q

Marsupializa*on •  Disadvantages

A

–  Cannot histologically examine the en7re cys7c wall
•  Areas leI behind may be more aggressive than
piece removed
–  Pa7ent inconvenience with home care

–  Occasional secondary infec7ons

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5
Q

correct vertical periodontal defects

A

orthodontic eruption

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6
Q

Residual cyst management

A

Residual
•  E&C

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7
Q

bone infection

A

osteomyelitis

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8
Q

removing a known aggressive cyst such
as an OKC (high recurrence) use what procedure

A

Enuclea*on & cure1age

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9
Q

3.  Lateral periodontal cyst
managment

A

• Enuclea7on with preserva7on of tooth

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10
Q

Treatment of choice for cystic lesions

A
  1. Enucleation
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11
Q

three phases during distraction osteogenesis

A

latency

distraction

consolidation

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12
Q

A condition in which Irradiated bone becomes
exposed through a wound in the overlying
skin and/or mucosa and persist without
healing for 3 to 6 months

A

osteo-radio-necrosis

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13
Q

Known as “ decompression” technique

A

Staged marsupializa*on & enuclea*on

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14
Q

how to examine functional load in TMJ area

A

bite tongue blade between most
posterior teeth bilaterally and incisors

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15
Q

taking PO oral bisphosphonates

A

Informed consent/Medical
consult if considering drug holiday!

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16
Q

  Asymptomatic patient receiving IV therapy
for bisphosphonates

A

§  Maintain oral hygiene §  Avoid osseous injury

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17
Q

treatment sequence for internal derangement of TMJ

A

arthrocentesis

arthroscopy

open surgery

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18
Q

Member of the cytokine family of growth factors

A

BMP (Bone Morphogenic Protein)

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19
Q

Enuclea*on •  Disadvantages

A

–  Possible pathological fracture
–  Devitaliza7on of teeth
–  Injury to nerve

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20
Q

minimum distance between implant incisive canal

A

avoid midline maxilla

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21
Q

indications for arthrocentesis

A

• Acute closed lock • Acute trauma (hemarthrosis) • Capsulitis/synovitis

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22
Q

clinical stage 3 MRONJ treatment

A

§  Surgical debridement or
resection §  Antibiotic therapy

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23
Q

A true cyst contains an

A

A true cyst contains an epithelial lining

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24
Q
A
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25
Q

what type of implants can be used to avoid the sinus

A

angled implants

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26
Q

surgically lengthen bone

A

distraction osteogenesis

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27
Q

New bone formation from differentiation of
osteoprogenitor cells, derived from mesenchymal
cells, into osteoblasts.

A

Osteoinduction

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28
Q

–  Any cyst that can be removed in en7rety & safely
without harming adjacent structures should use what procedure

A

  Indica7ons

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29
Q

Palpation – general principles
Light pressure over

A

Light pressure over lateral capsules: 5 lbs.

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30
Q

intraroral donor sites for block grafting

A

chin and ramus

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31
Q

two methods of horizontal augmentation

A

guided bone regeneration

block grafting

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32
Q

Tricks to detect guarding (excessive limitation
of ROM)
during TMJ exam

A

– Observe during interview, note interincisal ROM
– Look for tonsillar hypertrophy with tongue blade

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33
Q

performed through the implant osteotomy when you want to place an implant but need a few additional mm of bone

A

indirect sinus augmentation

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34
Q

increased risk of graft/membrane exposure

A

concern with vertical augmentation by grafting

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35
Q

vertical augmentation of the sinus predictable/non predictable

A

very predictable (posterior maxilla area)

everywhere else have to use distraction osteogeneiss or orthodontic eruption

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36
Q

Enucleation & Curettage of Jaw Tu m o r s
in what tumors specifically (4)

A

•  Odontoma

•  Ameloblas7c fibroma/
fibro-odontoma

  •   AOT
  •   Cementoblastoma
  •   Odontogenic fibrom
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37
Q

name a source of autograft that has no long term morbidity and has no issues on pt function right after

