FINAL Flashcards
Antiulcer. To treat GERD and gastric ulcers. Interferes with gastric acid secretion.
Omeprazole
Antiulcer, gastric acid proton pump inhibitor. To treat GERD and erosive esophagitis. Interferes with gastric acid secretion.
Pantoprazole
Antiulcer agent, gastric acid secretion inhibitor. Short-term treatment of duodenal ulcers, benign gastric ulcers, heartburn and indigestion, and GERD. Prevents histamine from binding with H2 receptors on the surface of parietal cells, thus helping to prevent peptic ulcers and to heal existing ones.
Famotidine
Antigout. To treat gout and hyperuricemia, gout attack, prevent uric acid nephropathy, and recurrent calcium oxalate calculi. Inhibits uric acid production.
Allopurinol
Antitussive, opioid analgesic. To treat mild to moderate pain, cough from chemical or mechanical irritation. Prevents the release of pain neurotransmitters, altering perception of and emotional response to pain, acts on opiate receptors in the cough center to suppress cough
Codeine
Analgesic. To manage severe pain in opioid-tolerant patients. Binds to and activates opioid receptors in gray matter, medulla and the spinal cord to produce pain relief.
Hydrocodone
Antipyretic, non-opioid analgesic. To relieve mild to moderate pain, to reduce fever. Interferes with pain impulse generation in the PNS and acts directly on temp regulating center in the hypothalamus.
Antipyretic
Anti-inflammatory, antiplatelet, antipyretic, non-opioid analgesic. Blocks the enzyme needed for prostaglandin synthesis, which cause local vasodilation with swelling and pain.
Aspirin
Laxative, stool softener. To treat constipation. Acts as a surfactant that softens stool by decreasing surface tension between oil and water in feces.
Docusate Sodium
Laxative. To treat constipation. Herbal supplement
Senna
To treat deficiency, rickets, osteomalacia, hypophosphatemia, hypoparathyroidism, intestinal malabsorption.
Vitamin D (Ergocalciferol)
To treat deficiency caused by nutritional intake imbalance or pernicious anemia
Vitamin B-12 (hydroxycobalamin)
Antidepressant, antiobsessant, antipanic. To treat major depression, OCD, panic disorder and premenstrual dysphoric disorder. Inhibits reuptake of the neurotransmitter serotonin by CNS neurons, increasing the amount of serotonin available in nerve synapses.
Sertraline (Zoloft)
Antianginal, antihypertensive, MI prophylaxis and treatment. Inhibits stimulation of beta1 receptor sites, resulting in decreased cardiac excitability, cardiac output, and myocardial oxygen demand, which helps to relieve angina and reduce blood pressure. Given for this patient’s history of MI.
Metoprolol
Antihypertensive, vasodilator. Inhibits conversion of angiotensin I to angiotensin II; decreases release of aldosterone which reduces sodium and water reabsorption and increases their secretion, thus reducing blood pressure. To treat the patient’s hypertension.
Lisinopril
Class III antiarrhythmic. Relaxes vascular smooth muscles and improved myocardial blood flow, relaxes peripheral vascular smooth muscles decreasing peripheral vascular resistance and myocardial oxygen consumption.
Amiodarone
Antihypertensive, diuretic. Inhibits sodium and water reabsorption in the loop of Henle and increases urine formation. Also reduces intracellular and extracellular fluid volume, thus reducing blood pressure and cardiac output.
Furosemide (Lasix)
Used to treat symptoms of hay fever and other allergies.
Loratadine
Expectorant. To relieve cough, especially when secretions are thick, and to promote a productive cough. Increases fluid and mucus removal from the upper respiratory tract by increasing the volume of secretions and reducing their adhesiveness and surface tension.
Guaifenesin
Bronchodilator. To prevent exercise-induced asthma, to treat bronchospasm in pts with reversible obstructive airway disease or acute bronchospastic attack. Relaxes bronchial smooth-muscle cells and inhibits histamine release.
