Final Flashcards

1
Q

Most common estrogen component in hormonal birth control:

A

Ethinyl estradiol

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2
Q

Who makes the guidelines for contraception?

A

CDC

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3
Q

What form of estrogen is used after menopause?

A

estradiol valerate

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4
Q

What does HB2879 say?

A

That a pharmacist may prescribe and dispense hormonal birth control to anyone over age 18 w/o evidence of a prior prescription or someone under age 18 with evidence of a prior prescription.

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5
Q

What does a pharmacist have to so in order to become certified to prescribe hormonal birth control?

A

Complete a training program approved by the board of pharmacy
Provide a self-screening tool to the patient
Refer the patient to their women’s health care practitioner.
Provide the patient with a record of their prescription.

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6
Q

Can a pharmacist prescribe hormonal birth control for a patient that they prescribed to three years ago if they have not visited a women’s health provider since then?

A

No. However, the patient may be tricky and go to the pharmacy across the street to get it prescribed.

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7
Q

Can insurance cover this birth control?

A

Yes.

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8
Q

What has to be ACPE accredited?

A

The pharmacist training must be ACPE accredited.

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9
Q

What is a difference between pharmacists and doctors prescribing to self and family members?

A

Doctors are recommended not to, while pharmacist are prohibited from prescribing to self and family members.

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10
Q

What subjects are covered in the pharmacists training program?

A
Foundation for women's health
Pharmacology
Therapeutics
Patient Self-Assement
Workflow
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11
Q

What contraception method is most widely used?

A

The pill, while male condom comes in second. The 1st line option, the IUD is only 10% of the contraception used.

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12
Q

Is the rate of VTE higher for birth control, during pregnancy, or during postpartum?

A

VTE risk is the highest postpartum, second-highest during pregnancy, and third-highest while on OC’s.

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13
Q

What percentage of pregnancies are unintended?

A

50%

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14
Q

What did the Direct Access Study do?

A
  • 2008
  • Used a validated self-assessment questionnaire
  • Collaborative practice agreement
  • It was determined that pharmacist could effectively screen women and provide birth control. Women and pharmacists were satisfied.
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15
Q

What laws do Colorado, Washington, and California have in place regarding pharmacists providing birth control?

A

Washington has a window sticker law. California and Colorado have a state protocol that is identical to Oregon’s protocol. New Mexico also has a state protocol, while Missouri and Tennessee have a CPA.

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16
Q

What is US MEC?

A

Medical Eligibility Criteria

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17
Q

What are the categories for eligibility for contraceptive use?

A
  1. No restrictions
  2. Benefits usually outweigh risks
  3. Risks usually outweigh benefits
  4. Unacceptable health risk if contraceptive is used
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18
Q

What has the self-assessment questionnaire shown?

A

That women are capable of assessing their own risk more than a provider. However, OTC status is not a good idea, as studies have to be done first.

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19
Q

What are the patient-care centered steps?

A
Collect
Assess
Plan 
Implement
Follow-up
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20
Q

How much medication can you give the patient?

A

Initially, 3 months worth. Then another 9 months. The more medication you can give the patient, the more adherent they will be.
For continuing ex’s, can do 12 months.

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21
Q

What important documents are needed?

A
Standard procedures algorithm
Self-Screening questionnaire
Rules and regulations
policies and procedures
Patient visit summary
US MEC
List of nearby clinics for referral
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22
Q

What steps are required in order to prescribe someone birth control as a pharmacist?

A
  1. Health and history screen
  2. Pregnancy screen (period w.i last 7 days, 6 month old baby w/ no periods, abstaining since last period, using a contraceptive method consistently and correctly, etc.)
  3. Medication screen (cabamezepine, phenytoin, phenobarbital, primidone, topiramate. NOT St. John’s wort)
  4. Blood pressure (<140/90)
  5. After-visit summary may be provided, or circle referral instead, where it will have you list the reason. Provide list of nearby clinics.
  6. Discuss initiation strategy for treatment/change in treatment (counsel on starting now, using backup for 7 days, SE of bleeding irregularities, adherence, follow-up)
  7. Discuss and provide referral or visit summary.

**Pharmacy has to retain a cope of AVS and questionnaire, and send a copy to the PCP if they have one. Will still collect a fee.

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23
Q

What are the necessary things to counsel on?

A
Take by mouth
At same time every day
Set up first pill back
Start ASAP and use backup if needed for 1 week.
Placebo week, or not
When follow-up is needed
Hormonal contraception does not protect against STI's
Some drug interactions
Adherence is very important
Have back-up method on hand (condoms)

Expect:
Common- breakthrough bleeding for about 3 months
Serious - blood clots (five people in 10,000)
If side effects don’t go away, there are alternate formulations

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24
Q

What types of patients should be referred to a women’s healthcare provider?

A

No insurance - refer to free clinic

Contraindications

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25
Q

What do pharmacies need to have to for a pharmacist to prescribe hormonal contraceptives?

A

A pharmacist’s NPI needs to be changed to a pharmacist clinician.
Certify their pharmacists as providers with each insurance company
Some have software to interface pharmacy systems with billing.

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26
Q

Do you bill pharmacy or medical coverage for prescribing birth control?

A

Medical coverage

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27
Q

What is antimicrobial stewardship?

A

It is a professional role in infectious control. They make sure that inappropriate prescribing is not going on to curb resistance.

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28
Q

What is the difference between bacteriostatic and bactericidal? Which is more important for getting the right dose?

A

Bacteriostatic stops growth, while bactericidal kills bacteria. Bactericidal is more important for getting the right dose.

