Final Flashcards
What is Evidence-Based Practice (EBP)?
EBP is a systematic approach to clinical decision-making that integrates the best available research evidence, clinical expertise, and patient values and preferences.
What are the 3 pillars of EBP?
- Best research evidence, 2. Clinical expertise, 3. Patient values and preferences.
What are the benefits of EBP?
Improves patient satisfaction, reduces harm, promotes individualized care, enhances treatment and diagnosis, improves outcomes, and may lower healthcare costs.
When is EBP best applied?
When research evidence is combined with patient experiences and clinician expertise.
What is the PICO(T) format?
A framework to structure clinical questions: P=Patient/Population, I=Intervention, C=Comparison, O=Outcome, T=Timeframe (optional).
Why is Step 1 of EBP (clinical question) important?
It directs the search, narrows down evidence, saves time, and improves clinical outcomes.
What are the types of clinical questions in EBP?
Therapy, Diagnosis, Prognosis, Etiology, Prevention.
What is qualitative research?
Non-numerical research focused on understanding the ‘why’ and ‘how’ of human behavior, often through words, feelings, and experiences.
What are examples of qualitative methods?
Ethnography, narrative, phenomenological, grounded theory, and case study.
What is quantitative research?
Research involving numerical data to quantify variables and test hypotheses using statistical methods.
What are the four types of quantitative research?
Descriptive, Correlational, Causal-comparative/quasi-experimental, Experimental.
What is the evidence hierarchy?
A pyramid ranking research by quality: Systematic reviews/meta-analyses > RCTs > Cohort studies > Case-control studies > Case reports > Expert opinion.
What is the 6S pyramid?
A hierarchy of evidence: Systems, Summaries, Synopses of Syntheses, Syntheses, Synopses of Single Studies, Single Studies.
What is sensitivity?
The ability of a test to correctly identify those with the condition (true positive rate).
What is specificity?
The ability of a test to correctly identify those without the condition (true negative rate).
What is PPV (Positive Predictive Value)?
The proportion of positive test results that are true positives.
What is NPV (Negative Predictive Value)?
The proportion of negative test results that are true negatives.
What is a likelihood ratio?
A statistic that indicates how much a test result will change the odds of having a disease.
What is critical appraisal?
The process of systematically evaluating research for its trustworthiness, relevance, and value in a specific context.
What are common appraisal pitfalls?
Low-quality research, bias, misleading results, and false conclusions.
What is the purpose of Institutional Review Boards (IRBs)?
To ensure ethical standards are met in research involving human participants.
What are the three IRB review types?
Exempt (minimal risk), Expedited (low risk), Full Board (more than minimal risk).
What are the ethical principles in research?
Autonomy, Beneficence, Justice, and avoidance of Deception.
What must informed consent include?
Disclosure, understanding, voluntariness, competence, and clear consent without exculpatory language.