Final Flashcards
Adrenal Disease is caused by the interruption of the _______
PAG axis
What kind of hormones does the Adrenal Gland produce?
Sex Hormones Androgens - Progesterone -Estrogens -Anderostenedione - DHEAS
T/F: Most Ferrets do not experience Adrenal Disease.
FALSE
Most ferrets have adrenal disease
Hormone producing tumor in the ferret is described as ________
Hyperadrenalcorticism
-Hyperplasia
T/F: Hyperadrenalcorticism in the ferret is the same as Cushing’s Disease.
FALSE
T/F: Clinical signs of hyperadrenalcorticism in the ferret include: Hair loss, pruritus, smelly, sexual, swollen vulva
True Rat tail Hair Loss Big Nipples in males and females Swollen vulva esp if estrogen producing tumor Boys esp like the Sex!
What if you see a ferret with a SWOLLEN VULVA?
Think Adrenal- Estrogen producing tumor
or
Intact female in heat
Ferrets normally have small prostates. When do they enlarge? How do they appear
Dz- Adrenal Androgens
Become Cystic
T/F: The survival time with ferret adrenal disease is the same with medical & surgical txn.
True!
What is the goal to treating adrenal dz?
REDUCE SEX HORMONES
What can be used medically to reduce sex hormones in ferret adrenal dz cases?
Leuprolide monthly shots
The indication of end stage Adrenal disease in the ferret is ______
Patechial hemorrha
From long term estrogen tox causing BM suppression
T/F: The right adrenal gland in the ferret is embedded in fat
False
the left adrenal gland is embedded in fat
Which sx is mostly performed on the right adrenal gland in ferrets with adrenal dz?
Subtotal Adrenalectomy
It wraps aroudnt he dorsal surface of the vena cava. Other adrenal may be affected but do NOT take it out b/c may hit the vena cava
T/F: Leuprolide Acetate (Lupron) can be used in both ferrets and bird
True!
How does Leuprolide work and how long does it last?
GnRH agonist- stimulates LH/FSH
Stops steroidenesis and repro activity
Lasts ~ 1 month
How does Deslorelin compare to Lupron?
Same action
BUT last longer
However takes 3 weeks to set up so start with Lupron first then switch. Will save money
T/F: Insulinomas in ferrets can be cured completely
False!
Controllable, NOT curable
What signs do you see in ferrets with insulinoma?
Episodic weakness, Drooling, Weak rear end, Staring into space/Gazy eyes
What is the shock organ in ferrets?
Hind legs!
That’s why their rear end is weak when have insulinoma
How do you def diagnose insulinoma in ferrets?
Fasting glucose
How do you medically treat insulinomas in ferrets?
Maintain Blood glucose, Low carb diet
PREDNISONE= gluconeogenic
&
DIAZOXIDE= insulin blocker
The first line of txn in insulinoma ferret?
Predinosone- start at low dose
Good prognosis
Why would you use Famotidine in ferrets with insulinoma?
Nausea
If can get them to eat, they will feel better
(But ferrets prefer pediapred)
What pancreatic sx can be performed in ferrets?
Nodulectomy
Lymphosarcomas are common and are found where in the ferret?
ANYWHERE
young & older ferrets, multicentric, lymphadenopathy
varying prognx
Majority ferret skin tumors are benign. What kind of tumors are these?
Mast Cell tumors
Can be itchy & bloody
Remove with sx, freeze, cryocaine
Good prognx but txn lasts a few months and can relapse
What type of lymphoma is hard to treat in ferrets?
Retrobulbar
where eyes bulge out
Why would you have a big spleen in the ferret?
Extramedullary hematopoiesis
also bloody spleen with some white areas
The Trifecta of lymphomsarcoma in young ferrets esp is ____, _____, and ______
Mediastinal mass, big liver (hepatomegaly), and big spleen (splenomegaly)
T/F: Ferret spleen size is not synchronous with dz
True!
Tissue biopsy, aspirate are used to dx lymphosarcoma?
Yes
T/F: Cyclophosphamide, Vincristine, and Prednisolone can be used to treat Lymphosarcoma
True!
sx debulk also
cyclophosphamide= oral
vincristine= IV once/month
Prednisolone= oral
T/F: Ferrets do NOT get CV dz
False
Get BOTH types of Cardiomyopathy= DCM and HCM
What other CV dz can ferrets get besides cardiomyopathy?
Heartworms
Ivermectin as prevention!
T/F: Ferrets are at the top so they are fearless
True!
T/F: Rabbits are scary
True!
they are prey to others so they try to hide out & are unpredictable
T/F: Rabbits are rodents
False!
They are Lagomorphs