A

no long term morbidity, no issues walking right after, no gait disturbances, a little scar-anterior iliac crest

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38
Q

clinical stage 1 treatment

A

§  Oral antimicrobial rinses
(e.g. Peridex)

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39
Q

horizontal augmentation for small, well-defined, concave defects

A

guided bone regeneration

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40
Q

Staged marsupializa*on & enuclea*on •  Lesion marsupialized and allowed time for:

A

–  Bone cover of vital structures

–  Increased strengthening of jaw

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41
Q

– Best for internal derangement, effusion

A

MR

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42
Q

Preauricular tenderness may be either

A

joint or muscle
finding

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43
Q

Aggressive lesions either by
histopath or clinical behavior
tx

A

Resection of Jaw Tumor

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44
Q

diseases associated with bone healing problems

A

drug related osteonecrosis of the jaws

osteo-radio-necrosis

osteomyelitis

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45
Q

like a catch, but stays that way for
minutes, hours, days, etc.
in TMJ area

A

Limited/Impaired movement
– Closed lock

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46
Q

BMP-2=Infuse® Not approved in

A

Not approved in children/skeletally immature
patients

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47
Q

Marsupializa*on •  Indica7ons

A

–  Adjacent vital structures at risk with enuclea7on
–  Difficult surgical access to all por7ons of cyst
•  Increases recurrence rate

–  Medical compromise

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48
Q

Palpation – general principles
– Moderate pressure

A

Palpation – general principles
– Moderate pressure over masticatory muscles: 10 lbs.

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49
Q

controlled displacmeent of surgically created fractures

A

distraction osteogenesis

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50
Q

what happens during the latency stage of distraction osteogenesis

A

revasculariztion

osteoprogenitor cells accumulate

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51
Q

Does not actually produce bone – conducts bone
forming cells from host into/around the scaffolding.

A

Osteoconduction

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52
Q

full-thickness por7on removed resection technique

A

Segmental –

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53
Q

•  Most odontogenic
tumors tumors tx

A

Enucleation & Curettage of Jaw Tu m o r s

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54
Q

Local removal of the tumor by instrumenta7on
or direct contact with the lesion

A

Enucleation & Curettage Surgical Te c h n i q u e

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55
Q

Removal of the disk

A

Meniscectomy=Discectomy:

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56
Q

how long does the conslidation phase occur in distraction osteogenesis

A

2-3 months

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57
Q

Enuclea*on & cure1age •  Advantage

A

–  Destroys any suspected epithelial remnants,
decreasing chance of recurrence

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58
Q

Total Joint Replacement • Indications

A

• Severe degeneration, usually mostly of the condyle
• foreign body giant cell reaction
• rheumatoid arthritis
• Juvenile Idiopathic Arthritis
• Idiopathic condylar resorption • Recurrent fibrous or bony ankylosis • Failure of other reconstructive procedure, e.g.
costochondral graft

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59
Q

PHASE I
 Transplanted cellular bone in bone grafts produces new

A

Transplanted cellular bone produces new osteoid.

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60
Q

why does MRONJ happen in the jaws

A

¡  Increased bone turnover in the jaws
(Remodeling rate is 10 times more than long
bones )

¡  Thin overlying oral mucosa due to jaw
anatomy.

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61
Q

Removal of the en7re cys7c lesion without rupture

A

. Enuclea*on

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62
Q

requires a “good root” with a non-restorable crown

A

orthodontic eruption

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63
Q

minimum distance between implant and natural tooth

A

2mm

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64
Q

minimum distance between implant and mental nerve

A

5mm from anterior of bony foramen

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65
Q

Formation of new bone from either host-derived or
transplanted osteoprogenitor cells along a biologic
framework.

A

Osteoconduction

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66
Q

how to palpate the temporalis insertion

A

Palpate posterior maxillary vestibule
Posterior on ascending ramus

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67
Q

how long do you leave the cavity open with marsupialization

A

Un7l goals for choosing marsupializa7on have
been met

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68
Q

BMP (Bone Morphogenic Protein)
is higher in what type of bone

A

Higher in cortical bone vs. cancellous.

