Final Flashcards
Cell cycles stages
M phase (PMAT) - mitosis (nuclear division) - cytokinesis (cytoplasmic division) Interphase between m phases - G1 phase (cell growth) - S phase (DNA replication) - G2 phase (more growth) Back to mitosis
Mitosis
Nuclear division (exact copy)
Meiosis
Cytokinesis and cell splitting (sex cells)
Interphase needs how much time?
long enough for the cell to double in size, so replications don’t reduce overall amount.
Cell cycle is dependent activated on…
cyclically activated protein kinases (Cdks)
How do cyclins function?
No enzymatic activity of their own, but they bind cdks to activate them
Kinesin
motor protein moving vesicles to + end of microtubules
Dynein
Opposite of Kinesin
How do vesicles reverse direction?
Multiple motor proteins can be attached at once (Kinesin + Dynein). Reversals can happen when some detach or others take over
ion channel coupled receptors
cell surface receptor
-
G-protein coupled receptor
Cell surface receptor
- responds to extra-cellular signal pathways
Enzyme coupled receptors
cell surface receptor
- responds to extra-cellular signal pathways
G-protein
- regulate ion channels and plasma enzymes
- binds gtp and hydrolyzes to act as signal switch. signal then shut down
Cell cycle control system
state based checks to ensure the conditions are favorable to continue
What is a kinase?
enzyme to catalyze tranfer of phosphate groups
RTK
- signaling molecule attaches to signaling binding site
- this causes dimer formation from monomers
- activated tyrosine regions allow phosphorylation of dimer
- phosphate will be taken from ATP
- relay proteins attach to phosphorylated Tyr to begin signal transduction pathway
Basic signal transduction pathway
Receptor (G protein)
transduction
secondary messenger (cAMP)
target cells
Haploid v Diplod
haploid = sperm, n = 23 diploid = zygote, n = 46
Prophase
(Prepare)
nucleolus dissolves
condense and separate
form the spindle
Metaphase
(Meet)
alignment in plate
Anaphase
(Apart)
chromatids separate towards poles
Telophase
(The end)
New nuclear envelope forms
chromosomes unfold back to chromatin
Chromosome
two sister chromatids in symmetric x shape
centromere in middle