Final

Question 1

Atracurium

Answer 1

BB (NMB) Intermediate
Hoffman elimination
Yes Histamine release
Protein bound (most NMB are not)
Inactive at NMJ

Question 2

Mivacurium

Answer 2

BB (NMB) Fast
No Hoffman elimination
Yes Histamine release
Bronchospasm
Hydrolyzed by p. cholinesterase

Question 3

Cisatracurium

Answer 3

• BB (NMB) Intermediate
• Hoffman elimination
• No Histamine release
• Good to give with renal/hepatic impairment
• Inactive at NMJ

Question 4

Pipecuronium

Answer 4

BA (NMB) Long

No CV effects

Question 5

Doxacurium

Answer 5

(NMB) Long

No CV effects

Question 6

Pancuronium

Answer 6

BA (NMB) Long

Question 7

Vecuronium

Answer 7

MA (NMB) Intermediate

Hepatic/ biliary elimination

Question 8

Quaternary Ammonium

Answer 8

No CNS effects
> ionized/>H20 soluble
All injectable meds

Question 9

Rocc

Answer 9

(NMB) Intermediate
Vagal effects
Biliary elimination

Question 10

Succ

Answer 10

(NMB) Fast
>Gastric, ocular, brain
Hydrolyzed by p. cholinesterase
< HR, arrest
Rest and digest
Cardiac muscarinic receptors

Question 11

Atropine

Answer 11

Anticholinergic (Mu 3 bronchodilation)
Give for anticholinesterase OD
Will cross BBB

Question 12

Physostigmine

Answer 12

Anticholinesterase? (M3 bronchodilation)
Give for central anticholinergic OD
Will cross BBB

Question 13

Scopolamine

Answer 13

Anticholinergic (Mu 3 bronchodilation)
Will cross BBB
Weakest smooth muscle relaxant

Question 14

Glycopyrrolate

Answer 14

Anticholinergic (Mu 3 bronchodilation)
Will not cross BBB (NH4)
Semi synthetic

Question 15

Neostigmine

Answer 15

Anticholinesterase
Onset 7-11 min
Post synaptic
> p. cholinesterase

Question 16

Pyridostigmine

Answer 16

Anticholinesterase
Onset 16 mins
Post synaptic
> p. cholinesterase

Question 17

Endrophonium

Answer 17

Anticholinesterase
Onset 1-2 mins
Pre synaptic
No > in p. cholinesterase

Question 18

IA HR

Answer 18

Sevo NONE
Des >
Iso >
N2O >

Question 19

IA BP effects

Answer 19

Iso «<
Des «
Sevo <
N2O - >

Question 20

Most CO2 with IA

Answer 20

Des most

Iso

Question 21

Coronary steal IA

Answer 21

Iso

Question 22

Epileptoform IA

Answer 22

Sevo

Question 23

Longest to shortest IA to wake up

Answer 23

Hal
Iso
Sevo
Des
N2O

Question 24

Don’t give what IA with B12 deficiency?

Answer 24

N2O

Question 25

> PVC Risk IA

Answer 25

Halo

Question 26

Don’t use _____ for Hx > QT

Answer 26

Sevo