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69
Q

mechanical obsturction in TMJ area can mean

A

internal derangement

arthropathy

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70
Q

three things we are concerned about with jaw tumors

A

•  Lesion behavior •  Anatomic loca7on •  Desired reconstruc7on
results

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71
Q

indicated for inadequate vertical dimension

A

sinus augmentation

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72
Q

Cadaver bone

A

Allografts/Homografts

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73
Q

Special Challenges to Advanced Implant Placement

A

Immediate Placement

Posterior mandible

Atrophic maxilla

Pathology ablation

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74
Q

minimum distance between implant and infeirior bordre of md

A

1mm

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75
Q

• Muscle palpation
in TMJ area

A

– Work from top down, starting at temporalis crest
• Temporalis, masseter • Repeat for SCMs, posterior neck/trapezius

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76
Q

how long for bony fill in enucleation

A

6-12 months

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77
Q

Inspection
clinically in TMJ area

A

– Facial asymmetry
– Swelling
– Asymmetric facial movement
– Masticatory muscle hyperplasia, hyperactivity

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78
Q

Resection of Jaw Tumors
name specific tumors

A

•  Ameloblastoma •  Myxoma •  CEOT •  Squamous odontogenic tumor

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79
Q

only _____ grafts are capable of osteogenesis

A

Osteogenesis

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80
Q

Consider __________in highly sensitive patients in TMJ area

A

Consider neuropathic pain (e.g. tactile allodynia,
hyperalgesia) in highly sensitive patients

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81
Q

new bone forms in gap

A

distraction osteogenesis

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82
Q

name 3 oral bisphosphonatets

A

¡  Fosamax (alendronate)
¡  Actonel (risedronate)
¡  Boniva (inandronate)

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83
Q

Synthetic analogs of inorganic pyrophosphate

A

bisphosphoantes

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84
Q

put a suture in the tissue and leave it open to the oral cavity and let it burst on its on

A

Marsupializa*on

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85
Q

__________grafting for replacement of TMJ

A

Costochondral grafting for replacement of TMJ

86
Q

Localized involvement with involvement of cortical and medullary bone

treatment

A

stage 2 osteoradionecrosis

Conservative : Local debridement w,w/o HBO Chlorhexidine MW

87
Q

•  Cyst is enucleated first

•  Mechanical (burs) cure]age is performed to remove
1-2mm of bone at the en7re periphery of the bony
cavity

A
  1. Enuclea*on & Cure1age (E&C)
88
Q

soft tissue envelope expands

A

distraction osteogenesis

89
Q

Ectomesenchymal
tumors

A

1.  Odontogenic fibroma 2.  Odontogenic myxoma 3.  Cementoblastoma

90
Q

allows our bones to repair from daily micro-trauma

A

bone remodeling

91
Q

barrier isolates the defect from surrounding soft tissue

A

guided bone regeneration

92
Q

asymptomatic pt still taking oral BP <4 years + risk factor (sterior/angiogenic meds)

A

stop BP therapy 2 months prior to treatment

93
Q

clinical stage one MRONJ

A

§ Exposed/necrotic bone § Asymptomatic § No infectio

94
Q

TMJ/MPD pain may trigger

A

migraines

95
Q

Tumors that would be
difficult to remove in
en7rety by enuclea7on/
cure]age alone
tx

A

Resection of Jaw Tumors

96
Q

what is tyrosine

A

anti-angiogenic medications

97
Q

Initiates osteoinduction.

A

BMP (Bone Morphogenic Protein)

98
Q

pathogenesis of osteoradionecrosis

A

¡  Hypoxia ¡  Hypovascularity ¡  Hypocellularity

99
Q

minimum distance between implant and inferior alveolar canal

A

2mm from superior aspect of bony canal

100
Q

does vertical or horizontal have a greater resorption rate

A

vertical

101
Q

what muscles in the TMJ area are not are not directly palpable

A

Pterygoid muscles

102
Q

inter-implant distance

A

3mm between outer edge of implants

103
Q

Have osteoinductive and conductive properties.

