Final Flashcards
Metabolite
Compound found in metabolism
ATP synthase
Enzyme used for producing ATP
Hypercholesterolemia
Very high cholesterol at birth
Anabolism
Build up of biomolecules
Catabolism
Breakdown of biomolecules
Gout
Excess uric acid in joints
Kwashiorkor
Body breaks down own proteins
Phenylketonuria
Can’t metabolize phenylalanine
Albinism
Can’t convert tyrosine to melanin
Lesch-nyhan syndrome
Self mutilation
Tay sachs disease
Error in lipid metabolism
Glyoxysomes
Organelle found in plants
Lipases
Enzyme to break down triglycerides
Oxidation
Loss of electron
Reduction
Gain of electron
Decarboxylation
Removal of CO2
Dehydration
Removal of water
Hydration
Addition of water
Phosphorylation
Exchange of phosphate
Isomerization
Change conformation not formula
Redox
Exchange of electrons
Hydrogenation
Addition of H2 to double bond
Hydrolysis
Breaks double bond and adds H and OH
Monosaccharides
Single simple sugar
Oligosaccharide
Short chain of simple sugars
Polysaccharide
Long chain of simple sugars
Isomer
Same chemical formula, different structures
Enantiomer
Mirror image
Entropy
Randomness
Enthalpy
Heat energy
Gibb’s free energy
G
Diastereomer
Non mirror images
Sucrose
Glucose and fructose
Glucose
Dextrose
Fructose
Fruit sugar
Lactose
Glucose and galactose
Xylose
Five carbon sugar
Maltose
Glucose alpha bond
Cellulose
Glucose beta plant
Cellobiose
Glucose beta
Starch
Glucose alpha link plant
Glycogen
Glucose alpha link animals
Forms of starch
Amylose and amylopectin
Amylose
Straight chain polymer
Amylopectin
Branched chain polymer
Bonds that hold monosaccharides together
Glycosidic bonds
Type of reaction for kinase
Phosphorylation and phosphate
Type of reaction for dehydrogenase
Dehydrogenation NAD and FAD
Step one and three of glycolysis
Phosphorylation
Kinase
ATP
Step two of glycolysis
Isomerization
Isomerase
Gluconeogenesis
Pyruvate to oxaloacetate to phosphoenal pyruvate
1-3 irreversible: need phosphotase to reverse
When and why is lactate produced in muscles ?
When energy production is required faster than our bodies can deliver oxygen
Pyruvate is reduced to lactate to break down glucose
So high levels of lactate are produced
Overall Rxn of pyruvate before TCA cycle
Oxidative decarboxylation to produce acetyl CoA
ATP difference for glycolysis and gluconeogenesis
Gluconeogenesis uses ATP to regenerate glucose so there is a loss of energy
Glucose:pyruvate
1:2
Step six of glycolysis
Phosphorylation and redox rxn
Kinase and dehydrogenase
Step nine of glycolysis
Dehydration
Steps 3 and 6 of TCA cycle occur where?
Intermediate space
Step 1 rxn of TCA
Condensation
Step 2 rxn of TCA
Isomerization
Step 4 rxn TCA
Decarboxylation
Step 7 rxn TCA
Hydration
Two mechanistic theories for electron transport
Chemiosmotic coupling: high H causes to enter ATPase and produce ATP
Conformational coupling
Step one B oxidation
Fatty acid reacts with CoA to produce acyl CoA
Flows through outer membrane
Step 2 B oxidation
Splits apart in intermembrane
Acyl reacts with carnitine to produce acylcarnitine
Flows into matrix
Step 3 B oxidation
Splits apart
Acyl reacts with CoA to produce AcylCoA
Common product of fatty acid anabolism
Palmitic acid
Product of even numbered FA breakdown
Acetyl CoA
Product of odd numbered FA
Propionyl CoA
Overall purpose of steps 5-8 TCA
Reproduce oxaloacetate