Final Flashcards

1
Q

Diagnoses of Fibro-osseous lesions are determined via:

A

Radiographic and Clinical features

Histopathologic features are similar

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2
Q

Periapical Osseous Dysplasia is most commonly found where?

A

Anterior mandible (incisors)

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3
Q

Why are biopsies of Periapical Osseous and Florid Osseous Dysplasias not recommended?

A

Biopsy increases the risk of secondary infection due to reduced vascularity of these lesions

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4
Q

What is the major difference between Osseous Dysplasias and Ossifying Fibromas?

A

Ossifying Fibromas cause significant concentric expansion in all directions

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5
Q

What genetic abnormality accompanies 93% of Fibrous Dysplasia patients?

A

Mutation in GNAS1 gene on Chromosome 20q13.32

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6
Q

What is the typical radiographic appearance on Fibrous Dysplasia?

A

“Ground glass”

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7
Q

Which condition is linked to puberty?

A

Fibrous Dysplasia

  • Does not progress beyond puberty
  • 2-3% of Polyostotic form associated with McCune Albright syndrome = Precocious puberty
  • Polyostotic form usually presents before age of 10
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8
Q

Which Fibro-Osseous lesion is associated with nerve impingement?

A

Fibrous Dysplasia

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9
Q

What diseases are differential diagnoses for Fibrous Dysplasia?

A

Paget’s
Periapical cemental dysplasia
Osteomyelitis
Hyperparathyroidism

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10
Q

Which is the only Fibro-Osseous lesion that requires treatment?

A

Ossifying fibroma

- Surgical enucleation

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11
Q

Which is the most common malignant disease?

A

Carcinoma (epithelial origin)

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12
Q

What is the most common malignancy in oral cavity?

A

Squamous Cell Carcinoma

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13
Q

Which disease causes direct bone formation vs. reactive bone formation?

A

Osteosarcoma

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14
Q

Which malignancy can often occur in patients with Fibrous dysplasia or Paget’s disease after radiation therapy?

A

Osteosarcoma

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15
Q

Which malignancy has characteristic Bence Jones proteins in the urine?

A

Multiple Myeloma

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16
Q

Which syndromes are associated with multiple supernumerary teeth?

A

Cleidocranial dysplasia
Gardner’s syndrome
Pyknodysostosis

17
Q

What is the most common supernumerary tooth in the anterior maxilla?

A

Mesioden

18
Q

Which syndrome is associated with Oligodontia and Anodontia?

A

Ectodermal dysplasia

19
Q

Which syndromes are associated with Macrodontia?

A

Hemangioma
Hemihypertrophy of the face
Pituitary gigantism

20
Q

Which syndromes are associated with Microdontia?

A

Pituitary dwarfism
Congenital heart disease
Progeria

21
Q

Transposition is most common between which teeth?

A

Maxillary canine and 1st premolar

22
Q

Which tooth malformations is Congenital Syphillis associated with?

A

“Hutchinson’s incisors”

“Mulberry molars”