A

Osteogenesis

104
Q

what is really important before doing an extraction

A

Ta ke thorough medical history before performing teeth extraction !!!

105
Q

Slow-growing, non-
aggressive tumors tx

A

Enucleation & Curettage of Jaw Tu m o r s

106
Q

Determines quality of bone

A

Two-Phase Theory of Osteogenesis
 PHASE II

107
Q

what radiographic findings are seen with osteomyelitis

A

moth eaten appearance

radio opacities -? sequestra

108
Q

Methods to restore lost tissue volume

A

Grafting

Distraction

Orthodontic Eruption

109
Q

Types of Bone Grafts

A

Autograft

  1. Allograft
  2. Xenograft
  3. Alloplast
  4. Recombinate graft
110
Q

Opening cyst to oral cavity

A

marsupializa7on

111
Q

Name Developmental Cysts Developmental

A

Developmental
–  Den7gerous Cyst

–  Odontogenic Keratocyst (Tumor – WHO)

–  Lateral Periodontal Cyst

–  Glandular Odontogenic Cyst

–  Calcifying Odontogenic Cysts (Gorlin’s Cyst)

112
Q

Arthrocentesis Advantages

A

• Minimally invasive • Fast, simple procedure – usually done in office • Does not require general anesthetic • Highly effective at increasing joint mobility, reducing pain

113
Q

BMP in young children can cause

A

cancer

114
Q

Determines quantity of bone that the graft will form.

A

Two-Phase Theory of Osteogenesis
 PHASE I

115
Q

Provide only passive framework or “scaffolding.”

A

Osteoconduction

116
Q

treatment for osteomyelitis

A

antibiotics-clindamycin

hospitization

117
Q

Two-Phase Theory of Osteogenesis
 PHASE I
is most active when

A

Most active within 4 weeks.

118
Q

when is block grafting ready for implant placement

A

4-6 months

119
Q

MANAGEMENT OF CYSTS (4)

A
  1.   Enuclea7on
  2.   Enuclea7on & cure]age (E&C)
  3.   Marsupializa7on

4.  Staged marsupializa7on & enuclea7on
(decompression technique)

120
Q

General
– Posture, body habitus, mood, affect, insight
• Note distinctives, in TMJ evaluation

A

“poor eye contact, spoke through
clenched teeth throughout interview,” etc.

121
Q

An inflammatory process of the bone marrow that involves cancellous and cortical bone with a tendency of progression.

A

osteomyelitis

122
Q

drug holidays are effective for bisphosphonates T./F

A

false While there have been limited studies on drug holidays for treatment of MRONJ, currently there have yet to be studies to confirm drug holidays are effective in prevention of MRONJ without increasing the skeletally related risks of low bone mass.

123
Q

correct uneven osseous/gingival levels

A

orthodontic eruption

124
Q

Recominate Bone Morphogenic proteins (BMP-2 and
BMP-7 have FDA approval)

A

Recombinate Grafts

125
Q

what is an all on four

A

2 angled parallel to sinus wall

2 in anterior

126
Q

name a good mnemonic for evaluating TMJ in pain history

A

L Location of the symptom (finger vs. hand) I Intensity of the symptom (scale 1-10)

Q Quality of the symptom (e.g. burning, pulsating,
ache) O Onset of the symptom + precipitating factors R Radiation of the symptom (“show me where”)

A Associated symptoms (joint sounds, other
neurological oddities) A Alleviating factors (avoid jaw function, etc.) A Aggravating factors (chew, sing, talk a long time)

127
Q

Staged marsupializa*on & enuclea*on • Advantages

A

–  Develops a thickened cys7c lining
–  Reduces morbidity and accelerates complete healing
–  Same as for marsupializa7on
•  Simple to perform •  Can save vital structures •  Completely resolves lesion or makes it smaller and easier to
treat and reconstruct

128
Q

Formation of new bone from osteoprogenitor cells.

