Final Flashcards
Heart failure classification
Comfortable at rest
Slight limitation of physical activity
Class II mild
Heart failure classification
Marked limitation of physical activity
Less than ordinary activity results in fatigue, palpitation, or dyspnea
Class III. Moderate
Heart failure classification
Symptoms of cardiac insufficiency at rest
Unable to carry out any physical activity without discomfort
Severe
Class IV
Type of cardiomyopathy
Systolic dysfunction
Eccentric LV enlargement
Dilated (congestive) cardiomyopathy
Type of cardiomyopathy
Diastolic dysfunction
Concentric hypertrophy
Dynamic outflow obstruction
Obstructive cardiomyoptahy
Abnormal diastolic dysfunction.
Abnormal E:A
Restrictive cardiomyopathy
Failure of LV leads to increased ____________
LVEDP
LVH
Best vasopressor for heart failure patient
Ephedrine better than phenylephrine
NE better than ephedrine
Vasopressin if cant get NE
Highest mortality post transplant is when
Within first 6 months
90% of heart transplant is due to
Idiopathic or ischemic dilated cardiomyopathy
6 contraindications to heart transplant
Severe elevation in PVR
Psych factors/compliance
Irreversible renal, hepatic, pulmonary function
Co-existing disease with poor prognosis
Uncontrolled malignancy
Active infectious process
Minimize ischemic time of donor heart. Usually less than
4 hours
Donor heart is denervated and electrical activity
ECG appearance
Cannot cross suture line
2 P waves
Due to denervation which sympathomimetic have no effect
Indirect bc loss of SNS, PNS innervation to heart
Use direct: epi, NE, isoproterenol
Management of RV failure after transplant (4)
Optimize preload (starling pyramid)
Provide early inotropic support
Maintain low PVR
Consider mechanical support (IABP, RV assist device)
3 drug classes ot maintain low PVR
Nitrates
Prostaglandins
Nitric Oxide
Post transplant considerations for anesthesia
No hemodynamic response to DL and light anesthesia and pain
Induction in heart failure patients (3)
Slower induction
Maintenance of compensatory mechanisms
More potent vasopressors
4 indications for VADs
Heart failure
Circulatory support during surgery
Recovery from MI
Destination therapy
LVADs are dependent on
Reasonable RV function
Normal PAP
Often used to improve pulmonary hypertension and RV function
Epoprosterenol (Flolan)
Nitric oxide
TEE findings that contraindicated LVAD placement
AI
PFO
VSD
ASD
Severe RV dysfunction
Unique considerations of VAD hemodynamics
Inconsistent LV ejection
Use MAP instead of SBP/DBP
Optimize RV function
Current durable VADS have _______ flow
Non-pulsatile continuous flow
What 2 things decrease LVAD flow
Hypovolemia and increased afterload
TEE exam after LVAD implantation watch for
SUCKDOWN
Need adequate preload
Post-implantation management of LVAD includes
Anticoagulation
Avoid high pump speeds
Prior to surgery should assess
Patient function
End organ damage
Doppler/US available
Anesthesia plan for pt with LVAD
Faster fuller vasodilation
Post implant LVAD hemodynamic goals
MAP
Pulse pressure
MAP 70-80. Avoid >90mmHG
PP 10 mmHG
No _________ for LVAD patients
Spinal or epidural
Anesthesia for LVAD patients
Avoid hypovolemia and pulmonary hypertension
If in doubt about pump function during arrest you should do what?
Listen for humming