Albuterol
Interacts with verapamil, digoxin, methotrexate, St. John’s wort, and warfarin. Adverse reactions include agitation, dizziness, chest pain, hypertension, hypoglycemia, abd pain, and cough. Give before meals, preferably in the morning. Increases the risk for osteoporosis, monitor for hypomagnesemia, avoid alcohol, aspirin, ibuprofen and foods that increase gastric secretions.
Omeprazole
Interacts with digoxin, diuretics, methotrexate and warfarin. Adverse reactions include anxiety, confusion, chest pain, hyperglycemia, abd pain, bronchitis. Administer delayed-release 30 minute before a meal mixed in apple juice or applesauce, if given through an NG tube mix in apple juice ONLY. Monitor PT, INR and indication of C. diff infection. Monitor for hypomagnesemia, can expect relief within 2 weeks of starting therapy.
Pantoprazole
Interacts with antacids, bone marrow depressants. Adverse reactions include anxiety, confusion, arrhythmias, palpitations, dry mouth, abd pain, decreased libido, bronchospasm, acne. Shake oral suspension vigorously for 5 – 10 seconds before administration, Wait 30 – 60 minutes after taking famotidine before taking an antacid, avoid alcohol and smoking.
Famotidine
Interacts with ACE inhibitors, thiazide diuretics, vitamin C. Adverse reactions include chills, drowsiness, vasculitis, abd pain, exacerbated renal calculi, and alopecia. Obtain baseline CBC and uric acid level and renal and liver function tests before and during therapy, don’t give vitamin C, drink at least 10 large glasses of water daily, results for prevention of acute gout attacks may take up to 2 weeks or longer.
Allopurinol
Interacts with anticholinergics, antihypertensives, CNS depressants, MAO inhibitors, other opioids. Adverse reactions include coma, depression, bradycardia, altered taste, abd pain, muscle rigidity, apnea, decreased libido. Should not be given to children following tonsillectomy and/or adenoidectomy, Monitor respirations, assess for urinary retention, can take with food.
Codeine
Contraindicated with bronchial asthma or hypercarbia, significant respiratory depression. Interacts with anticholinergics, CNS depressants, mixed agonist/antagonist analgesics. Adverse reactions include anxiety, hypercholesterolemia, dry mouth, hot flashes, abd pain, respiratory depression, UTI, dehydration. Use caution in pts with COPD, the elderly, debilitated patients, do not administer to a pt wearing a transdermal fentanyl patch until it has been removed for 18 hours. Monitor for respiratory depression, constipation, expect to taper dosage every 2 – 4 days, monitor vitals closely, encourage plenty of high-fiber foods.
Hydrocodone
Contraindicated with severe hepatic impairment, severe active liver disease. Interacts with anticholinergics, barbiturates, oral contraceptives, warfarin, alcohol. Adverse reactions include abdominal pain, hepatotoxicity, hemolytic anemia, anaphylaxis. Tablets may be crushed or swallowed whole, serious skin reactions may occur, though rare.
Acetaminophen
Contraindicated in patients with peptic ulcer disease. Interacts with ACE inhibitors, NSAIDs and anticoagulants. Adverse reactions include confusion tinnitus, GI bleeding. Administer with food or after meals to minimize GI upset. Monitor for bleeding.
Aspirin
Contraindicated for fecal impaction, intestinal obstruction, nausea, vomiting or other symptoms of appendicitis, undiagnosed abdominal pain. Interacts with mineral oil and tetracycline. Adverse reactions include dizziness, syncope, palpitations, abdominal cramps and distention, and muscle weakness. Patients should expect long-term use. Administer with a full glass of water or milk.
Docusate Sodium
Contraindicated with Crohn’s disease, ulcerative colitis, heart disease, stomach pain, nausea, vomiting. Do not take if pregnant or breast feeding, effects are unknown.
Senna
Rotate sites for IM and SQ injections, avoid rapid administration to prevent fainting or dizziness when administering IV, incompatible with many drugs, protect from air and light.
VItamin C
Will decompose in light
VItamin D
Incompatible with many drugs, subQ should be injected deeply, protect from light.