A

Osteogenesis

129
Q

clinical stage 2 MRONJ treatment

A

§  Oral antimicrobial rinses §  Antibiotic therapy

130
Q

protrusion in TMJ translates

A

both joints

131
Q

  Epithelial
tumors (4)

A
  1.   Ameloblastoma
  2.   Adenomatoid odontogenic tumor
  3.   Calcifying epithelial odontogenic tumor (Pindborg)
  4.   Squamous odontogenic tumor
132
Q

– A screen for gross joint pathology and other
potential problems for TMJ eval

A

Panoramic Film

133
Q

Decreases intracys7c pressure

A

Marsupializa*on

134
Q

three ways to vertically augment bone

A

distraction osteogenesis

orthodontic eruption

sinus augmentation

135
Q

Superficial involvement, only Cortical bone exposed
treatment?

A

stage 1 osteoradionecrosis

Conservative : Chlorhexidine MW

136
Q

dry socket shoud not last longer than what

A

Dry socket does not last for more than a
week. Think something else!!! - REFER (could be osteomyelitis)

137
Q

Enuclea*on •  Advantages

A

–  Histopathologic examina7on of the en7re cys7c
wall

–  Ini7al biopsy/treatment is cura7ve in certain
situa7ons

138
Q

Mixed epithelial & ectomesenchymal
tumors

A
  1.   Ameloblas7c fibroma
  2.   Ameloblas7c fibro-odontoma
  3.   Odontoma
139
Q

Repair, revision, and/or
reconstruction of joint tissues (hard and soft)

A

Arthroplasty:

140
Q

how much bone is produced in the distraction phase of distraction osteogensis

A

1mm per day

141
Q

is horizontally augmentating ridges predictable or not predictable

A

• horizontally augmenting ridges: predictable

142
Q

Staged marsupializa*on & enuclea*on •  Indica7ons

A

–  Concern for injury to adjacent anatomical
structures

–  Size of lesion

–  Marsupializa7on alone does not resolve lesion

–  Need to examine en7re lesion histopathologically

143
Q

BMP-2=Infuse® has been approved for

A

BMP-2=Infuse® has been approved for sinus floor augmentation and grafting of mandibular defects

144
Q

name 3 IV bisphosphonates

A

¡  Aredia (pamidronate)
¡  Zometa (zolendronate)
¡  Reclast (zolendronate)

145
Q

– Press upward from when palpating the muscles in the TMJ area

A

– Press upward from pterygomandibular sling, note
radiation or distant site of pain (e.g. TMJ area,
whole side of head)

146
Q

what happens in the consolidation phase during distraction osteogenesis

A

active distraction complete

bony regenerate remodels into mature bone

147
Q

clinical stage 3 MRONJ

A

§  Exposed/necrotic bone
§  Pain
§  Infection
§  One or more of the
following: ▪   Fracture, extra-oral fistula,
oro-nasal communication.
osteolysis

148
Q

augment horizontal dimension of alveolus

A

block grafting

149
Q

Open a cys7c lesion and maintain patency to an
adjacent cavity

A

Marsupializa*on

150
Q

Extremely limited, unchanging ROM may indicate
in TMJ area

A

ankylosis

151
Q

drugs associated with MRONJ

A

1) bisphosphonates
2) anti-resorptive agents
3) anti-angiogenic medicatiosn

kinase inhibitors and monoclonal antibodies

152
Q

vertical augenting ridge predictable or non

A

nonpredictable

153
Q

Differentiation is influenced by bone inductive
proteins from the bone matrix.