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29
Q

What is important to ask about allergies?

A

What the reaction was it, and how long ago was it?

30
Q

What are the “when in doubt” antibiotic counseling points?

A

May cause n/v/d and GI upset
Drink with a full glass of water
Complete full course of therapy despite feeling better
Look for s/s of hives, rash, difficulty breathing, and other s/s of allergic reactions (hypersensitivity reaction causes allergy 2nd time)

31
Q

What are the skin organisms?

A

Gram positive.

Either strep or staph. Penicillin will probably fail to treat skin infections.

32
Q

What would you cover for when treating a bug in the gut?

A

Gram negative anaerobes

33
Q

What normally causes UTI’s?

A

E. coli

34
Q

What bugs normally cause pneumonia?

A

Staph and strep

35
Q
Gram positive bacteria:
Stain - 
Periplasmic space - 
Cell wall thickness -
Porin channels- 
Analogy - 
Examples -
A
Stain - Pink
Periplasmic space - Small
Cell wall thickness - Thick
Porin channels- Mostly absent
Analogy - Thick fence
Examples - strep, staph, enterococcus
Thick peptidoglycan layer
36
Q
Gram negative bacteria:
Stain - 
Periplasmic space - 
Cell wall thickness -
Porin channels- 
Analogy - 
Examples -
A
Stain - purple
Periplasmic space - big
Cell wall thickness - thin
Porin channels- common
Analogy - kevlar vest
Examples - pseudomonas
Thin peptidoglycan layer
37
Q

Which type of bacteria is harder to kill?

A

Gram negative bacteria

38
Q

What are ways of developing resistance for the bacteria?

A
Deactivate drug through beta lactamases
Have active efflux channels
Change binding sites
Make the cell wall impenetrable
Can change metabolic pathway despite what antibiotics are doing
39
Q

MOA - Beta lactams

A

Inhibit cell wall synthesis

40
Q

What generation of beta-lactams will treat MRSA? Pseudomonas?

A
5th gen (Ceftaroline) will treat MRSA
4th gen and Ceftazidime will treat pseudomonas
41
Q

1st gen cephalosporins

A

PEcK

Proteus, E. coli, Klebsiella

42
Q

2ns gen cephalosporins

A

HEN PEcK
H. influenza, Enterobacter, Neissera
Proteus, E. coli, Klebsiella

43
Q

3rd gen cephalosporins

A

HEN PEcK CAMPS

Citrobacterm Acinetobacter, Morganella, Pseudomonas

44
Q

4th gen cephalosporins

A

HEN PEcK CAMPS + Provendencia

45
Q

5th gen cephalosporins

A

HEN PEcK CAMPS + MRSA

46
Q

What will the Carbapenems cover?

A

Pseudomonas but not MRSA

47
Q

What could you use if you had a penicillin allergy?

A

Aztreonam, a monobactam.

48
Q

Cephalosporins are LAME

A

Do not have activity against Listeria, atypical, MRSA, Enterococci

49
Q

Which beta lactic can you take if you have liver problems?

A

Ceftriaxone

50
Q

Which two cephalosporins cover pseudomonas?

A

Cefepime and ceftazadine

51
Q

Which cephalosporin has activity against MRSA?

A

Ceftaroline

52
Q

What antibiotics inhibit 50s ribosomal protein synthesis?

A

Macrolides
Clindamycin
Linezolid

53
Q

What antibiotics inhibit the 30S ribosomal protein synthesis?

A

Aminoglycosides

Tetracycline

54
Q

What inhibits DNA topoisomerase IV and DNA gyrase?

A

Floroquinolones

55
Q

What antibiotics inhibit the folic acid pathway?

A

SMX/TMP

56
Q

What antibiotics use strand breakage to inhibit protein synthesis?

A

Metronidazole

57
Q

What inhibits cell synthesis? (D-Ala D-Ala)?

A

Nitrofurantoin

Vancomycin (D-Ala D-Ala)

58
Q

Which antibiotics do you get photosensitivity from?

A

Floroquinolones
SMX/TMP
Tetracycline

59
Q

Which antibiotic has the greatest risk of C. dif?

A

Clindamycin

60
Q

Which antibiotic is red man syndrome associated with?

A

Vancomycin

61
Q

Which antibiotics have to be monitored carefully due high risk of nephrotoxicity and ototoxicity?

A

Aminoglycosides

62
Q

What is the DOC for C. dif infection?

A

Metronidazole

63
Q

Which drugs have Q-T prolongation risks?

A

macrolides

floroquinolones

64
Q

Which drug has a black box warning for colitis?

A

Clindamycin

65
Q

What does vancomycin treat?

A

C dif in the PO form, not IV

66
Q

What drug do you have to be cautious with serotonin-increasing agents?

A

Linezolid

67
Q

What drugs cover pseudomonas?

A
Cefepime, ceftzadime
ciprofloxacin, levofloxacin
Imipenem, dirpenem, meropenem
Aztreonam
Aminoglycosides
68
Q

What drugs cover atypical?

A

Macrolides
Doxycycline
Fluoroquinolones

69
Q

What drugs cover anaerobes?

A
Metronidazole
Piperacillin/Tazobactam
Carbapenems
Clindamycin
Ampicillin/Sulfbactam
Augmentin
70
Q

What drugs cover MRSA?

A
CLindamycin
SMX/TMP
Tetracyclines
Linezolid
Vancomycin
Daptomycin
Telavancin
Oritavancin
Dalbavancin
Ceftaroline