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Immuno final > final > Flashcards

final Flashcards

1
Q

The goal of vaccination is best described by?

A

attempt to stimulate adaptive immune system to create memory

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2
Q

antacids have a large source of?

A

aluminum

antiperspirants are 2nd

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3
Q

to create memory killer t cells what must occur?

A

infected cell must present antigen on MHCI

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4
Q

vaccine where organism is created and genes are removed that impair virulence and/or replicate describes?

A

recombinate vaccine

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5
Q

Thimersol/mercury is in what vaccines?

A

influenza and DTAP

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6
Q

what’s the function of an immunologic adjuvant?

A

increases immune response

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7
Q

in the brain aluminum does what?

A

increases level of pro inflammatory cytokines

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8
Q

what percentage of the world is infected by tb?

A

1/3

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9
Q

what percentage actually develop tb?

A

5-10%

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10
Q

how does tb create a problem for macrophages?

A

prevents phagosome from fusing with lysosome

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11
Q

what bias is associated with allergy and asthma?

A

Th2

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12
Q

self reactive antibodies against ACH receptors prevents ACH from binding producing muscle weakness is?

A

myasthenia gravis

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13
Q

autoimmune dieases typically follow what?

A

infection

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14
Q

healthy 6 month old has was Th bias?

A

Th1

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15
Q

antibody associated with allergies?

A

IgE

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16
Q

Tb macrophages die how?

A

necrosis

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17
Q

in utero you have what Th bias?

A

Th2

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18
Q

hypersensitivity associated with allergies?

A

type 1 (immediate)

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19
Q

all forms of hypersensitivity require?

A

prior exposure to antigen

20
Q

type of hypersensitivity associated with poison ivy?

A

type 4

21
Q

deposition of antibody-antigen complexes causing INFLAMMATION is what type?

A

type 3

22
Q

why can the HIV-1 virus evade the immune system thus no vaccine?

A

high mutation rate

23
Q

most cancers are linked to viral infections?

A

false

24
Q

which immune cells are likely effective for cancer?

A

NK cells
(2nd macrophages)
(CTL’s are least effective)

25
Q

What is found on the surface of cancer cells that impairs the immune systems ability to destroy the aberrant cell?

A

PD-L1

26
Q

Pus is formed from?

A

neutrophils

27
Q

what helps surveillance against cancer?

A

innate

NK and macro

28
Q

what knocks out immune function by attacking helper T cells?

A

AIDS

CD4–>helper T cells

29
Q

Normal function of IgE is to act as a guidance system for which of the following cells, targeting its chemistry at larger parasites so they can be destroyed with minimal damage?

A 
mast cells
(then comes basophils from blood and then eosinophils from the bone marrow) eosinophils are "delayed" reaction to allergy
30
Q

what percentage of the US pop is affected by AI disease?

A

5-7.5%

31
Q

immune system attack on myelin basic protein in CNS is?

A

multiple sclerosis

32
Q

in order for an AI disease to develop there must be?

A

inflammation in the body

33
Q

In order to create memory helper T cells what must occur?

A

antigen presenting cell must present the antigen on MHC2

34
Q

what is an attenuate vaccine?

A

live organisms whose virulence is weakened

35
Q

DNA has been extracted from pathogen and used to make vaccine?

A

DNA vaccine

36
Q

what causes sepsis?

A

overreaction to widespread inflammatory response

37
Q

breakdown in B and T cell tolerance?

A

lupus

38
Q

breakdown of myelin in PNS?

A

Guillian-barre

39
Q

what hypersensitivity is associated with T cells?

A

type 4

40
Q

AB mediated IgM and/or IgG is what type?

A

type 2

41
Q

what percent of human cancers are linked to viral infections?

A

15-20%

42
Q

Memory B and T cells can be produced efficiently even when no immune system cells have been infected by the attacker?

A

TRUE

43
Q

anti-inflammatory cholinergic response is from?

A

the vagus nerve

44
Q

in order to create memory B cells what must occur?

A

antigen coming to a secondary lymph organ via lymph or blood

45
Q

aluminum induces a?

A

Th2 biased syndrome

46
Q

Allergies are caused by?

A

overproduction of IgE AB

47
Q

name the types of hypersensitivity..

A

type 1- allergies
type 2- AB mediated IgM/IgG
type 3- immune complex (INFLAMMATION) IgM/IgG
type 4- cell mediated T-cells (poison ivy)

Immuno final (1 decks)

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