Vitamin B12
Interacts with antipsychotics, aspirin, NSAIDs, warfarin, MAO inhibitors, tricyclic antidepressants. Adverse reactions include abnormal dreams, agitation, atrial arrhythmias, hyperglycemia, abdominal cramps or pain, acute renal failure, bronchospasm, coughing, diaphoresis. Monitor for serotonin syndrome (agitation, hallucinations, coma, tachycardia, labile blood pressure, hyperthermia, nausea, vomiting, diarrhea, incoordination). Monitor for mania and suicidal tendencies. Dilute oral concentrate before taking, and take immediately after mixing.
Sertraline
Contraindicated in acute heart failure, pulse less than 45 bpm, cardiogenic shock. Interacts with calcium channel blockers, antiarrhythmics, antidepressants, estrogens, insulin, and all foods. Adverse reactions include anxiety, angina, arrhythmias, blurred vision, constipation. Use caution in patients with CHF, monitor glucose and heart rhythm/rate, notify prescriber if pulse rate falls below 60 bpm.
Metoprolol
Contraindicated in patients with diabetes or renal impairment. Interacts with diuretics, insulin, NSAIDs, high potassium diet. Adverse reactions include ataxia, confusion, arrhythmias, chest pain, altered glucose levels, abdominal pain, renal failure, bronchospasm. Use caution in patients with fluid volume deficit, heart failure, impaired renal function, or sodium depletion. Monitor for persistent nonproductive cough.
Lisinopril
Incompatible with heparin. Contraindicated in bradycardia that causes syncope (unless pacemaker is present), cardiogenic shock, hypokalemia, hypomagnesemia, SA node dysfunction, second- and third- degree AV block (unless pacemaker is present). Interacts with anticoagulants, beta blockers, calcium channel blockers, St. john’s wort, digoxin, fentanyl, lidocaine, warfarin, grapefruit juice. Adverse reactions include ataxia, confusion, arrhythmias, abd pain, acute renal failure, muscle weakness, acute respiratory distress syndrome. If pt has an implantable cardiac device, monitor because drug can affect pacing or defibrillating thresholds, may cause phlebitis are higher rates, monitor continuous EKG, may cause or worsen pulmonary disorders that develop after therapy.
Amiodarone
Incompatible with highly acidic solutions. Interacts with ACE inhibitors, digoxin, insulin, NSAIDs, norepinephrine, thiazide diuretics. Adverse reactions include dizziness, drowsiness, arrhythmias, blurred vision, hyperglycemia, abd cramps, muscle pain or spasms. Use caution in pts with advanced hepatic cirrhosis, allergy to sulfonamides, give in the a.m., monitor weight, blood pressure, and lab values, take at same time each day, pt should eat more high-potassium foods.
Furosemide
Can be taken with or without food. Do not use to treat hives that are bruised or blistered, that are an unusual color, or that do not itch.
Loratadine
Adverse reactions include dizziness, headache, nausea and vomiting, rash. Take each dose with a full glass of water, increase fluid intake to help thin secretions unless contraindicated, do not take longer than 1 week and notify prescriber about fever, persistent headache, or rash.
Guaifenesin
Interacts with beta blockers, bronchodilators, digoxin, MAO inhibitors, potassium-wasting diuretics. Adverse reactions include anxiety, drowsiness, angina, arrhythmias, altered taste, hyperglycemia, UTI, muscle cramps. Administer inhalations during second half of administration. Use caution in pts with cardiac disorders, diabetes, digitalis intoxication, hypertension, hyperthyroidism, or history of seizures. Shake inhaler before use and spray 1 – 4 times into the air before use, wash mouthpiece once a week and let air dry, wait at least 1 minute between
Albuterol
- an additional substance, treatment, or procedure used for increasing the efficacy or safety of the primary substance, treatment, or procedure or for facilitating its performance
Adjunct Analgesic
- an effect wherein two or more substances or actions used in combination produce a total effect, the same as the arithmetic sum of the individual effects.
Additive Effect
the interaction of elements that when combined produce a total effect that is greater than the sum of the individual elements, contributions
synergistic effect
when their interaction causes a decrease in the effects of one or both of the drugs. Both synergy and antagonism can both occur during different
Antagonistic effect
Erikson’s stage for middle adulthood (35-65)
Generativity vs. Stagnation