final Flashcards

1
Q

What part of the cell cycle is division of genetic information

A

Mitosis

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2
Q

what phase does replication of organelles occur?

A

G1 phase

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3
Q

if a cell is in G0 phase, does it reenter the cell cycle whenever it wants too?

A

false

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4
Q

During what phase does kinetochore microtubules attach to the kinetochore?

A

Prometaphase

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5
Q

All cells are able to divide through their entire life span? t/f?

A

false

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6
Q

Pick two that work together to regulate cetain phases of the cell cycle?
Quiescence, Cyclins, Cyclin dependent kinases, CIP

A

Cyclins and Cycling dependent kinases

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7
Q

The restriction point does which of the following jobs?

A

Prevents progression to DNA synthesis

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8
Q

During what phase does the nucleolus disappear?

A

Prophase

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9
Q

Human papollimavirus deactivates which two tumor suppressor genes?

A

P53 and BRCA1

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10
Q

if a cell becomes damaged, and if DNA is altered or damaged, what stage is it most likely stopped at to fix it?

A

G1

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11
Q

Cdc25c may be inhibited by what tumor suppressor protein? ( their are two)

A

RB AND TP53

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12
Q

Which cyclin will kinases CDK1 to transition from G2 to M?

A

Cyclin B

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13
Q

T/F A senescent cells is permanently stuck in G0.

A

T

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14
Q

T/F Cells are killed off but are replaced at the same time to maintain homeostasis.

A

T

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15
Q

What theory allows for limitless replication?

A

Stem Cell Theory

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16
Q

If a cancer follows ___, it is more likely to be resistant to drugs.

A

Stem Cell Theory

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17
Q

What is the correct order of the process of cancer?

A

Initiation- promotion- progression- metastasis

18
Q

What are some hallmark of cancer?

A

Self-sufficient growth
Angiogenesis
Ignores anti-growth signals

19
Q

Li-Fraumeni syndrome is a mutation of what gene?

A

TP53

20
Q

Which gene functions in cell adhesion?

A

APC

21
Q

Which of the following statements is not true regarding apoptosis?

1) No damage to cells around
2) Relatively short process
3) Due to injury
4) No inflammation

A

No damage to cells around,
Relatively short process
No inflammation

22
Q

T/F most of the time apoptosis is bad.

A

false

23
Q

What signals the apoptosome complex in the cytoplasm?

A

Cytochrome C

24
Q

What is the function of caspase 3?

A

Effector caspase

25
Q

cancer can be described as

A

Overexpression of apoptotic protein

26
Q

Which hallmark of aging is described as having abnormal protein accumulation?

A

Loss of protein homeostasis

27
Q

What hallmark of aging alters transcription?

A

Epigenetic alterations

28
Q

T/F Eukaryotic cells can divide indefinitely.

A

False

29
Q

T/F senescent cells do not replicate because they are not metabolically active anymore

A

False

30
Q

T/F action potentials A spread unidirectionally

A

True

31
Q

During what stage of an action potential will there be an efflux of K+

A

Repolarization

32
Q

Which channels initiate action potential and are typically fast?

A

Sodium Channels

33
Q

T/F If at some point during a nerve action potential cannot generate enough voltage, depolarization spread will stop.

A

True

34
Q

Activation of sodium and potassium pump is dependent on ____

A

Sodium

35
Q

what is an example of an anion?

A

Calcium

36
Q

Histamine is an example of what class of neurotransmitter?

A

Class II

37
Q

what are some examples of pairing? (3)

A

Dopamine- substania nigra
Acetylcholine- motor cortex
Glutamate- cerberal cortex

38
Q

T/F all neurotransmitters are stored in vesicles

A

False

39
Q

What will strychnine do to synaptic transmission?

A

Reduce threshold

40
Q

T/F oncogenes control cell growth and differentiation

A

false

41
Q

which part of the cell cycle is when two daughter cells are given off?

A

Interphase