final Flashcards
Define Naturally acquired immunity
is gained through normal events such as illness
Define Artificially acquired immunity
is gained through immunization
Active immunity
results from exposure to antigen
passive immunity
results from addiction of others antibodies
where is natural immunity found
during pregnancy, mother IgG antibodies cross the placenta, breast milk contains secretory IgA
injection of —– containing antibodies
antiserum
what is antitoxin
is antiserum that protects against a toxin
Hyperimmune globulin
antibodies to specific disease
define immune globulin
IgG Fraction from many donors; variety of antibodies
define vaccine
IS prepared of pathogens or its products used to induce active immunity
what is herd immunity
develops when a critical portion of the population is immune to disease infectious agents unable to spread due to insufficient susceptible host
Attenuated vaccine
weakened form of pathogens, stronger immune response but may cause disease
inactivated vaccine
weaker immune response but cannot cause infections
advantages of attenuated vaccine
single dose usually induces long-lasting immunity due to microbe multiplying in body
can inadvertently immunize other by spreading
the disadvantage of the attenuated vaccine
can sometimes cause disease in immunosuppressed individuals
can occasionally every or mutant become pathogenic
generally not recommended for pregnant women
usually need to refrigeration
advantage of an inactive vaccine
cannot use infections or revert to pathogenic forms
the disadvantage of inactivated vaccine
no replication, so no amplification, several booster doses are usually needed
What is adjuvant
a substance that enhances immune response to antigens
what are toxoid vaccines
toxins treated to destroy toxic part, retain antigenic epitopes
what are subunit vaccines
consists of key proteins antigens or antigenic fragments from pathogens
what does an inactivated whole-agent vaccine contain
contains killed microorganisms or inactivated viruses
what is VLP vaccines
(Virus-like particles) empty capsids produced by genetically engineered organisms
what is not effective in young children
independent antigens
conjugated vaccines-
polysaccharides linked to protines