A

Osteoinduction

154
Q

why is it difficult to obtain vertical augmentation

A

due to pressure from soft tissue envelope or a prosthesis

155
Q

Calcifying odontogenic cyst (Gorlin’s) managmenet

A

•  Enuclea7on and cure]age

156
Q

Enuclea*on & cure1age Disadvantage

A

Damage to neurovascular bundle

–  Dental pulps stripped

157
Q

Allografts/Homografts
have what type of graft

A

Osteoconductive

158
Q

extraoral donor site that provides a large quantity of bone

A

iliac crest

159
Q

Staged marsupializa*on & enuclea*on •  Disadvantages

A

Same as for marsupializa7on
•  Pa7ent inconvenience •  Occasional secondary infec7on •  Cannot histologically examine the en7re cys7c wall
–  However, secondary enuclea7on can remedy this concern

160
Q

– maintains con7nuity at inferior
border resection technique

A

Marginal

161
Q

Fibrous connec7ve 7ssue (CT) wall allows a cleavage
plane between lesion and bony cavity

A
  1. Enuclea*on
162
Q

inadequate adaptation and/or fixation of the bone graft to recipient bed

A

concerns with vertical augmentation by grafting

163
Q

how to palpate the masseter origin

A

Palpate posterior maxillary vestibule
• Lateral/posterior

164
Q

Remodeling process continues indefinitely.

A

Two-Phase Theory of Osteogenesis
 PHASE II

165
Q

in enucleation use the largest curette that will allow

A
  •   Cleavage plane
  •   Concave surface toward bone
166
Q

stage 2 MRONJ

A

§  Exposed/necrotic bone §  Pain §  Infection

167
Q

zygomaticus implants are placed where

A

through the palatal aspect of the maxillary crest transantrally into the compact bone of the zygoma

168
Q

iv indications for bisphosphonate rlated osteonecrosis of the jaws

A

IV ¡  Bone metastases associated with solid
tumors

¡  Hypercalcemia of malignancy

¡  Multiple myeloma

169
Q

what is denosumab

A

anti-resorptive agent

170
Q

Indications for Arthroscopy

A

Indications for Arthroscopy • Pain and dysfunction with the following conditions:
• Decreased condylar translation due to disk hypomobility • Anteriorly displaced disk with or without reduction • Closed lock • Traumatic injury

171
Q

how should monitor after enculeation ( in general practitioner office)

A

May require close follow-up with periodic panoramic
radiograph (every 6 months)

172
Q

general stiffness in TMJ area can mean

A

muscular influences

173
Q

Opening cyst to oral cavity (marsupializa7on) and
surgical plan is to make the cyst smaller (decompression) for final E&C at a later date

A

Staged marsupializa*on & enuclea*on

174
Q

•  Second surgery after recurrence when 1st
surgery (enuclea7on) was deemed cura7ve use what procedure

A

Enuclea*on & cure1age

175
Q

Two-Phase Theory of Osteogenesis
 PHASE II
begins

A

Begins at 2 weeks and peaks around 6 weeks.

176
Q

diagnosis of MRONJ

A

Ø  Current or previous treatment with a
bisphosphonate

Ø  Exposed bone in the maxillofacial region that
has persisted for more than Eight weeks

Ø  No history of radiation therapy to the jaws

177
Q

Inflammatory 1.  Periapical
cyst management

A
  •   Remove underlying process – RCT or extrac7on
  •   Enucleate +/- cure]age
  •   An7bio7cs if necessary
178
Q

bSynthetic analogs of inorganic pyrophosphate How do they work?
¡  High affinity ——–
¡  Inhibition of ——-
¡  May inhibit ———

A

Synthetic analogs of inorganic pyrophosphate How do they work?
¡  High affinity for Ca2+
¡  Inhibition of osteoclasts
¡  May inhibit capillary neo-angiogenesis

179
Q

Name 2 Inflammatory cysts

A

– Periapical Cyst – Residual Cysts

180
Q

Glandular odontogenic cyst
managmenet

A
  •   Enuclea7on and cure]age
  •   Some advocate more aggressive treatment (resec7on)
181
Q

post-op care after bone grafting

A

diet mods

temporary prosthesis-non load bearing/limit wear

oral hygiene

182
Q

oral indications for bisphosphonates

A

osteoporosis/osteopenia

paget’s disease

osteogenesis imperecta

183
Q

Den7gerous cyst
managment

A
  •   Extrac7on of affected tooth + E&C
  •   If larger – consider staged marsupializa7on and E&C
184
Q

what is enucleation good for

A

–  Den7gerous cyst

–  Periapical cyst

185
Q

Two-Phase Theory of Osteogenesis
 PHASE II
__________ is resorbed and replaced by __________. As the initial graft is resorbed, __________are released from the matrix.

