Final Flashcards
how many mutations in a single colon cell
5-10
what is the likelihood of a monozygotic birth
1/500
DZ -> 1/100
what family does RAS belong to
oncogene
what protein does both hypercholesterolemia and Alzheimer’s have
Apo E
what protein associated with hypertrophic cardiomyopathy
alpha tropomyosin
when mom eats like shit then baby is fat
metabolic imprinting
when a bacterium picks up new genes
transgenic modification
what type of mutation is huntingtons
autosomal dominant
cancer families
mutations occur in germline
what is associated with ERBB and lung carcinoma and glioblastoma
oncogene
what is associated with MLH1 and nonpolyposis colon cancer
DNA mismatch repair gene
what bonds broken at 95 degrees in PCR
polymerase chain reaction
something about what can be measured on a continuous scale
quantitative
when someone gets back a test result saying they dont have the diease they feel
guilt
trophoblasts are taken during what procedure
chorionic villus sampling
how to screen for down sydrome noninvasively and accurately
triple
some question about cost effectiveness of genetic testing
BRCA $3000
why do we use a polymerase from thermos aquaticus
works at high temps
expression of polymorphs can be in a variety of forms except
the drug
if you have high cyt p450
ultra rapid metabolizer
how drug effects body
pharmacodynamics
FAS an apoptotic gene
extrinsic pathway
what gene is associated with schizophrenia
dysbindin, neuregulin 1, G72
alkaptonuria
homogentisic acid oxidase; tyrosine catabolism
OTC
x-linked; most common urea cycle disorder
menkes
copper def.; x linked
anderson
branching enzyme