A

Initial woven bone is resorbed and replaced by lamellar
bone. As the initial graft is resorbed, bone morphogenic proteins are released from the matrix.

186
Q

receiving IV bisphosphonates

A

Avoid osseous surgery if
possible!

187
Q

minimum required distance between implant and indicated struction for buccal + lingual plate

A

1mm

188
Q

– Indirect load to lateral pterygoids
indicates what when examining the TMJ area

A

• Press chin area posteriorly and/or superiorly against
resistance with mouth half open (half of patient’s best
opening)

Note presence of pain in preauricular area (TMJs) or
deep under cheekbone (lateral pterygoid)

189
Q

tx of tumors in medically compromised pts

A

Enucleation & Curettage of Jaw Tu m o r s

190
Q

– Best for suspected bony abnormality, i.e.
ankylosis, severe arthritis

A

CT

191
Q

Effusions in TMJ joint are strongly associated with

A

Effusions are strongly associated with ADD (+/-
reduction) and pain

192
Q
Sole treatment (rarely) or as a preliminary step 
before defini7ve enuclea7on of the smaller cyst
A

Marsupializa*on

193
Q

Asymptomatic patient taking oral BP > 4 years

A

: Drug holiday for 2 months.

194
Q

In osteoinduction, host cells must be stimulated to differentiate into the _______ by ______ and ______.

A

Host cells must be stimulated to differentiate into the
osteoblasts by transplanted growth factors and
cytokines.

195
Q

Incision into the joint

A

Arthrotomy:

196
Q

Marsupializa*on •  Advantages

A

–  Simple to perform
–  Can spare vital structures
–  Either completely resolves lesion or makes it
much smaller and easier to treat and reconstruct

197
Q

The Gold Standard
of grafts

A

Autografts

198
Q

Two-Phase Theory of Osteogenesis
 PHASE II
 ___________________ from the
graft bed begin after grafting, and________ from host connective tissue soon begins.

A

Angiogenesis and fibroblastic proliferation from the
graft bed begin after grafting, and osteogenesis from host connective tissue soon begins.

199
Q

ADD is frequently found in asymptomatic control
populations what percent

A

(12-45%)

200
Q

about to receive IV bisphosphonates

A

Get healthy before!

201
Q

Does NOT demonstrate joint space reliably

A

Panoramic Film

202
Q

  Asymptomatic patient taking oral BP ¡  Sound recommendations are still lacking
§  <4 years

A

proceed with planned treatment

203
Q

common reasons of compromised wound healing

A

medications

radiotherapy

infection

systemic disease

204
Q

minimum distance between implant and mx sinus/ nose

A

1mm

205
Q

Diffuse involvement including inferior border. Usually associated with pathologic fracture and possible osteo-cutaneous fistula
treatment

A

stage 3 osteoradionecrosis

Surgical resection and reconstruction

206
Q

what happens during the distraction phase of distraction osteogenesis

A

osteoblast induction

woven bone formation

207
Q

¡  Patients about to begin IV therapy
for bisphosphonates how to manage

A

¡  Patients about to begin IV therapy
§  Delay therapy, if systemic conditions permit
§  Optimize oral health prior to initiating therapy
§  Allow adequate osseous healing and wait until the
surgery sites become mucosalized (14-21 days)

208
Q

Grafts transplanted between individuals of different
species (i.e. bovine bone/Bio-Oss)

A

Xenograft

209
Q

indirect sinus augmentation yields how much bone

A

4mm of bone

210
Q

BMP (Bone Morphogenic Protein)
acts on _______ to induce differntiation into

A

Acts on progenitor cells to induce differentiation into
osteoblasts.